anti-ARHGEF1 (ARHGEF1) Antikörper

Bezeichnung:
anti-rho Guanine Nucleotide Exchange Factor (GEF) 1 Antikörper (ARHGEF1)
Auf www.antikoerper-online.de finden Sie aktuell 60 rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) Antikörper von 15 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen ARHGEF1 Proteine (5) und ARHGEF1 Kits (3) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 76 ARHGEF1 Produkte verfügbar.
Synonyme:
ARHGEF1, cb473, GEF1, Lbcl2, Lsc, P115-RHOGEF, SUB1.5, zgc:158261
Alle Antikörper anzeigen Gen GeneID UniProt
ARHGEF1 9138 Q92888
ARHGEF1 16801 Q61210
ARHGEF1 60323  

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-ARHGEF1 (ARHGEF1) Antikörper

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anti-Human ARHGEF1 Antikörper:

anti-Mouse (Murine) ARHGEF1 Antikörper:

anti-Rat (Rattus) ARHGEF1 Antikörper:

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Am meisten referenzierte anti-ARHGEF1 Antikörper

  1. Human Polyclonal ARHGEF1 Primary Antibody für EIA, WB - ABIN950494 : Loirand, Pacaud: [The exchange factor Arhgef1: a new target in hypertension]. in Médecine sciences : M/S 2010 (PubMed)
    Zeige alle 5 Referenzen für 950494

  2. Human Polyclonal ARHGEF1 Primary Antibody für WB - ABIN2801964 : Hart, Sharma, elMasry, Qiu, McCabe, Polakis, Bollag: Identification of a novel guanine nucleotide exchange factor for the Rho GTPase. in The Journal of biological chemistry 1996 (PubMed)
    Zeige alle 3 Referenzen für 2801964

  3. Human Monoclonal ARHGEF1 Primary Antibody für IF, ELISA - ABIN522597 : Zizer, Beilke, Bäuerle, Schilling, Möhnle, Adler, Fischer, Wagner: Loss of Lsc/p115 protein leads to neuronal hypoplasia in the esophagus and an achalasia-like phenotype in mice. in Gastroenterology 2010 (PubMed)

  4. Human Polyclonal ARHGEF1 Primary Antibody für WB - ABIN658789 : Slattum, McGee, Rosenblatt: P115 RhoGEF and microtubules decide the direction apoptotic cells extrude from an epithelium. in The Journal of cell biology 2009 (PubMed)

  5. Human Polyclonal ARHGEF1 Primary Antibody für ICC, IF - ABIN4281534 : Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells. in Nature methods 2013 (PubMed)

Weitere Antikörper gegen ARHGEF1 Interaktionspartner

Human rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) Interaktionspartner

  1. Data suggest that MCP1/CCL2 (zeige CCL2 Antikörper) induces activation/tyrosine phosphorylation of ARHGEF1/p115-RhoGEF and up-regulates RAC1 signaling in vascular smooth muscle cells (VSMCs); ARHGEF1 inhibition suppresses MCP1 (zeige CCL2 Antikörper)-induced VSMC migration and proliferation. (ARHGEF1 = Rho guanine nucleotide exchange factor 1; RAC1 = Rac (zeige AKT1 Antikörper) family small GTPase (zeige RACGAP1 Antikörper) 1; CCL2 (zeige CCL2 Antikörper) = C-C motif chemokine ligand 2 (zeige CXCL2 Antikörper))

  2. Data indicate that the crystal structure of PDZ-RhoGEF (zeige ARHGEF11 Antikörper) PDZ domain (zeige INADL Antikörper) in complex with the CXC chemokine receptor (zeige CXCR4 Antikörper) 2 (CXCR2 (zeige CXCR2 Antikörper)) C-terminal PDZ (zeige INADL Antikörper) binding motif.

  3. We have reported here for the first time a reduced activity of both Rac1 and Cdc42 (zeige CDC42 Antikörper) in human pheochromocytoma resection as well as tumor-associated expression changes of FARP1 (zeige FARP1 Antikörper), ARHGEF1, and ARHGAP36 (zeige ARHGAP36 Antikörper)

  4. contactin-1 (zeige CNTN1 Antikörper) displayed the ability to phosphorylate the RhoA (zeige RHOA Antikörper) activator p115 RhoGEF

  5. The novel role for p115RhoGEF in regulation of epithelial plasticity is dependent on Rho-DRF (zeige MPO Antikörper) signaling module.

  6. Regulated localization is sufficient for hormonal control of regulator of G protein signaling homology Rho guanine nucleotide exchange factors (RH-RhoGEFs).

