anti-SIRT1 (SIRT1) Antikörper

anti-Sirtuin 1 Antikörper (SIRT1)
Auf finden Sie aktuell 330 Sirtuin 1 (SIRT1) Antikörper von 37 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SIRT1 Kits (44) und SIRT1 Proteine (18) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 399 SIRT1 Produkte verfügbar.
AA673258, SIR2, Sir2a, Sir2alpha, sir2l1, sirtuin, sirtuin 1
Alle Antikörper anzeigen Gen GeneID UniProt
SIRT1 93759 Q923E4
SIRT1 23411 Q96EB6
SIRT1 309757  

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Meistgesuchte Reaktivitäten zu anti-SIRT1 (SIRT1) Antikörper

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anti-Mouse (Murine) SIRT1 Antikörper:

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Am meisten referenzierte anti-SIRT1 Antikörper

  1. Cow (Bovine) Polyclonal SIRT1 Primary Antibody für WB - ABIN2779607 : Solomon, Pasupuleti, Xu, McDonagh, Curtis, DiStefano, Huber: Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage. in Molecular and cellular biology 2005 (PubMed)
    Zeige alle 6 Referenzen für 2779607

  2. Human Monoclonal SIRT1 Primary Antibody für WB - ABIN1882053 : Vaziri, Dessain, Ng Eaton, Imai, Frye, Pandita, Guarente, Weinberg: hSIR2(SIRT1) functions as an NAD-dependent p53 deacetylase. in Cell 2001 (PubMed)
    Zeige alle 5 Referenzen für 1882053

  3. Human Polyclonal SIRT1 Primary Antibody für IF (p), IHC (p) - ABIN729853 : Mohan, Kumar, Lackner, Alvarez: Dysregulated miR-34a-SIRT1-acetyl p65 axis is a potential mediator of immune activation in the colon during chronic simian immunodeficiency virus infection of rhesus macaques. in Journal of immunology (Baltimore, Md. : 1950) 2014 (PubMed)
    Zeige alle 3 Referenzen für 729853

  4. Human Monoclonal SIRT1 Primary Antibody für ICC, FACS - ABIN969396 : Xie, Park, Kim, Hwang, Oh, Park, Shong, Lee, Choi: Transcriptional corepressor SMILE recruits SIRT1 to inhibit nuclear receptor estrogen receptor-related receptor gamma transactivation. in The Journal of biological chemistry 2009 (PubMed)
    Zeige alle 2 Referenzen für 969396

  5. Human Monoclonal SIRT1 Primary Antibody für ICC, IF - ABIN2668278 : Rajendran, Kidane, Yu, Dashwood, Bisson, Löhr, Ho, Williams, Dashwood: HDAC turnover, CtIP acetylation and dysregulated DNA damage signaling in colon cancer cells treated with sulforaphane and related dietary isothiocyanates. in Epigenetics 2013 (PubMed)
    Zeige alle 2 Referenzen für 2668278

  6. Mouse (Murine) Polyclonal SIRT1 Primary Antibody für ELISA, WB - ABIN185702 : Chen, Steele, Lindquist, Guarente: Increase in activity during calorie restriction requires Sirt1. in Science (New York, N.Y.) 2005 (PubMed)
    Zeige alle 2 Referenzen für 185702

  7. Human Polyclonal SIRT1 Primary Antibody für IF (p), IHC (p) - ABIN745658 : Suzuki, Bartlett: Sirtuin1 and autophagy protect cells from fluoride-induced cell stress. in Biochimica et biophysica acta 2014 (PubMed)
    Zeige alle 2 Referenzen für 745658

  8. Human Monoclonal SIRT1 Primary Antibody für ELISA, FACS - ABIN4353901 : Lo Iacono, Visco-Comandini, Valzania, Viscomi, Coviello, Giampà, Roscini, Bisicchia, Siracusano, Troisi, Puglisi-Allegra, Carola: Adversity in childhood and depression: linked through SIRT1. in Translational psychiatry 2015 (PubMed)

Weitere Antikörper gegen SIRT1 Interaktionspartner

Rabbit Sirtuin 1 (SIRT1) Interaktionspartner

  1. Our findings revealed a novel regulatory mechanism of innate immunity by SIRT1.

  2. SIRT1 signaling pathway may be targeted for therapeutic intervention in flexor tendon injury.

Mouse (Murine) Sirtuin 1 (SIRT1) Interaktionspartner

  1. Obesity-linked phosphorylation of SIRT1 inhibits its function and promotes pathological symptoms of nonalcoholic fatty liver disease. Ser-164 was identified as a major serine phosphorylation site in SIRT1 in obese, but not lean, mice, and this phosphorylation was catalyzed by casein kinase 2.

  2. SIRT1 promotes early-onset AHL (zeige CDH23 Antikörper) through suppressing FOXO3a (zeige FOXO3 Antikörper)-mediated oxidative stress resistance in the cochlea of C57BL/6 mice.

