anti-RIPK1 (RIPK1) Antikörper

Bezeichnung:
anti-Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 Antikörper (RIPK1)
Auf www.antikoerper-online.de finden Sie aktuell 137 Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Antikörper von 24 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen RIPK1 Proteine (29) und RIPK1 Kits (14) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 191 RIPK1 Produkte verfügbar.
Synonyme:
2400006N03Rik, C9orf12, D330015H01Rik, RGD1311271, Rinp, Rip, Rip1, rIpk1, RP23-83I13.5

Meistgesuchte Reaktivitäten zu anti-RIPK1 (RIPK1) Antikörper

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anti-Rat (Rattus) RIPK1 Antikörper:

anti-Human RIPK1 Antikörper:

anti-Mouse (Murine) RIPK1 Antikörper:

Alle verfügbaren anti-RIPK1 Antikörper

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Am meisten referenzierte anti-RIPK1 Antikörper

  1. Chicken Monoclonal RIPK1 Primary Antibody für IF, IP - ABIN967984 : Takahashi, Tanaka, Brannan, Jenkins, Copeland, Suda, Nagata: Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. in Cell 1994 (PubMed)
    Zeige alle 5 Referenzen für 967984

  2. Human Polyclonal RIPK1 Primary Antibody für ELISA, ICC - ABIN4350584 : Nilsson, Loganathan, Sekiguchi, Matsuba, Hui, Tsubuki, Tanaka, Iwata, Saito, Saido: Aβ secretion and plaque formation depend on autophagy. in Cell reports 2013 (PubMed)
    Zeige alle 3 Referenzen für 4350584

  3. Human Polyclonal RIPK1 Primary Antibody für IHC (p), WB - ABIN657814 : Kim, Ohoka, Okuhira, Sai, Nishimaki-Mogami, Naito: Modulation of RIP1 ubiquitylation and distribution by MeBS to sensitize cancer cells to tumor necrosis factor α-induced apoptosis. in Cancer science 2010 (PubMed)
    Zeige alle 2 Referenzen für 657814

  4. Human Polyclonal RIPK1 Primary Antibody für IHC (fro), IHC (p) - ABIN127073 : Hsu, Huang, Shu, Baichwal, Goeddel: TNF-dependent recruitment of the protein kinase RIP to the TNF receptor-1 signaling complex. in Immunity 1996 (PubMed)
    Zeige alle 2 Referenzen für 127073

  5. Human Polyclonal RIPK1 Primary Antibody für IF (p), IHC (p) - ABIN715016 : Luo, Roy, Xiao, Sun, Liang, Chen, Fu, Sun, Zhu, Ye, Liu: Lycorine induces programmed necrosis in the multiple myeloma cell line ARH-77. in Tumour biology 2014 (PubMed)
    Zeige alle 2 Referenzen für 715016

  6. Human Monoclonal RIPK1 Primary Antibody für IP, WB - ABIN967307 : Stanger, Leder, Lee, Kim, Seed: RIP: a novel protein containing a death domain that interacts with Fas/APO-1 (CD95) in yeast and causes cell death. in Cell 1995 (PubMed)

  7. Cow (Bovine) Polyclonal RIPK1 Primary Antibody für WB - ABIN2792131 : Kurenova, Xu, Yang, Baldwin, Craven, Hanks, Liu, Cance: Focal adhesion kinase suppresses apoptosis by binding to the death domain of receptor-interacting protein. in Molecular and cellular biology 2004 (PubMed)

Weitere Antikörper gegen RIPK1 Interaktionspartner

Human Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Interaktionspartner

  1. UL45 promoted the UL48-RIP1 (zeige UQCRFS1 Antikörper) interaction and re-localization of RIP1 (zeige UQCRFS1 Antikörper) to the UL48-containing virion assembly complex.

  2. we provide evidence that p62 (zeige GTF2H1 Antikörper) is implicated in the activation of NF-kappaB (zeige NFKB1 Antikörper) signaling that is partly dependent on RIP1 (zeige UQCRFS1 Antikörper)

  3. inactivation of RIP1 (zeige UQCRFS1 Antikörper)/RIP3 (zeige RIPK3 Antikörper) resulted in reduction of SOCS1 (zeige SOCS1 Antikörper) protein levels and partial differentiation of AML (zeige RUNX1 Antikörper) cells. AML (zeige RUNX1 Antikörper) cells with inactivated RIP1 (zeige UQCRFS1 Antikörper)/RIP3 (zeige RIPK3 Antikörper) signaling show increased sensitivity to IFN-gamma-induced (zeige SAMHD1 Antikörper) differentiation.

  4. Data show that pan (zeige SUPT6H Antikörper)-caspase (zeige CASP3 Antikörper) inhibitors facilitated 5-fluorouracil (5-FU)-induced necroptosis mediated by secretion of tumor necrosis factor alpha (TNF-alpha (zeige TNF Antikörper)) driven by nuclear factor kappaB (NF-kappaB (zeige NFKB1 Antikörper)) and required RIP1 (zeige UQCRFS1 Antikörper) kinase.

  5. RIPK1 kinase activity is a pertinent therapeutic target to protect liver against excessive cell death in liver diseases.