  7. Modification of p115RhoGEF at Serine(330) regulates its RhoGEF (zeige ARHGEF11 Antikörper) activity.

  8. The action of DOCK7 (zeige DOCK7 Antikörper) in vivo may involve the coordinated integration of Cdc42 (zeige CDC42 Antikörper)/Rac1 signaling in the context of the membrane recruitment of a DOCK7 (zeige DOCK7 Antikörper) guanine nucleotide exchange factor (zeige RASGRF1 Antikörper) (GEF (zeige SLC2A4RG Antikörper)) complex.

  9. High GEF1 expression is associated with metastasis of pancreatic cancer.

  10. Activation of p115-RhoGEF requires direct association of Galpha13 (zeige GNA13 Antikörper) and the Dbl (zeige MCF2 Antikörper) homology domain.

Mouse (Murine) rho Guanine Nucleotide Exchange Factor (GEF) 1 (ARHGEF1) Interaktionspartner

  1. these findings reveal that Arhgef1 functions as a negative regulator of neurite outgrowth through regulating RhoA-cofilin pathway and actin dynamics.

  2. Upon beta(2)AR activation, both betaArrestin2 and p115RhoGEF translocate to the plasma membrane, with concomitant activation of RhoA (zeige RHOA Antikörper) and formation of focal adhesions and stress fibers.

  3. Thromboxane receptor (zeige TBXA2R Antikörper) signaling is required for fibronectin (zeige FN1 Antikörper)-induced matrix metalloproteinase 9 (zeige MMP9 Antikörper) production by human and murine macrophages and is attenuated by the Arhgef1 molecule.

  4. Results show that PKC-alpha phosphorylation of p115RhoGEF mediates TNF-alpha signaling to RhoA, and that this plays a critical role in signaling F-actin rearrangement and barrier dysfunction in endothelial cells.

  5. lsc/p115 (zeige ARHGAP4 Antikörper) deficiency results in impaired neuronal innervation and in motor dysfunction recapitulating several aspects of esophageal achalasia.

  6. These data demonstrate that Arhgef1 regulates alpha5beta1-mediated MMP expression by macrophages and that loss of Arhgef1 by leukocytes leads to pulmonary pathology.

  7. results show that control of RhoA (zeige RHOA Antikörper) signaling through Arhgef1 is central to the development of angiotensin II-dependent hypertension and identify Arhgef1 as a potential target for the treatment of hypertension

  8. First, Lsc homo-oligomerizes and is negatively regulated through domains in its C terminus; and second, functionally distinct isoforms of Lsc lacking these domains are present in the spleen.

  9. Lsc is essential for mediating TXA(2 (zeige TBXA2R Antikörper) )signaling involved in apoptosis and actin organization and suggest that TXA(2 (zeige TBXA2R Antikörper)) regulates thymic cellularity via Lsc.

  10. Lsc is a RhoA (zeige RHOA Antikörper) guanine nucleotide exchange factor (zeige ARHGEF12 Antikörper) that binds the heterotrimeric G-protein alpha (zeige GNAO1 Antikörper)-subunits, Galpha12 (zeige GNA12 Antikörper) and Galpha13 (zeige GNA13 Antikörper).

ARHGEF1 Antigen-Profil

Beschreibung des Gens

Rho GTPases play a fundamental role in numerous cellular processes that are initiated by extracellular stimuli that work through G protein coupled receptors. The encoded protein may form complex with G proteins and stimulate Rho-dependent signals. Multiple alternatively spliced transcript variants have been found for this gene, but the full-length nature of some variants has not been defined.

Alternative names and synonyms associated with ARHGEF1

  • Rho guanine nucleotide exchange factor (GEF) 1a (arhgef1a) Antikörper
  • Rho guanine nucleotide exchange factor (GEF) 1 (ARHGEF1) Antikörper
  • Rho guanine nucleotide exchange factor (GEF) 1 (arhgef1) Antikörper
  • Rho guanine nucleotide exchange factor (GEF) 1 (Arhgef1) Antikörper
  • ARHGEF1 Antikörper
  • cb473 Antikörper
  • GEF1 Antikörper
  • Lbcl2 Antikörper
  • Lsc Antikörper
  • P115-RHOGEF Antikörper
  • SUB1.5 Antikörper
  • zgc:158261 Antikörper

Bezeichner auf Proteinebene für ARHGEF1

rho guanine nucleotide exchange factor (GEF) 1 , Rho guanine nucleotide exchange factor (GEF) 1 , rho guanine nucleotide exchange factor 1-like , 115 kDa guanine nucleotide exchange factor , 115-kD protein , Lsc homolog , p115RhoGEF , rho guanine nucleotide exchange factor 1 , lbc's second cousin , lymphoid blast crisis like 2 , lymphoid blast crisis-like 2

GENE ID SPEZIES
368266 Danio rerio
513377 Bos taurus
722198 Macaca mulatta
100037905 Xenopus (Silurana) tropicalis
100477081 Ailuropoda melanoleuca
100581841 Nomascus leucogenys
9138 Homo sapiens
16801 Mus musculus
60323 Rattus norvegicus
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