TNFRSF13C Proteine (TNFRSF13C)

Auf finden Sie aktuell 36 Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Proteine von 12 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen TNFRSF13C Antikörper (218) und TNFRSF13C Kits (44) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 315 TNFRSF13C Produkte verfügbar.
2010006P15Rik, BAFF-R, Baffr, Bcmd, Bcmd-1, Bcmd1, BROMIX, CD268, CVID4, Lvis22, prolixin, RGD1560810, TNFRSF13C
alle Proteine anzeigen Gen GeneID UniProt
TNFRSF13C 500910  
TNFRSF13C 115650 Q96RJ3
TNFRSF13C 72049 Q9D8D0

TNFRSF13C Proteine (TNFRSF13C) nach Spezies

Weitere Proteine zu TNFRSF13C Interaktionspartnern

Human Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Interaktionspartner

  1. The expression levels of serum BAFF (zeige TNFSF13B Proteine) and the three receptors (TACI (zeige TNFRSF13B Proteine), BCMA (zeige TNFRSF17 Proteine) and BAFF-R) in non-Hodgkin lymphoma patients were significantly higher than in healthy controls.

  2. Variants in BAFF-R gene is associated with chronic lymphocytic leukemia.

  3. BAFF-R, as the principal receptor of BAFF (zeige TNFSF13B Proteine), not only decreased the apoptosis of B cells and CD8 (zeige CD8A Proteine)+ T cells by upregulating the expression of Bcl-2 (zeige BCL2 Proteine) and BclxL (zeige BCL2L1 Proteine), but also promoted B-cell proliferation in immune thrombocytopenia.

  4. BAFF (zeige TNFSF13B Proteine) and BAFF-R are expressed in the thyrocytes derived from patients with either autoimmune thyroid disorders or multinodular goiter, as well in the infiltrating immune cells of Graves' disease and Hashimoto's thyroiditis

  5. There is an increased prevalence of the BAFF-R His159Tyr mutation in patients with Sjogren's syndrome (SS), particularly in those with SS complicated by MALT lymphoma whose disease onset occurred at a younger age.

  6. Expression of mutant caspase-9 (zeige CASP9 Proteine) correlated with a downregulation of BAFFR (B-cell-activating factor (zeige TNFSF13B Proteine) belonging to the TNF (zeige TNF Proteine) family (BAFF) receptor) in B cells and ICOS (inducible T-cell costimulator (zeige ICOS Proteine)) in T cells.

  7. Variants of TNFRSF13C were associated with common variable immunodeficiency.

  8. Negative expression of BAFF-R, but not of BAFF (zeige TNFSF13B Proteine), could be an independent risk factor for progression-free survival and Overall survival in patients with diffuse large B-cell lymphoma treated with standard R-CHOP (zeige DDIT3 Proteine).

  9. the common TLR4 (zeige TLR4 Proteine)-D299G, TLR4 (zeige TLR4 Proteine)-T399I and BAFFR-P21R polymorphisms provide the carriers with a protective advantage against ICU-acquired sepsis; this finding was more profound for medical patients compared to trauma or surgical ones

  10. Data show significant differences in expression of tumour necrosis factor (zeige TNF Proteine) family (BAFF (zeige TNFSF13B Proteine)) receptors BAFF-R, BCMA (zeige TNFRSF17 Proteine) and TACI (zeige TNFRSF13B Proteine) in patients with and without anti-Jo-1 or anti-Ro52 (zeige TRIM21 Proteine)/anti-Ro60 (zeige TROVE2 Proteine) autoantibodies.

Mouse (Murine) Tumor Necrosis Factor Receptor Superfamily, Member 13C (TNFRSF13C) Interaktionspartner

  1. B cell-activating factor (BAFF (zeige TNFSF13B Proteine)) upregulates CD28 (zeige CD28 Proteine)/B7 and CD40 (zeige CD40 Proteine)/CD154 (zeige CD40LG Proteine) expression, and promotes the interactions between T and B cells in a BAFF receptor-dependent manner.

  2. conclude that P44S BAFFR mutation does not hinder BAFFR function or enhance B cell activity in MRL/Lpr (zeige FAS Proteine) and MRL mice and that other susceptibility loci on the MRL background contributed to the hyperactivity of these cells

  3. Results from this study suggest blockade of CXCL13 (zeige CXCL13 Proteine) and BAFFR together may be an effective therapeutic strategy in preventing salivary hypofunction and reducing autoantibody titers and sialadenitis in patients with Sjogren's syndrome

  4. Heteromers consisting of one BAFF (zeige TNFSF13B Proteine) and two APRIL bind to receptor TACI (zeige TNFRSF13B Proteine), BCMA (zeige TNFRSF17 Proteine) but not to BAFFR.

  5. Syk (zeige SYK Proteine)-deficient B cells require BAFF receptor and CD19 (zeige CD19 Proteine)/PI3K signaling for their long-term survival.

  6. In conclusion, BAFFR signaling affects both innate and adaptive immune activation during viral infections.

  7. BAFF (zeige TNFSF13B Proteine) controls neural cell survival through BAFF receptor.

  8. BAFF receptor deficiency limits Murid herpesvirus 4 infection.

  9. Although we have found that TACI is dispensable for controlling B. hermsii infection, mice deficient in BAFFR or BAFF exhibit impairment in B. hermsii-specific IgM responses and clearance of bacteremia.

  10. tnfrsf13c is dispensable for the development of SLE in NZM mice.

TNFRSF13C Protein Überblick

Protein Überblick

B cell-activating factor (BAFF) enhances B-cell survival in vitro and is a regulator of the peripheral B-cell population. Overexpression of Baff in mice results in mature B-cell hyperplasia and symptoms of systemic lupus erythematosus (SLE). Also, some SLE patients have increased levels of BAFF in serum. Therefore, it has been proposed that abnormally high levels of BAFF may contribute to the pathogenesis of autoimmune diseases by enhancing the survival of autoreactive B cells. The protein encoded by this gene is a receptor for BAFF and is a type III transmembrane protein containing a single extracellular cysteine-rich domain. It is thought that this receptor is the principal receptor required for BAFF-mediated mature B-cell survival.

Alternative names and synonyms associated with TNFRSF13C

  • tumor necrosis factor receptor superfamily, member 13C (TNFRSF13C)
  • tumor necrosis factor receptor superfamily, member 13c (Tnfrsf13c)
  • tumor necrosis factor receptor superfamily member 13C-like (LOC618516)
  • 2010006P15Rik Protein
  • BAFF-R Protein
  • Baffr Protein
  • Bcmd Protein
  • Bcmd-1 Protein
  • Bcmd1 Protein
  • BROMIX Protein
  • CD268 Protein
  • CVID4 Protein
  • Lvis22 Protein
  • prolixin Protein
  • RGD1560810 Protein
  • TNFRSF13C Protein

Bezeichner auf Proteinebene für TNFRSF13C

tumor necrosis factor receptor superfamily, member 13C , tumor necrosis factor receptor superfamily member 13C , B cell-activating factor receptor , B-cell-activating factor receptor , BAFF receptor , BLyS receptor 3 , B-cell maturation defect 1 , b cell-activating factor receptor

417983 Gallus gallus
500910 Rattus norvegicus
607785 Canis lupus familiaris
618516 Bos taurus
746611 Pan troglodytes
115650 Homo sapiens
72049 Mus musculus
Ausgewählte Anbieter für TNFRSF13C Proteine (TNFRSF13C)
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