  3. In analyses of intestinal tissues, colitis induction, and gut (zeige GUSB Antikörper) microbiota in mice with intestinal epithelial disruption of SIRT1, we found this protein to prevent intestinal inflammation by regulating the gut (zeige GUSB Antikörper) microbiota.

  4. this study shows that SIRT1-dependent differentiation of Th9 cells confers protection against tumors and contributes to allergic airway inflammation

  5. SIRT1 interacts with and promotes the transactivation potential of RUNX2 (zeige RUNX2 Antikörper).

  6. Sirt1 might be directly involved in spermiogenesis in germ cells but not in steroidogenic cells. Germ cell-specific Sirt1 knockout mice were almost completely infertile; the early mitotic and meiotic progression of germ cells in spermatogenesis were not obviously affected after Sirt1 depletion, but subsequent spermiogenesis was disrupted by a defect in acrosome biogenesis.

  7. Sirt1 significantly reduced the levels of raptor (zeige RPTOR Antikörper) and inactivated mammalian target of rapamycin (mTOR (zeige FRAP1 Antikörper))C1 signal by interacting with Akt2 (zeige AKT2 Antikörper).

  8. These findings indicate that SIRT1 is a key regulator of macrophage self-renewal that integrates cell cycle and longevity pathways.

  9. Sirt1 deacetylates p65 (zeige NFkBP65 Antikörper) and compromises NF-kappaB (zeige NFKB1 Antikörper) activity in hepatocytes.

  10. the roles of CTSB (zeige CTSB Antikörper)/S and SIRT1 in the regulation of hepatic inflammation using primary parenchymal and non-parenchymal hepatic cell types and cell lines.

Human Sirtuin 1 (SIRT1) Interaktionspartner

  1. Phosphorylated S164-SIRT1 and Casein Kinase 2 levels were also highly elevated in liver samples of nonalcoholic fatty liver disease patients and correlated with disease severity.

  2. Our data suggest that the p53 (zeige TP53 Antikörper)-dependent, chemotherapeutics-induced cytotoxicity in cervical cancer cells may be compromised by catecholamines-induced upregulation of the Sirt1 expression through activating the beta2-adrenergic receptor (zeige ADRB2 Antikörper) signaling

  3. Up-regulation of transcription factor DeltaNp63 led to the decline of miR (zeige MLXIP Antikörper)-181a expression, resulting in an overexpression of the antiaging protein Sirt1, in CD4 (zeige CD4 Antikörper)(+) T cells from HCV-infected individuals. Either reconstituting miR (zeige MLXIP Antikörper)-181a or silencing DeltaNp63 or Sirt1 expression in CD4 (zeige CD4 Antikörper)(+) T cells led to accelerated T cell senescence.

  4. data reveals that the pathway 'HULC/USP22 (zeige USP22 Antikörper)/Sirt1/ protective autophagy' attenuates the sensitivity of hepatocellular carcinoma cells to chemotherapeutic agents, suggesting that this pathway may be a novel target for developing sensitizing strategy to hepatocellular carcinoma chemotherapy

  5. SIRT1 plays a key role in the inflammatory response in aseptic loosening through NF-kappaB (zeige NFKB1 Antikörper) deacetylation .

  6. The tumor-associated NADH oxidase (tNOX (zeige ENOX2 Antikörper))-mediated modulation of the NAD+ concentration and SIRT1 are involved in oxaliplatin-induced apoptosis.

  7. Up-regulated SIRT1 expression may serve as a potential biomarker for predicting the progression of cervical squamous intraepithelial lesions to invasive squamous cell carcinoma.

  8. Human T2D kidneys exhibited more RPTC apoptosis and lower expression of hnRNP F (zeige HNRNPF Antikörper), SIRTUIN-1, and FOXO3alpha than nondiabetic kidneys.

  9. 7-amino-4-methylcoumarin did not affect acetyllysine preference in a multiply acetylated substrate. In contrast, AMC significantly enhanced KDAC6 substrate affinity, greatly reduced Sirt1 activity, eliminated the substrate sequence specificity of KDAC4, and had no consistent effect with KDAC8 substrates.

  10. SIRT1 enzymatically potentiates 1,25-dihydroxyvitamin D3 signaling via VDR (zeige CYP27B1 Antikörper) deacetylation.

Pig (Porcine) Sirtuin 1 (SIRT1) Interaktionspartner

  1. Combining the in vivo and in vitro results, the effect of SIRT1 in granulosa cells apoptosis during follicular atresia was identified.

  2. SIRT1, p53 (zeige TP53 Antikörper) and NF-kappaB (zeige NFKB1 Antikörper) are involved in the control of both the proliferation and the apoptosis of ovarian cells.