  6. Ripk1 is directly involved in apoptosis/necroptosis. In osteosarcoma cells( OS) , small interfering RNA against Ripk1 prevented cell death induced by the sequestration of miR (zeige MLXIP Antikörper)-155-5p. Collectively, we show that miR (zeige MLXIP Antikörper)-148a-3p and miR (zeige MLXIP Antikörper)-155-5p are species-conserved deregulated miRNA in OS

  7. RIPK1 collaborates with TRAF2 (zeige TRAF2 Antikörper) to inhibit murine and human hepatocarcinogenesis.

  8. Necroptosis signaling is modulated by the kinase RIPK1 and requires the kinase RIPK3 and the pseudokinase MLKL. (Review)

  9. CYLD (zeige CYLD Antikörper) Promotes TNF-alpha (zeige TNF Antikörper)-Induced Cell Necrosis Mediated by RIP-1 (zeige UQCRFS1 Antikörper) in Human Lung Cancer Cells

  10. TRAIL can enhance RIP1 (zeige UQCRFS1 Antikörper) and c-FLIPL (zeige CFLAR Antikörper) expression in HepG2 cells.

Mouse (Murine) Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1) Interaktionspartner

  1. MK2 (zeige KCNA2 Antikörper)-mediated phosphorylation of RIPK1 serves as a checkpoint within the TNF (zeige TNF Antikörper) signaling pathway that integrates cell survival and cytokine production.

  2. study identifies a novel role for RIPK1 and RIPK3 (zeige RIPK3 Antikörper), a pair of homologous serine/threonine kinases previously implicated in the regulation of necroptosis and pathologic tissue injury, in directing IFN-beta (zeige IFNB1 Antikörper) production in macrophagesges.

  3. this study shows that RIPK1 and RIPK3 (zeige RIPK3 Antikörper) account for acute inflammatory responses induced by lipopolysaccharide in vivo; notably, this regulation does not require exogenous manipulation of caspases

  4. these findings indicate that RIPK1 cooperates with NF-kappaB (zeige NFKB1 Antikörper) signaling to prevent TNFR1 (zeige TNFRSF1A Antikörper)-independent hepatocyte apoptosis and the development of chronic liver disease and cancer, but acts downstream of TNFR1 (zeige TNFRSF1A Antikörper) signaling to promote diethylnitrosamine-induced liver tumorigenesis.

  5. this study reveals a critical kinase-independent platform role for RIPK1 in protecting against TNF (zeige TNF Antikörper)/caspase (zeige CASP3 Antikörper)-dependent apoptosis of hepatocytes in immune-mediated liver injury

  6. Results revealed that RIPK1 and PGAM5 (zeige PGAM5 Antikörper) function independently to exert optimal control of Leishmania replication in the host.

  7. Knocking down receptor-interacting serine/threonine protein kinase 1 (Ripk1) increased both intracellular and extracellular PGRN (zeige GRN Antikörper) protein levels by increasing the translation rate of PGRN (zeige GRN Antikörper) without affecting mRNA levels.

  8. The findings reported here indicate that palmitate induces RIP1/RIP3-dependent necrosis via MLKL-mediated pore formation of RAW 264.7 cells in the plasma membrane, which could provide a new mechanism to explain the link between elevated levels of free fatty acids (FFAs), palmitate in particular, and macrophage death.

  9. The results indicate that RIP1 and MLKL contribute to necroptotic cell death after HCoV-OC43 infection to limit viral replication.

  10. this study reveals a unique response of Kupffer cells against liver ischemia reperfusion, that is, RIP1 (zeige RALBP1 Antikörper)-dependent necrosis, which constitutes a novel mechanism of liver inflammatory immune activation in the pathogenesis of liver ischemia reperfusion injury

RIPK1 Antigen-Profil

Beschreibung des Gens

Serine-threonine kinase which transduces inflammatory and cell-death signals (necroptosis) following death receptors ligation, activation of pathogen recognition receptors (PRRs), and DNA damage. Upon activation of TNFR1 by the TNF-alpha family cytokines, TRADD and TRAF2 are recruited to the receptor. Ubiquitination by TRAF2 via 'Lys-63'-link chains acts as a critical enhancer of communication with downstream signal transducers in the mitogen-activated protein kinase pathway and the NF-kappa-B pathway, which in turn mediate downstream events including the activation of genes encoding inflammatory molecules. Polyubiquitinated protein binds to IKBKG/NEMO, the regulatory subunit of the IKK complex, a critical event for NF-kappa-B activation. Interaction with other cellular RHIM-containing adapters initiates gene activation and cell death. RIPK1 and RIPK3 association, in particular, forms a necroptosis-inducing complex.

Alternative names and synonyms associated with RIPK1

  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (LOC100230522) Antikörper
  • inositol 1,3,4,5,6-pentakisphosphate 2-kinase (Ippk) Antikörper
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (RIPK1) Antikörper
  • receptor (TNFRSF)-interacting serine-threonine kinase 1 (Ripk1) Antikörper
  • RPA interacting protein (Rpain) Antikörper
  • 2400006N03Rik Antikörper
  • C9orf12 Antikörper
  • D330015H01Rik Antikörper
  • RGD1311271 Antikörper
  • Rinp Antikörper
  • Rip Antikörper
  • Rip1 Antikörper
  • rIpk1 Antikörper
  • RP23-83I13.5 Antikörper

Bezeichner auf Proteinebene für RIPK1

receptor (TNFRSF)-interacting serine-threonine kinase 1 , 1,3,4,5,6-pentakisphosphate 2-kinase , inositol polyphosphate kinase 1 , inositol-1,3,4,5,6-pentakisphosphate 2-kinase , inositol-pentakisphosphate 2-kinase , ins(1,3,4,5,6)P5 2-kinase , insP5 2-kinase , RIP-1 , cell death protein RIP , receptor interacting protein , receptor-interacting protein 1 , receptor-interacting serine/threonine-protein kinase 1 , serine/threonine-protein kinase RIP , RPA interacting protein delta 2 , RPA interacting protein epsilon , RPA-interacting protein

GENE ID SPEZIES
100230522 Taeniopygia guttata
306808 Rattus norvegicus
8737 Homo sapiens
504727 Bos taurus
100524751 Sus scrofa
19766 Mus musculus
306886 Rattus norvegicus
69723 Mus musculus
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