CYP24A1 Antikörper (Center)
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- Target Alle CYP24A1 Antikörper anzeigen
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
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Bindungsspezifität
- Center
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Reaktivität
- Human, Maus
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Wirt
- Kaninchen
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Klonalität
- Polyklonal
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Konjugat
- Dieser CYP24A1 Antikörper ist unkonjugiert
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Applikation
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
- Kreuzreaktivität
- Maus, Ratte (Rattus)
- Kreuzreaktivität (Details)
- mouse (87 %), Rat (88 %)
- Produktmerkmale
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Rabbit Polyclonal antibody to CYP24A1 (cytochrome P450, family 24, subfamily A, polypeptide 1)
CYP24A1 antibody - Aufreinigung
- Purified by antigen-affinity chromatography.
- Immunogen
- Recombinant protein encompassing a sequence within the center region of human CYP24A1. The exact sequence is proprietary.
- Isotyp
- IgG
- Top Product
- Discover our top product CYP24A1 Primärantikörper
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- Applikationshinweise
- Suggested dilution Reference IHC (Formalin-fixed paraffin-embedded sections) 1:100-1:1000* Western blot 1:500-1:3000* Not tested in other applications. *Optimal dilutions/concentrations should be determined by the researcher.Suggested dilutionReferenceIHC (Formalin-fixed paraffin-embedded sections)1:100-1:1000* Western blot1:500-1:3000*
- Kommentare
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Positive Control: 293T , A431 , H1299 , HeLaS3 , HepG2 , Molt-4 , Raji
- Beschränkungen
- Nur für Forschungszwecke einsetzbar
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- Format
- Liquid
- Konzentration
- 1 mg/mL
- Buffer
- 0.1M Tris, 0.1M Glycine, 10 % Glycerol ( pH 7). 0.01 % Thimerosal was added as a preservative.
- Konservierungsmittel
- Thimerosal (Merthiolate)
- Vorsichtsmaßnahmen
- This product contains Thimerosal (Merthiolate): a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Lagerung
- -20 °C
- Informationen zur Lagerung
- Keep as concentrated solution. Aliquot and store at -20°C or below. Avoid multiple freeze-thaw cycles.
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- Target
- CYP24A1 (Cytochrome P450, Family 24, Subfamily A, Polypeptide 1 (CYP24A1))
- Andere Bezeichnung
- CYP24A1 (CYP24A1 Produkte)
- Synonyme
- CP24 antikoerper, CYP24 antikoerper, HCAI antikoerper, P450-CC24 antikoerper, 24-OHase antikoerper, Cyp24 antikoerper, 25-hydroxyvitaminD324-hydroxylase antikoerper, VITD12 antikoerper, CP450CC24 antikoerper, cytochrome P450 family 24 subfamily A member 1 antikoerper, cytochrome P450, family 24, subfamily a, polypeptide 1 antikoerper, cytochrome P450, family 24, subfamily A, polypeptide 1 antikoerper, CYP24A1 antikoerper, Cyp24a1 antikoerper
- Hintergrund
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This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This mitochondrial protein initiates the degradation of 1,25-dihydroxyvitamin D3, the physiologically active form of vitamin D3, by hydroxylation of the side chain. In regulating the level of vitamin D3, this enzyme plays a role in calcium homeostasis and the vitamin D endocrine system. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Cellular Localization: Mitochondrion - Molekulargewicht
- 59 kDa
- Gen-ID
- 1591
- Pathways
- Metabolism of Steroid Hormones and Vitamin D
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