anti-MKNK1 (MKNK1) Antikörper

anti-MAP Kinase Interacting serine/threonine Kinase 1 Antikörper (MKNK1)
Auf finden Sie aktuell 135 MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Antikörper von 17 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen MKNK1 Proteine (11) und MKNK1 Kits (6) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 165 MKNK1 Produkte verfügbar.
2410048M24Rik, Erk-1, Erk1, Ert2, Esrk1, MAPK1, MKNK1, Mnk1, Mtap2k, p44, p44erk1, p44mapk, Prkm3, zgc:171912

Meistgesuchte Reaktivitäten zu anti-MKNK1 (MKNK1) Antikörper

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anti-Human MKNK1 Antikörper:

anti-Mouse (Murine) MKNK1 Antikörper:

anti-Rat (Rattus) MKNK1 Antikörper:

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Am meisten referenzierte anti-MKNK1 Antikörper

  1. Human Polyclonal MKNK1 Primary Antibody für EIA, WB - ABIN359308 : Orton, Ling, Waskiewicz, Cooper, Merrick, Korneeva, Rhoads, Sonenberg, Traugh: Phosphorylation of Mnk1 by caspase-activated Pak2/gamma-PAK inhibits phosphorylation and interaction of eIF4G with Mnk. in The Journal of biological chemistry 2004 (PubMed)

Weitere Antikörper gegen MKNK1 Interaktionspartner

Human MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Interaktionspartner

  1. MNK1 encodes a Ser/Thr protein kinase that interacts with extracellular signal-regulated kinase 1 (zeige MAPK3 Antikörper) and p38 mitogen-activated protein kinase (zeige MAPK14 Antikörper), a pathway that is involved in Blood Pressure regulation through norepinephrine and angiotensin II.

  2. Data show that galeterone (gal (zeige GAL Antikörper)) and VNPT55 inhibit migration and invasion of prostate cancer cells, possibly by down-regulating protein expression via antagonizing the Mnk1/2-eIF4E (zeige EIF4E Antikörper) axis.

  3. data suggest a physiological role for MNK1a-Ser (zeige SIGLEC1 Antikörper)(353) phosphorylation in regulation of the MNK1a kinase, which correlates with increased eIF4E (zeige EIF4E Antikörper) phosphorylation in vitro and in vivo.

  4. Data suggest MNK1/MNK2 (zeige MKNK2 Antikörper) stimulate mRNA translation but only of mRNA containing both 5-prime-terminal cap and hairpin duplex; this stimulation involves up-regulation of phosphorylation/mRNA un-winding activity of eIF4E (zeige EIF4E Antikörper) (via decreased binding to eIF4G (zeige EIF4G1 Antikörper)).

  5. Simultaneous targeting of androgen receptor (zeige AR Antikörper) and MNK1 by novel retinamides inhibits growth of human prostate cancer cell lines.

  6. MNK1 and MNK2 (zeige MKNK2 Antikörper) inhibition ablates eIF4E1 (zeige EIF4E Antikörper) phosphorylation and concurrently enhances eIF4E3 (zeige EIF4E3 Antikörper) expression in diffuse large B-cell lymphoma.

  7. Data show that interferon-gamma (zeige IFNG Antikörper) regulated the metabolism and mRNA translation of macrophages by targeting the kinases mTORC1 and MNK1/2, both of which converge on the selective regulator of translation initiation eukaryotic initiation factor-4E (eIF4E (zeige EIF4E Antikörper)).

  8. Data suggest that a combined pharmacologic inhibition of mTORC1 and Mnk1/2 kinases offers a therapeutic opportunity in blast crisis-chronic myeloid leukemia (BC-CML).

  9. Authors show that MNK (zeige ATP7A Antikörper) regulates SRPK (zeige SRPK1 Antikörper) via mTOR (zeige FRAP1 Antikörper) and AKT (zeige AKT1 Antikörper).

  10. ERK1/2 (zeige MAPK1/3 Antikörper) signal induced MNK (zeige ATP7A Antikörper) catalytic activity enabled enterovirus type 1 internal ribosomal entry site-mediated translation/host cell cytotoxicity through negative regulation of the Ser (zeige SIGLEC1 Antikörper)/Arg (SR)-rich protein kinase (zeige CDK7 Antikörper) (SRPK (zeige SRPK1 Antikörper)).

Mouse (Murine) MAP Kinase Interacting serine/threonine Kinase 1 (MKNK1) Interaktionspartner

  1. Studies indicate that progesterone receptor (zeige PGR Antikörper) transgenic (Pgrcre/+) mitogen inducible gene 6 (Mig (zeige CXCL9 Antikörper)-6over) phosphatase and tensin homolog (zeige PTEN Antikörper) protein (Ptenf/f) knockout mice exhibited an increase of phospho-ERK1/2 (zeige MAPK1/3 Antikörper) and its target genes.

