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anti-F2R (F2R) Antikörper

anti-Coagulation Factor II (thrombin) Receptor Antikörper (F2R)
Auf finden Sie aktuell 181 Coagulation Factor II (thrombin) Receptor (F2R) Antikörper von 26 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen F2R Kits (62) und F2R Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 264 F2R Produkte verfügbar.
AI482343, BXR, Cf2r, f2r-a, HTR, ONR1, PAR, Par-1, Par1, PAR2, PARq, PRR, PXR, SAR, SXR, ThrR, TR, TRGPC

Meistgesuchte Reaktivitäten zu anti-F2R (F2R) Antikörper

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anti-Human F2R Antikörper:

anti-Mouse (Murine) F2R Antikörper:

anti-Rat (Rattus) F2R Antikörper:

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Am meisten referenzierte anti-F2R Antikörper

  1. Human Monoclonal F2R Primary Antibody für IF, WB - ABIN968573 : Coughlin: How the protease thrombin talks to cells. in Proceedings of the National Academy of Sciences of the United States of America 1999 (PubMed)
    Zeige alle 4 Referenzen für ABIN968573

  2. Human Polyclonal F2R Primary Antibody für WB - ABIN611146 : Gradin, Larsson, Marklund, Gullberg: Regulation of microtubule dynamics by extracellular signals: cAMP-dependent protein kinase switches off the activity of oncoprotein 18 in intact cells. in The Journal of cell biology 1998 (PubMed)
    Zeige alle 3 Referenzen für ABIN611146

  3. Human Monoclonal F2R Primary Antibody für ELISA, ICC - ABIN4343604 : Gonda, Watanabe, Ohuchi, Higuchi: In vivo nano-imaging of membrane dynamics in metastatic tumor cells using quantum dots. in The Journal of biological chemistry 2010 (PubMed)
    Zeige alle 2 Referenzen für ABIN4343604

  4. Human Polyclonal F2R Primary Antibody für ELISA, WB - ABIN1536155 : Vu, Hung, Wheaton, Coughlin: Molecular cloning of a functional thrombin receptor reveals a novel proteolytic mechanism of receptor activation. in Cell 1991 (PubMed)

  5. Human Polyclonal F2R Primary Antibody für ICC, IF - ABIN1742020 : Ossovskaya, Bunnett: Protease-activated receptors: contribution to physiology and disease. in Physiological reviews 2004 (PubMed)

  6. Human Monoclonal F2R Primary Antibody für FACS - ABIN4897018 : Hagag, Nosair, Ghaith, Elshenawy: Prognostic value of protease activated receptor-1 in children with acute lymphoblastic leukemia. in Mediterranean journal of hematology and infectious diseases 2014 (PubMed)

  7. Human Polyclonal F2R Primary Antibody für WB - ABIN452298 : Niessen, Schaffner, Furlan-Freguia, Pawlinski, Bhattacharjee, Chun, Derian, Andrade-Gordon, Rosen, Ruf: Dendritic cell PAR1-S1P3 signalling couples coagulation and inflammation. in Nature 2008 (PubMed)

  8. Guinea Pig Polyclonal F2R Primary Antibody für WB - ABIN2784606 : Kamio, Hashizume, Nakao, Matsushima, Sugiya: Plasmin is involved in inflammation via protease-activated receptor-1 activation in human dental pulp. in Biochemical pharmacology 2008 (PubMed)

Weitere Antikörper gegen F2R Interaktionspartner

Human Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. Extracellular granzyme K (zeige GZMK Antikörper) mediates endothelial activation through the cleavage of PAR-1 (zeige MARK2 Antikörper).

  2. Pregnane X receptor interacts with liver X receptor to regulate expression of SMPDL3A in primary hepatocytes.

  3. 66034T/C polymorphism of the human pregnane X receptor (zeige NR1I2 Antikörper) (hPXR) is potential risk factor for drug-resistant epilepsy.

  4. The data suggest that some of the natural PXR (zeige NR1I2 Antikörper) variants may have adverse physiological consequences owing to its influence on the expression levels and functional output of drug-metabolizing enzymes and transporters.

  5. miR (zeige MLXIP Antikörper)-30c-1-3p was shown to alter the expression of CYP3A4 (zeige CYP3A4 Antikörper), a prototypical target gene of PXR (zeige NR1I2 Antikörper).

  6. The nuclear receptor PXR (zeige NR1I2 Antikörper) regulates hepatic energy metabolism. (Review)

  7. Novel functions of PXR (zeige NR1I2 Antikörper) in cardiometabolic disease development have been described. (Review)

  8. Acetylation of lysine 109 modulates PXR (zeige NR1I2 Antikörper) DNA binding and transcriptional activity; PXR (zeige NR1I2 Antikörper) acetylation status and transcriptional activity are modulated by E1A binding protein (p300 (zeige EP300 Antikörper)) and SIRT1 (zeige SIRT1 Antikörper).

  9. Genome-wide comparison of the inducible transcriptomes of nuclear receptors CAR, PXR (zeige NR1I2 Antikörper) and PPARalpha (zeige PPARA Antikörper) in primary human hepatocytes has been presented.

  10. PXR (zeige NR1I2 Antikörper) regulates the intestinal epithelial barrier during inflammation by modulating cytokine-induced MLCK (zeige MYLK Antikörper) expression and JNK1 (zeige MAPK8 Antikörper)/2 activation

Mouse (Murine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. thrombin (zeige F2 Antikörper)/PAR-1 (zeige MARK2 Antikörper) interaction regulated MCP-1 (zeige CPT1B Antikörper), TF, MCSF (zeige CSF1 Antikörper) and IL-6 (zeige IL6 Antikörper) production.

