anti-CYP24A1 (CYP24A1) Antikörper

Bezeichnung:
anti-Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 Antikörper (CYP24A1)
Auf www.antikoerper-online.de finden Sie aktuell 89 Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen CYP24A1 Kits (15) und CYP24A1 Proteine (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 118 CYP24A1 Produkte verfügbar.
Synonyme:
24-OHase, 25-hydroxyvitaminD324-hydroxylase, CP24, CP450CC24, Cyp24, HCAI, P450-CC24, VITD12

Meistgesuchte Reaktivitäten zu anti-CYP24A1 (CYP24A1) Antikörper

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anti-Human CYP24A1 Antikörper:

anti-Mouse (Murine) CYP24A1 Antikörper:

anti-Rat (Rattus) CYP24A1 Antikörper:

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Am meisten referenzierte anti-CYP24A1 Antikörper

  1. Human Polyclonal CYP24A1 Primary Antibody für ICC, IF - ABIN4301730 : Smolders, Schuurman, van Strien, Melief, Hendrickx, Hol, van Eden, Luchetti, Huitinga: Expression of vitamin D receptor and metabolizing enzymes in multiple sclerosis-affected brain tissue. in Journal of neuropathology and experimental neurology 2013 (PubMed)

  2. Human Monoclonal CYP24A1 Primary Antibody für ELISA, WB - ABIN514852 : Helvig, Cuerrier, Hosfield, Ireland, Kharebov, Kim, Ramjit, Ryder, Tabash, Herzenberg, Epps, Petkovich: Dysregulation of renal vitamin D metabolism in the uremic rat. in Kidney international 2010 (PubMed)

  3. Human Polyclonal CYP24A1 Primary Antibody für EIA, IHC (p) - ABIN453594 : Okuda, Usui, Ohyama: Recent progress in enzymology and molecular biology of enzymes involved in vitamin D metabolism. in Journal of lipid research 1995 (PubMed)

  4. Human Polyclonal CYP24A1 Primary Antibody für ELISA, WB - ABIN4301729 : Shen, Bielak, Ferguson, Streeten, Yerges-Armstrong, Liu, Post, OConnell, Hixson, Kardia, Sun, Jhun, Wang, Mehta, Li, Koller, Hakonarson, Keating, Rader, Shuldiner, Peyser, Reilly, Mitchell: Association of the vitamin D metabolism gene CYP24A1 with coronary artery calcification. in Arteriosclerosis, thrombosis, and vascular biology 2010 (PubMed)

  5. Human Polyclonal CYP24A1 Primary Antibody für ELISA, WB - ABIN1534377 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)

Weitere Antikörper gegen CYP24A1 Interaktionspartner

Human Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) Interaktionspartner

  1. Uremic serum increased the intracellular expression of IL-6 (zeige IL6 Antikörper), IFN-gamma (zeige IFNG Antikörper), TLR7 (zeige TLR7 Antikörper), TLR9 (zeige TLR9 Antikörper), VDR (zeige CYP27B1 Antikörper), CYP27b1 (zeige CYP27B1 Antikörper) and CYP24a1

  2. Biallelic mutations in CYP24A1 or SLC34A1 (zeige SLC34A1 Antikörper) were associated with infantile idiopathic hypercalcemia with vitamin D hypersensitivity

  3. CYP24A1 association with the susceptibility of esophageal squamous cell carcinoma in a Northern Chinese population.

  4. CYP24A1 was expressed in a >2-fold higher fraction of spermatozoa from normal than infertile men.

  5. Our results indicate that CYP24A1, central in the degradation of the physiologically active 1,25[OH]2D, is important in the association of lower levels of 25[OH]D and increased risk of SLE.

  6. Findings offer direct evidence that Cyp24a1 functions as an oncogene (zeige RAB1A Antikörper) in PTC (zeige F9 Antikörper), where its overexpression activates multiple signaling cascades to promote malignant progression.

  7. The aim of the present study was to investigate the mRNA expression levels of the CYP24A1 and CYP27B1 (zeige CYP27B1 Antikörper) genes in malignant and normal breast tissues. The results demonstrated that the mRNA expression of CYP27B1 (zeige CYP27B1 Antikörper) was downregulated in the tumor tissues, compared with the adjacent normal tissues (P<0.01), whereas the mRNA expression of CYP24A1 was significantly upregulated in the tumor tissues (P<0.01).