  2. Gpr182 reduction led to increased activation of ERK1/2 in basal and challenge models, demonstrating a potential role for this orphan GPCR in regulating the proliferative capacity of the intestine.

  3. ERK1 (zeige MAPK3 Antikörper) underexpression is associated with obesity.

  4. retinoschisin (zeige RS1 Antikörper) is a novel regulator of MAP kinase (zeige MAPK1 Antikörper) signalling and exerts an anti-apoptotic effect on retinal cells.

  5. Postnatal chondrocyte-specific deletion of Hdac3 (zeige HDAC3 Antikörper) with an inducible Col2a1 (zeige COL2A1 Antikörper)-Cre caused premature production of pErk1/2 and Mmp13 (zeige MMP13 Antikörper) in the growth plate.

  6. The progress of neurogenesis depended on sustained ERK (zeige EPHB2 Antikörper) phosphorylation and resulted in ERK1/2 (zeige MAPK1/3 Antikörper) translocation to the nucleus.

  7. Mirtazapine suppressed 5-HT (zeige DDC Antikörper)-mediated TGF-beta1 (zeige TGFB1 Antikörper)/Smad3 (zeige SMAD3 Antikörper) and ERK1/2 (zeige MAPK1/3 Antikörper) signaling pathways as well as oxidative stress that contribute to the progression of liver fibrosis.

  8. The kinase TPL2 (zeige MAP3K8 Antikörper) activates ERK (zeige EPHB2 Antikörper) and p38 (zeige CRK Antikörper) signaling to promote neutrophilic inflammation

  9. MNK1 participates in mediating high-fat diet-induced insulin (zeige INS Antikörper) resistance. Our findings reveal distinct roles for the MNKs in a novel area of disease biology

  10. HAS2 (zeige HAS2 Antikörper)-produced hyaluronan is required for CD44V6 and TGFbetaRI co-localization and subsequent CD44V6/ERK1 (zeige MAPK3 Antikörper)/EGR1 (zeige EGR1 Antikörper) signaling. These results demonstrate a novel positive-feedback loop that links the myofibroblast phenotype to TGFbeta1 (zeige TGFB1 Antikörper)-stimulated CD44V6/ERK (zeige EPHB2 Antikörper)/EGR1 (zeige EGR1 Antikörper) signaling.

MKNK1 Antigen-Profil

Beschreibung des Gens

This gene encodes a Ser/Thr protein kinase that interacts with, and is activated by ERK1 and p38 mitogen-activated protein kinases, and thus may play a role in the response to environmental stress and cytokines. This kinase may also regulate transcription by phosphorylating eIF4E via interaction with the C-terminal region of eIF4G. Alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with MKNK1

  • MAP kinase interacting serine/threonine kinase 1 (MKNK1) Antikörper
  • MAP kinase interacting serine/threonine kinase 1 (mknk1) Antikörper
  • MAP kinase-interacting serine/threonine kinase 1 (Mknk1) Antikörper
  • mitogen activated protein kinase 3 (Mapk3) Antikörper
  • mitogen-activated protein kinase 3 (Mapk3) Antikörper
  • 2410048M24Rik Antikörper
  • Erk-1 Antikörper
  • Erk1 Antikörper
  • Ert2 Antikörper
  • Esrk1 Antikörper
  • MAPK1 Antikörper
  • MKNK1 Antikörper
  • Mnk1 Antikörper
  • Mtap2k Antikörper
  • p44 Antikörper
  • p44erk1 Antikörper
  • p44mapk Antikörper
  • Prkm3 Antikörper
  • zgc:171912 Antikörper

Bezeichner auf Proteinebene für MKNK1

MAP kinase interacting serine/threonine kinase 1 , MAP kinase-interacting serine/threonine-protein kinase 1 , MAP kinase signal-integrating kinase 1 , MAPK signal-integrating kinase 1 , mnk1 , MAP kinase 1 , MAP kinase 3 , MAP kinase isoform p44 , MAPK 1 , MAPK 3 , extracellular signal-regulated kinase 1 , insulin-stimulated MAP2 kinase , microtubule-associated protein 2 kinase , mitogen-activated 3 , mitogen-activated protein kinase 1 , mitogen-activated protein kinase 3 , p44 MAP kinase , pp42/MAP kinase

469189 Pan troglodytes
555974 Danio rerio
771961 Gallus gallus
8569 Homo sapiens
525647 Bos taurus
17346 Mus musculus
500526 Rattus norvegicus
50689 Rattus norvegicus
26417 Mus musculus
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