  2. Thrombin (zeige F2 Antikörper) upregulates LCN2 (zeige LCN2 Antikörper) through protease-activated receptor-1 activation and causes brain damage.

  3. Matrix metalloproteinases (MMP) are effectors of hippocampal neuroplasticity in the adult central nervous system and that the MMP-1 (zeige MMP1 Antikörper)/protease-activated receptor-1 axis may play a role in neurogenesis following physiological and/or pathological stimuli.

  4. Data indicate an involvement of protease-activated receptor-1 in the neuroinflammation mediated by Eomes (zeige EOMES Antikörper)(+) CD4 (zeige CD4 Antikörper)(+) T cells.

  5. Bladder PAR (zeige AFG3L2 Antikörper) activation elicits urothelial MIF (zeige MIF Antikörper) release and urothelial MIF (zeige MIF Antikörper) receptor signaling at least partly through CXCR4 (zeige CXCR4 Antikörper) to result in abdominal hypersensitivity without overt bladder inflammation

  6. Data suggest that the pro-fibrotic effects of protease-activated receptor PAR-1 (zeige MARK2 Antikörper) require the presence of protease-activated receptor PAR-2 (zeige F2RL1 Antikörper).

  7. Thrombin (zeige F2 Antikörper)-PAR1 signaling, via nitric oxide and EPCR (zeige PROCR Antikörper), promotes hematopoietic stem cell (HSC (zeige FUT1 Antikörper)) mobilization. aPC (zeige APC Antikörper)-EPCR (zeige PROCR Antikörper)-PAR1 signaling promotes HSC (zeige FUT1 Antikörper) retention in bone marrow.

  8. Colonic adenocarcinoma growth was reduced in PAR-1 (zeige MARK2 Antikörper)-deficient mice. Stromal cell-associated PAR-1 (zeige MARK2 Antikörper) as one thrombin (zeige F2 Antikörper) target important for tumor outgrowth.

  9. Interference with the thrombin (zeige F2 Antikörper)-PAR1 system does not reduce the adverse effects of blood on germinal cells of the immature mouse brain.

  10. Protease activated receptor-1 deficiency diminishes bleomycin-induced skin fibrosis

Cow (Bovine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. MMP-1 (zeige MMP1 Antikörper) promotes VEGFR2 (zeige KDR Antikörper) expression and proliferation of endothelial cells through stimulation of PAR-1 and activation of NF-kappaB (zeige NFKB1 Antikörper)

  2. PAR1 and PAR2 (zeige F2RL1 Antikörper) regulate endothelial NO synthase (zeige NOS Antikörper) phosphorylation and activity through G(12/13) and G(q), delineating the signaling pathways by which the proteases act on protease-activated receptors to modulate endothelial functions.

Pig (Porcine) Coagulation Factor II (thrombin) Receptor (F2R) Interaktionspartner

  1. Thrombin (zeige F2 Antikörper) stimulates swine smooth muscle cell differentiation from peripheral blood mononuclear cells via protease-activated receptor-1, RhoA (zeige RHOA Antikörper), and myocardin (zeige MYOCD Antikörper).

  2. Thrombin (zeige F2 Antikörper) induces a sustained contraction in the normal pulmonary artery, by activating PAR(1) and thereby increasing the sensitivity of the myofilament to Ca(2 (zeige CA2 Antikörper)+).

F2R Antigen-Profil

Beschreibung des Gens

This gene product belongs to the nuclear receptor superfamily, members of which are transcription factors characterized by a ligand-binding domain and a DNA-binding domain. The encoded protein is a transcriptional regulator of the cytochrome P450 gene CYP3A4, binding to the response element of the CYP3A4 promoter as a heterodimer with the 9-cis retinoic acid receptor RXR. It is activated by a range of compounds that induce CYP3A4, including dexamethasone and rifampicin. Several alternatively spliced transcripts encoding different isoforms, some of which use non-AUG (CUG) translation initiation codon, have been described for this gene. Additional transcript variants exist, however, they have not been fully characterized.

Alternative names and synonyms associated with F2R

  • coagulation factor 2 (thrombin) receptor (f2r) Antikörper
  • coagulation factor II (thrombin) receptor (F2R) Antikörper
  • coagulation factor II (thrombin) receptor (F2r) Antikörper
  • nuclear receptor subfamily 1, group I, member 2 (NR1I2) Antikörper
  • AI482343 Antikörper
  • BXR Antikörper
  • Cf2r Antikörper
  • f2r-a Antikörper
  • HTR Antikörper
  • ONR1 Antikörper
  • PAR Antikörper
  • Par-1 Antikörper
  • Par1 Antikörper
  • PAR2 Antikörper
  • PARq Antikörper
  • PRR Antikörper
  • PXR Antikörper
  • SAR Antikörper
  • SXR Antikörper
  • ThrR Antikörper
  • TR Antikörper
  • TRGPC Antikörper

Bezeichner auf Proteinebene für F2R

PAR-1 , coagulation factor II (thrombin) receptor , coagulation factor II receptor , proteinase-activated receptor 1 , thrombin receptor , protease-activated receptor 1 , Thrombin receptor , protease-activated receptor-1 , nuclear receptor subfamily 1 group I member 2 , orphan nuclear receptor PAR1 , orphan nuclear receptor PXR , pregnane X nuclear receptor variant 2 , pregnane X receptor , steroid and xenobiotic receptor

378526 Xenopus laevis
2149 Homo sapiens
14062 Mus musculus
25439 Rattus norvegicus
526585 Bos taurus
100521609 Sus scrofa
8856 Homo sapiens
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