anti-IRAK4 (IRAK4) Antikörper

Bezeichnung:
anti-Interleukin-1 Receptor-Associated Kinase 4 Antikörper (IRAK4)
Auf www.antikoerper-online.de finden Sie aktuell 203 Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Antikörper von 28 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IRAK4 Proteine (13) und IRAK4 Kits (9) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 235 IRAK4 Produkte verfügbar.
Synonyme:
8430405M07Rik, 9330209D03Rik, IPD1, IRAK-4, irak4, ny-ran-64, NY-REN-64, REN64, zgc:55553
Alle Antikörper anzeigen Gen GeneID UniProt
IRAK4 51135 Q9NWZ3
IRAK4 266632 Q8R4K2
IRAK4 300177  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-IRAK4 (IRAK4) Antikörper

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anti-Human IRAK4 Antikörper:

anti-Mouse (Murine) IRAK4 Antikörper:

anti-Rat (Rattus) IRAK4 Antikörper:

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Am meisten referenzierte anti-IRAK4 Antikörper

  1. Human Polyclonal IRAK4 Primary Antibody für EIA, IHC (p) - ABIN401362 : Branlant, Krol, Ebel: Characterization of the Escherichia coli 23S Ribosomal RNA region associated with ribosomal protein L1. Evidence for homologies with the 5'-end region of the L11 operon. in Nucleic acids research 1981 (PubMed)
    Zeige alle 7 Referenzen für 401362

  2. Human Polyclonal IRAK4 Primary Antibody für EIA, WB - ABIN952943 : McDonald, Goldman, Gomez-Duarte, Issekutz, Kumararatne, Doffinger, Geha: Impaired T-cell receptor activation in IL-1 receptor-associated kinase-4-deficient patients. in The Journal of allergy and clinical immunology 2010 (PubMed)
    Zeige alle 5 Referenzen für 952943

  3. Human Polyclonal IRAK4 Primary Antibody für WB - ABIN656802 : Silva, Blanton, Parrado, Melo, Morato, Reis, Dias, Castro, Vasconcelos, Goddard, Barreto, Reis, Teixeira: Dengue hemorrhagic fever is associated with polymorphisms in JAK1. in European journal of human genetics : EJHG 2010 (PubMed)
    Zeige alle 2 Referenzen für 656802

  4. Human Polyclonal IRAK4 Primary Antibody für WB - ABIN658069 : Erdman, Cosio, Helmers, Gowda, Grinstein, Kain: CD36 and TLR interactions in inflammation and phagocytosis: implications for malaria. in Journal of immunology (Baltimore, Md. : 1950) 2009 (PubMed)
    Zeige alle 2 Referenzen für 658069

  5. Human Monoclonal IRAK4 Primary Antibody für FACS, IHC - ABIN969218 : Pathak, De Souza, Salte, Wiker, Asjö: HIV induces both a down-regulation of IRAK-4 that impairs TLR signalling and an up-regulation of the antibiotic peptide dermcidin in monocytic cells. in Scandinavian journal of immunology 2009 (PubMed)
    Zeige alle 2 Referenzen für 969218

  6. Human Polyclonal IRAK4 Primary Antibody für ELISA, IHC (p) - ABIN250402 : Lye, Mirtsos, Suzuki, Suzuki, Yeh: The role of interleukin 1 receptor-associated kinase-4 (IRAK-4) kinase activity in IRAK-4-mediated signaling. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen IRAK4 Interaktionspartner

Human Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Interaktionspartner

  1. the polymorphisms in TLR-MyD88 (zeige MYD88 Antikörper)-NF-kappaB (zeige NFKB1 Antikörper) signaling pathway confer genetic susceptibility to Type 2 diabetes mellitus and diabetic nephropathy.

  2. data show that in pericytes, MyD88 (zeige MYD88 Antikörper) and IRAK4 are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  3. Data suggest that, in monocytes and macrophages, the interleukin-1B- (IL1B (zeige IL1B Antikörper))-stimulated trans-autophosphorylation of IRAK4 is initiated by MYD88- (myeloid differentiation primary response gene 88 (zeige MYD88 Antikörper))-induced dimerization of IRAK4. In contrast, IRAK1 (interleukin-1 receptor-associated kinase 1 (zeige IRAK1 Antikörper)) is inactive in unstimulated monocytes/macrophages and is converted to an active protein kinase (zeige CDK7 Antikörper) in response to IL1B (zeige IL1B Antikörper).

  4. IRAK4 - Gene involved in innate immunity that have been associated with Chronic Rhinosinusitis.

  5. The estimated prevalence of IRAK4 gene polymorphism found in a Portuguese Caucasian population was 26.8 % (CI 95%) [20.1, 34.7 %]. A model to predict the inflammatory response in the maxillary sinus in the presence etiological factors of dental origin was constructed.

  6. This is the first study to show an association between single nucleotide polymorphisms in IRAK1 (zeige IRAK1 Antikörper), IRAK4 and MyD88 (zeige MYD88 Antikörper), and the presence of severe invasive pneumococcal disease.