  8. suppression of vitamin D metabolism following knockdown of CYP24A1 significantly reduced tumor growth in vivo. These data provide substantial evidence for a pro-survival and stimulatory oncogenic effect of CYP24A1 in breast carcinoma cells

  9. confirms that CYP24A1 plays a causal role in some but not all cases of IIH (64%); (2) expands the spectrum of known CYP24A1 pathogenic mutations; (3) describes 2 hotspots detected in 50% of all Italian cases; and (4) emphasizes the importance of recognition and genetic diagnosis of CYP24A1 defects in infantile as well as adult hypercalcemia

  10. Suggest Cyp24a1 promoter SNP rs2248359 is associated with severe atopic dermatitis.

Mouse (Murine) Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1) Interaktionspartner

  1. results link CYP24 activity to the pathophysiology of FGF23 (zeige FGF23 Antikörper)-dependent renal phosphate wasting states and implicate pharmacologic CYP24 inhibition as a therapeutic adjunct for their treatment.

  2. Gsalpha is required in proximal tubules for suppressing renal vitamin D 24-hydroxylase mRNA levels and for maintaining normal serum 1,25(OH)2D.

  3. Data suggest that control of CYP24A1 increase during diabetes has a beneficial effect on senescence induction and caspase-3 (zeige CASP3 Antikörper) increased expression.

  4. the mechanism through which 1,25(OH)(2)D(3) induces the CYP24A1 enzyme

  5. The expression of vitamin D 24-hydroxylase gene was directly regulated by serum calcium rather than 25-hydroxyvitamin D 1 alpha-hydroxylase.

  6. Results show that Inhibition of 24-OHase activity modulates serum calcitriol PK in normal C3H/HeJ mice.

  7. Cyp24a1 deficiency delays fracture repair and strongly suggest that vitamin D metabolites hydroxylated at position 24, such as 24,25(OH)2D3, play an important role in the mechanisms leading to normal fracture hea (zeige TTC7A Antikörper)

  8. 1,25(OH)2D is the preferred substrate for CYP24 in murine kidney mitochondria.

  9. findings demonstrate that regulation of both the 25-hydroxyvitamin D-1 alpha-hydroxylase and 25-hydroxyvitamin D-24-hydroxylase genes by phosphorus is disordered in hypophosphatemic mice at the level of renal mRNA expression

  10. the absence of CYP24A1 or vitamin D receptor (zeige VDR Antikörper) retards catabolism of 1alpha,25(OH)2D3 and 25(OH)D3

CYP24A1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with CYP24A1

  • cytochrome P450, family 24, subfamily A, polypeptide 1 (CYP24A1) Antikörper
  • cytochrome P450, family 24, subfamily a, polypeptide 1 (Cyp24a1) Antikörper
  • 24-OHase Antikörper
  • 25-hydroxyvitaminD324-hydroxylase Antikörper
  • CP24 Antikörper
  • CP450CC24 Antikörper
  • Cyp24 Antikörper
  • HCAI Antikörper
  • P450-CC24 Antikörper
  • VITD12 Antikörper

Bezeichner auf Proteinebene für CYP24A1

1,25-@dihydroxyvitamin D3 24-hydroxylase , 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial , 24-OHase , cytochrome P450 24A1 , cytochrome P450, subfamily XXIV (vitamin D 24-hydroxylase) , cytochrome P450-CC24 , exo-mitochondrial protein , vitamin D 24-hydroxylase , vitamin D(3) 24-hydroxylase , 25-hydroxyvitamin D-24-hydroxylase , cytochrome P450, 24 , cytochrome P450, 24a1 , 24R-Ohase , 25-hydroxyvitamin D3 24-hydroxylase , Cytochrom P450 (25-hydroxyvitamin D24-hydroxylase) , P450-CC24 , cytochrome P450, subfamily 24 , 25-hydroxyvitamin D3-24-hydroxylase

GENE ID SPEZIES
1591 Homo sapiens
13081 Mus musculus
25279 Rattus norvegicus
395827 Gallus gallus
485935 Canis lupus familiaris
397145 Sus scrofa
540080 Bos taurus
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