  3. the expression of SIRT1 is associated with the Mt number in oocytes

  4. Resveratrol activated sirtuin 1 (Sirt1) gene expression and increased adipose triglyceride lipase (ATGL (zeige PNPLA2 Antikörper)) gene expression and glycerol release. Furthermore, this study found the opposite Sirt1 regulation pattern for PPARgamma (zeige PPARG Antikörper) to that of ATGL (zeige PNPLA2 Antikörper) in adipocytes.

  5. CDK5 (zeige CDK5 Antikörper)-mediated hyperphosphorylation of SIRT1 facilitates the development of endothelial senescence and atherosclerosis.

  6. SIRT1 and LKB1 (zeige STK11 Antikörper)/AMPK (zeige PRKAA1 Antikörper) are the 2 key sensor systems for regulating endothelial cell survival, proliferation and senescence.

  7. Sirt1 may down-regulate pig preadipocytes proliferation and differentiation through repression of adipocyte genes or FoxO1 (zeige FOXO1 Antikörper).

  8. The full-length complementary DNA sequence of porcine Sirt1 was 4,024 bp (GenBank accession no: EU030283), with a 2,226-bp open reading frame encoding a 742-AA protein

  9. Downregulation of miR (zeige MYLIP Antikörper)-199a derepresses hypoxia-inducible factor-1alpha and Sirtuin 1 and recapitulates hypoxia preconditioning in cardiac myocytes.

  10. Sirt1 regulates the expression of FABP3 (zeige FABP3 Antikörper) gene in adipocytes, and PPAR gamma (zeige PPARG Antikörper) apparently plays an important role in this process.

Cow (Bovine) Sirtuin 1 (SIRT1) Interaktionspartner

  1. The results indicate that the variations in the class I sirtuin genes and their corresponding genotypes may be considered as molecular markers for economic traits in cattle breeding.

  2. These results suggest that the SIRT1 gene could be used in marker assisted selection to improve the production traits of Qinchuan cattle.

  3. Downregulation of SIRT1 and FoxO1 (zeige FOXO1 Antikörper) were observed in the backfat tissue of Lilu cattle with increasing age. SIRT1 may play an important role in the development of bovine adipose tissue.

  4. Study indicates that a variation in the SIRT1 gene, the c.-274G variant in the promoter region, is associated with greater body size in Nanyang cattle.

  5. 5 novel SNPs were found in SIRT1. SNP g.-274C>G was shown to have association with 24-months-old body weight and g.17379A>G polymorphism was significantly related to 6 and 12-months-old body weight in NY population; results provide evidence that polymorphisms in SIRT1 are associated with growth efficiency traits

  6. The expression profile of sirtuin 1 and sirtuin 3 (zeige SIRT3 Antikörper) in the liver, muscle, and adipose tissue of calves and bulls is reported.

SIRT1 Antigen-Profil

Beschreibung des Gens

This gene encodes a member of the sirtuin family of proteins, homologs to the yeast Sir2 protein. Members of the sirtuin family are characterized by a sirtuin core domain and grouped into four classes. The functions of human sirtuins have not yet been determined\; however, yeast sirtuin proteins are known to regulate epigenetic gene silencing and suppress recombination of rDNA. Studies suggest that the human sirtuins may function as intracellular regulatory proteins with mono-ADP-ribosyltransferase activity. The protein encoded by this gene is included in class I of the sirtuin family. Alternative splicing results in multiple transcript variants.

Alternative names and synonyms associated with SIRT1

  • sirtuin 1 (SIRT1) Antikörper
  • sirtuin 1 (SRT1) Antikörper
  • sirtuin 1 (LOC100349271) Antikörper
  • sirtuin 1 (Sirt1) Antikörper
  • sirtuin 1 (sirt1) Antikörper
  • AA673258 Antikörper
  • SIR2 Antikörper
  • Sir2a Antikörper
  • Sir2alpha Antikörper
  • sir2l1 Antikörper
  • sirtuin Antikörper
  • sirtuin 1 Antikörper

Bezeichner auf Proteinebene für anti-Sirtuin 1 (SIRT1) Antikörper

sirtuin 1 , NAD-dependent deacetylase sirtuin-1 , NAD-dependent protein deacetylase sirtuin-1 , SIR2-like protein 1 , mSIR2a , regulatory protein SIR2 homolog 1 , sir2-like 1 , sirtuin 1 ((silent mating type information regulation 2, homolog) 1 , SIR2alpha , hSIR2 , hSIRT1 , sirtuin type 1 , sirtuin (silent mating type information regulation 2 homolog) 1 , NAD-dependent deacetylase sirtuin 1 , sirtuin1 , Sir2alpha

100072571 Equus caballus
835670 Arabidopsis thaliana
100349271 Oryctolagus cuniculus
100540948 Meleagris gallopavo
100605499 Nomascus leucogenys
93759 Mus musculus
23411 Homo sapiens
100036963 Xenopus laevis
423646 Gallus gallus
489012 Canis lupus familiaris
751859 Sus scrofa
309757 Rattus norvegicus
101087610 Felis catus
613629 Bos taurus
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