  7. Src (zeige SRC Antikörper), Syk (zeige SYK Antikörper), IRAK1 (zeige IRAK1 Antikörper), and IRAK4 have roles in anti-inflammatory responses mediated by dietary flavonoid Kaempferol

  8. findings suggest that rare, functional variants in MYD88, IRAK4 or IKBKG do not significantly contribute to IPD susceptibility in adults at the population level

  9. High mRNA levels of IRAK1 (zeige IRAK1 Antikörper) and IRAK4 correlated with VKH disease activity.

  10. Studies indicate that interleukin-1 receptor-associated kinase 4 protein (IRAK4), a serine/threonine kinase, plays a key role in both inflammation and oncology diseases.

Mouse (Murine) Interleukin-1 Receptor-Associated Kinase 4 (IRAK4) Interaktionspartner

  1. data show that in pericytes, MyD88 (zeige MYD88 Antikörper) and IRAK4 are key regulators of 2 major injury responses: inflammatory and fibrogenic.

  2. IRAK4 kinase activity contributes to murine lupus and could represent a new therapeutic target.

  3. Data demonstrate that IRAK-4 is essential for innate and adaptive immunity and necessary for efficient control of mycobacterial infections.

  4. Suppression of IRAK1 (zeige IRAK1 Antikörper) or IRAK4 Catalytic Activity, but Not Type 1 IFN Signaling, Prevents Lupus Nephritis in Mice Expressing a Ubiquitin Binding-Defective Mutant of ABIN1 (zeige TNIP1 Antikörper)

  5. PMA treatment during a vulnerable period can alter brain development. IL-18 and IRAK-4 appear to be important for the development of PMA induced injury.

  6. enforced expression of miR (zeige MLXIP Antikörper)-302b or IRAK4 siRNA silencing inhibits downstream NF-kappaB (zeige NFKB1 Antikörper) signalling and airway leukocyte infiltration, thereby alleviating lung injury and increasing survival in P. aeruginosa-infected mice.

  7. Our results demonstrate that osteoclasts and FBGCs are reciprocally regulated and identify IRAK4 as a potential therapeutic target to inhibit stimulated osteoclastogenesis and rescue inhibited FBGC formation

  8. Suggest FC-99 is a potential therapeutic molecule that alleviated experimental sepsis by directly inhibiting IRAK4 activation.

  9. MiR (zeige MLXIP Antikörper)-93 inhibits IRAK4 expression by binding directly to the 3'-UTR (zeige UTS2R Antikörper) of IRAK4.

  10. Intact IRAK4 function inhibited heart-specific migration of bone-marrow-derived CCR5 (zeige CCR5 PLURAL_@2304@)(+) cells.

IRAK4 Antigen-Profil

Beschreibung des Gens

This gene encodes a kinase that activates NF-kappaB in both the Toll-like receptor (TLR) and T-cell receptor (TCR) signaling pathways. The protein is essential for most innate immune responses. Mutations in this gene result in IRAK4 deficiency and recurrent invasive pneumococcal disease. Multiple transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with IRAK4

  • interleukin-1 receptor-associated kinase 4 (IRAK4) Antikörper
  • interleukin-1 receptor-associated kinase 4 (irak4) Antikörper
  • Interleukin-1 receptor-associated kinase 4 (irak4) Antikörper
  • interleukin-1 receptor-associated kinase 4 (LOC100227974) Antikörper
  • interleukin-1 receptor-associated kinase 4 (Irak4) Antikörper
  • 8430405M07Rik Antikörper
  • 9330209D03Rik Antikörper
  • IPD1 Antikörper
  • IRAK-4 Antikörper
  • irak4 Antikörper
  • ny-ran-64 Antikörper
  • NY-REN-64 Antikörper
  • REN64 Antikörper
  • zgc:55553 Antikörper

Bezeichner auf Proteinebene für IRAK4

interleukin-1 receptor-associated kinase 4 , interleukin-1 receptor-associated kinase 4-like , Interleukin-1 receptor-associated kinase 4 , renal carcinoma antigen NY-REN-64 , NY-REN-64 antigen , interleukin-1 receptor associated kinase 4

GENE ID SPEZIES
100054848 Equus caballus
100216438 Ovis aries
100019202 Monodelphis domestica
100447243 Pongo abelii
100469127 Ailuropoda melanoleuca
100528915 Ictalurus punctatus
393132 Danio rerio
417796 Gallus gallus
700568 Macaca mulatta
733738 Xenopus (Silurana) tropicalis
100196744 Salmo salar
100227974 Taeniopygia guttata
100402978 Callithrix jacchus
100602648 Nomascus leucogenys
51135 Homo sapiens
266632 Mus musculus
466962 Pan troglodytes
486601 Canis lupus familiaris
100127166 Sus scrofa
533692 Bos taurus
300177 Rattus norvegicus
100341605 Oryctolagus cuniculus
Ausgewählte Anbieter für anti-IRAK4 (IRAK4) Antikörper
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