anti-F2R (F2R) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 186 Coagulation Factor II (thrombin) Receptor (F2R) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen F2R Kits (65) und F2R Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 272 F2R Produkte verfügbar.
Synonyme:
AI482343, BXR, Cf2r, f2r-a, HTR, ONR1, PAR, Par-1, Par1, PAR2, PARq, PRR, PXR, SAR, SXR, ThrR, TR, TRGPC
Alle Antikörper anzeigen Gen GeneID UniProt
F2R 2149 P25116
F2R 14062 P30558
F2R 25439  

Meistgesuchte Reaktivitäten zu anti-F2R (F2R) Antikörper

anti-Human F2R Antikörper:

anti-Mouse (Murine) F2R Antikörper:

anti-Rat (Rattus) F2R Antikörper:

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Weitere Antikörper gegen F2R Interaktionspartner

Human Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. In intrahepatic cholestasis of pregnancy, gene silencing of miR (zeige MLXIP Antikörper)-148a upregulated PXR (zeige NR1I2 Antikörper) expression which was inhibited by estradiol in liver cells. miR (zeige MLXIP Antikörper)-148a may be involved in the estrogen induction in ICP via PXR (zeige NR1I2 Antikörper) signaling. MRP3 (zeige ABCC3 Antikörper) may be involved.

  2. Data suggest that the abrogation of protease-activated receptor 1 (PAR1)-dependent signaling pathways may prove a promising strategy for gliomas.

  3. these data indicate that KLKB1 (zeige KLKB1 Antikörper) induces inflammatory reactions in human dental tissues via protease-activated receptor 1

  4. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (zeige F2 Antikörper)-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper)-deleted MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells. Similar to the effect of Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper) deletion, PAR-1 (zeige MARK2 Antikörper) overexpression induced CDKN1A/p21 (zeige CDKN1A Antikörper) expression and attenuated proliferation in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells

  5. this study shows that PXR (zeige NR1I2 Antikörper) augments Mycobacterium tuberculosis survival inside the host macrophages by promoting the foamy macrophage formation and abrogating phagolysosomal fusion, inflammation, and apoptosis

  6. PXR (zeige NR1I2 Antikörper) is a potential biomarker for predicting outcome and activates MRP3 (zeige ABCC3 Antikörper) transcription by directly binding to its promoter resulting in an increased L-OHP efflux capacity, and resistance to L-OHP or platinum drugs in CRC (zeige CALR Antikörper).

  7. This is the first time an association between NR1I2 (zeige NR1I2 Antikörper) polymorphism and time of progression to AIDS is reported and supports an apparent relationship between the gene in the immune response and identifies another genetic factor influencing AIDS progression.

  8. Data highlight functional differences in proliferation and barrier integrity between dark keratinocytes and fair keratinocytes that are partly associated with their differential expression of PAR1 (zeige MARK2 Antikörper) and PAR2 (zeige F2RL1 Antikörper).

  9. MD simulations further revealed that the presence of small molecule at allosteric site disrupts the LBD dynamics and locks the LBD in a "tightly-contracted" conformation. The molecular details provided here could guide new structural studies to understand PXR (zeige NR1I2 Antikörper) activation and antagonism.

  10. Extracellular granzyme K (zeige GZMK Antikörper) mediates endothelial activation through the cleavage of PAR-1 (zeige MARK2 Antikörper).

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. In this study, we found upregulation of several hemostasis-related genes, including the thrombin (zeige F2 Antikörper)-activatable receptor PAR-1 (protease-activated receptor-1), in Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper)-deleted MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells. Similar to the effect of Runx1 (zeige RUNX1 Antikörper)/Cbfb (zeige CBFB Antikörper) deletion, PAR-1 (zeige MARK2 Antikörper) overexpression induced CDKN1A/p21 (zeige CDKN1A Antikörper) expression and attenuated proliferation in MLL (zeige MLL Antikörper)-AF9 (zeige MLLT3 Antikörper) cells

  2. our findings define a detrimental role of thrombin (zeige F2 Antikörper)-activated PAR-1 (zeige MARK2 Antikörper) in wound healing in mice with spinal cord injuries.

