anti-SPAG5 (SPAG5) Antikörper

Auf www.antikoerper-online.de finden Sie aktuell 35 Sperm Associated Antigen 5 (SPAG5) Antikörper von 13 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SPAG5 Kits (4) und SPAG5 Proteine (4) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 47 SPAG5 Produkte verfügbar.
Synonyme:
AI874642, D11Bhm180e, Deepest, hMAP126, MAP126, Mastrin, S17, SPAG5
Alle Antikörper anzeigen Gen GeneID UniProt
SPAG5 10615 Q96R06
SPAG5 54141 Q7TME2
SPAG5 252918  

Meistgesuchte Reaktivitäten zu anti-SPAG5 (SPAG5) Antikörper

anti-Human SPAG5 Antikörper:

anti-Mouse (Murine) SPAG5 Antikörper:

anti-Rat (Rattus) SPAG5 Antikörper:

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Weitere Antikörper gegen SPAG5 Interaktionspartner

Human Sperm Associated Antigen 5 (SPAG5) Interaktionspartner

  1. Low SPAG5 expression is associated with low chemotherapy sensitivity in breast cancer.

  2. findings reveal a direct physical link between two important regulators of mitotic progression and demonstrate the critical role of the NuMA (zeige NUMA1 Antikörper)-Astrin interaction for accurate cell division.

  3. Mechanistically, Plk1 (zeige PLK1 Antikörper) acts as an upstream kinase for Astrin phosphorylation by Cdk1 (zeige CDK1 Antikörper) and targeting phospho-Astrin to KTs, leading to the recruitment of outer KT components, such as Cenp-E (zeige CENPE Antikörper), and the stable attachment of spindles to KTs.

  4. Results showed a progression-driving role of SPAG5 in prostate cancer which can be regulated by miR (zeige MLXIP Antikörper)-539.

  5. Molecular requirements for the inter-subunit interaction and kinetochore recruitment of SKAP (zeige KNSTRN Antikörper) and Astrin have been reported.

  6. SPAG5 upregulation relates to poor prognosis in cervical cancer patients, and SPAG5 is a regulator of mTOR (zeige FRAP1 Antikörper) activity during taxol treatment in cervical cancer.

  7. Astrin acts as a mitotic phosphoprotein during the regulation of mitosis.

  8. Study identifies astrin as an essential negative mTORC1 regulator in the cellular stress response. Upon stress, astrin inhibits mTORC1 association and recruits the mTORC1 component raptor (zeige RPTOR Antikörper) to stress granules, thereby preventing mTORC1-hyperactivation-induced apoptosis.

  9. Data show that CLASP1 (zeige CLASP1 Antikörper)-astrin-Kif2b (zeige KIF2B Antikörper) complex acts as a central switch at kinetochores that defines mitotic progression and promotes fidelity by temporally regulating kinetochore-microtuble attachments.

  10. These findings suggest that the silencing of astrin induce a p53 (zeige TP53 Antikörper)-dependent apoptosis and has an additive effect on paclitaxel treatment.

Mouse (Murine) Sperm Associated Antigen 5 (SPAG5) Interaktionspartner

  1. cloning and genomic structure of mastrin; mastrin protein was demonstrated to localize to mitotic spindles during mitosis[masatrin]

  2. Loss-of-function of Astrin by RNAi and overexpression of the coiled-coil domain results in spindle disorganization, chromosome misalignment and meiosis progression arrest.

SPAG5 Antigen-Profil

Beschreibung des Gens

This gene encodes a protein associated with the mitotic spindle apparatus. The encoded protein may be involved in the functional and dynamic regulation of mitotic spindles.

Alternative names and synonyms associated with SPAG5

  • sperm associated antigen 5 (SPAG5) Antikörper
  • sperm associated antigen 5 (Spag5) Antikörper
  • AI874642 Antikörper
  • D11Bhm180e Antikörper
  • Deepest Antikörper
  • hMAP126 Antikörper
  • MAP126 Antikörper
  • Mastrin Antikörper
  • S17 Antikörper
  • SPAG5 Antikörper

Bezeichner auf Proteinebene für SPAG5

sperm associated antigen 5 , sperm-associated antigen 5-like , astrin , mitotic spindle associated protein p126 , mitotic spindle coiled-coil related protein , mitotic spindle-associated protein p126 , sperm-associated antigen 5 , microtubule-associated protein

GENE ID SPEZIES
709400 Macaca mulatta
739263 Pan troglodytes
100059272 Equus caballus
100286810 Sus scrofa
100466628 Ailuropoda melanoleuca
100602580 Nomascus leucogenys
10615 Homo sapiens
54141 Mus musculus
252918 Rattus norvegicus
480623 Canis lupus familiaris
504585 Bos taurus
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