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EDG-6

S1PR4 WB, PC Whole Cell Lysate
Produktnummer ABIN924992
600,00 €
Zzgl. Versandkosten 20,00 € und MwSt
100 μL
Lieferung nach: Deutschland
Lieferung in 15 bis 22 Werktagen

Kurzübersicht für EDG-6 (ABIN924992)

Target

S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

Applikation

Western Blotting (WB), Positive Control (PC)

Lysate Fraction

Whole Cell Lysate
  • Applikationshinweise

    For use as a positive control with EDG-6 polyclonal antibody ABIN187788 for Western blot analysis. Use 10-20 µl of EDG-6 cell lysate per lane as a control when using EDG-6 antibody.

    Beschränkungen

    Nur für Forschungszwecke einsetzbar
  • Format

    Liquid

    Buffer

    Provided in 10% glycerol, 063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue and 5% 2-mercaptoethanol.

    Lagerung

    -20 °C
  • Target

    S1PR4 (Sphingosine-1-Phosphate Receptor 4 (S1PR4))

    Andere Bezeichnung

    EDG-6

    Hintergrund

    EDG-6 Trnasfected Cell Positive Control Lysate. EDG-6 belongs to a family of G-protein coupled receptors whose ligands are lysophospholipids. The ligand for EDG-6 is a sphingosine-1- phosphate. There are 8 known members of the EDG receptor family and they are implicated in mediating growth related effects such as induction of cellular proliferation, alterations in differentiation and survival and suppression of apoptosis. They also evoke cellular effector functions that are dependent on cytoskeletal responses such as contraction, secretion, adhesion, and chemotaxis. EDG receptors are developmentally regulated and differ in tissue distribution. They couple to multiple types of G proteins to signal through ras and MAP kinase, rho, phospholipase C, and several protein tyrosine kinases. EDG-6 is expressed in lymphoid and hematopoietic tissue and in the lungs.
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