  3. thrombin (zeige F2 Antikörper)/PAR-1 (zeige MARK2 Antikörper) interaction regulated MCP-1 (zeige CPT1B Antikörper), TF, MCSF (zeige CSF1 Antikörper) and IL-6 (zeige IL6 Antikörper) production.

  4. Thrombin (zeige F2 Antikörper) upregulates LCN2 (zeige LCN2 Antikörper) through protease-activated receptor-1 activation and causes brain damage.

  5. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (zeige MMP1 Antikörper)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  6. Data indicate an involvement of protease-activated receptor-1 in the neuroinflammation mediated by Eomes (zeige EOMES Antikörper)(+) CD4 (zeige CD4 Antikörper)(+) T cells.

  7. Bladder PAR (zeige AFG3L2 Antikörper) activation elicits urothelial MIF (zeige MIF Antikörper) release and urothelial MIF (zeige MIF Antikörper) receptor signaling at least partly through CXCR4 (zeige CXCR4 Antikörper) to result in abdominal hypersensitivity without overt bladder inflammation

  8. Data suggest that the pro-fibrotic effects of protease-activated receptor PAR-1 (zeige MARK2 Antikörper) require the presence of protease-activated receptor PAR-2 (zeige F2RL1 Antikörper).

  9. Thrombin (zeige F2 Antikörper)-PAR1 signaling, via nitric oxide and EPCR (zeige PROCR Antikörper), promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) mobilization. aPC (zeige APC Antikörper)-EPCR (zeige PROCR Antikörper)-PAR1 signaling promotes HSC (zeige FUT1 Antikörper) retention in bone marrow.

  10. Colonic adenocarcinoma growth was reduced in PAR-1 (zeige MARK2 Antikörper)-deficient mice. Stromal cell-associated PAR-1 (zeige MARK2 Antikörper) as one thrombin (zeige F2 Antikörper) target important for tumor outgrowth.

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. MMP-1 (zeige MMP1 Antikörper) promotes VEGFR2 (zeige KDR Antikörper) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (zeige NFKB1 Antikörper)

  2. PAR1 and PAR2 (zeige F2RL1 Antikörper) regulate endothelial NO synthase (zeige NOS Antikörper) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. Thrombin (zeige F2 Antikörper) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (zeige RHOA Antikörper), and myocardin (zeige MYOCD Antikörper).

  2. Thrombin (zeige F2 Antikörper) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (zeige CA2 Antikörper)+).

F2R Antigen-Profil

Beschreibung des Gens

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with F2R

  • coagulation factor 2 (thrombin) receptor (f2r) Antikörper
  • coagulation factor II (thrombin) receptor (F2R) Antikörper
  • coagulation factor II (thrombin) receptor (F2r) Antikörper
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2) Antikörper
  • AI482343 Antikörper
  • BXR Antikörper
  • Cf2r Antikörper
  • f2r-a Antikörper
  • HTR Antikörper
  • ONR1 Antikörper
  • PAR Antikörper
  • Par-1 Antikörper
  • Par1 Antikörper
  • PAR2 Antikörper
  • PARq Antikörper
  • PRR Antikörper
  • PXR Antikörper
  • SAR Antikörper
  • SXR Antikörper
  • ThrR Antikörper
  • TR Antikörper
  • TRGPC Antikörper

Bezeichner auf Proteinebene für F2R

PAR-1 , coagulation factor II (thrombin) receptor , coagulation factor II receptor , proteinase-activated receptor 1 , thrombin receptor , protease-activated receptor 1 , Thrombin receptor , protease-activated receptor-1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor

GENE ID SPEZIES
378526 Xenopus laevis
2149 Homo sapiens
14062 Mus musculus
25439 Rattus norvegicus
526585 Bos taurus
100521609 Sus scrofa
8856 Homo sapiens
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