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IL2RG Proteine (IL2RG)

Interleukin 2 Receptor, gamma Proteine (IL2RG)
Auf finden Sie aktuell 26 Interleukin 2 Receptor, gamma (IL2RG) Proteine von 10 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen IL2RG Antikörper (146) und IL2RG Kits (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 202 IL2RG Produkte verfügbar.
Ab2-183, CD132, CIDX, gamma(c), gc, IL-2RG, IMD4, P64, SCIDX, SCIDX1, [g]c
alle Proteine anzeigen Gen GeneID UniProt
IL2RG 140924  
IL2RG 3561 P31785
IL2RG 16186 P34902

Weitere Synonyme anzeigen

IL2RG Proteine (IL2RG) nach Spezies

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Am meisten referenzierte IL2RG Proteine

  1. Human IL2RG Protein expressed in HEK-293 Cells - ABIN2181389 : Kondo, Takeshita, Ishii, Nakamura, Watanabe, Arai, Sugamura: Sharing of the interleukin-2 (IL-2) receptor gamma chain between receptors for IL-2 and IL-4. in Science (New York, N.Y.) 1994 (PubMed)
    Zeige alle 3 Referenzen für ABIN2181389

Weitere Proteine zu IL2RG Interaktionspartnern

Rhesus Monkey Interleukin 2 Receptor, gamma (IL2RG) Interaktionspartner

  1. Down-regulation of gamma(c) during early HIV/SIV infection may inhibit T-cell function, particularly of CD8 (zeige CD8A Proteine)(+) T cells, and, may be linked with immune failure and loss of viral containment.

Human Interleukin 2 Receptor, gamma (IL2RG) Interaktionspartner

  1. A deletion mutation in IL2RG gene results in X-linked severe combined immunodeficiency (zeige PRKDC Proteine) with an atypical phenotype

  2. novel missense mutation in Japanese patient results in atypical X-linked severe combined immunodeficiency (zeige PRKDC Proteine) with the presence of T cells and NK cells and revertant somatic mosaicism

  3. reversion of mutation in common lymphoid progenitor results in mild phenotype of SCID (zeige PRKDC Proteine)

  4. High IL2RG expression is associated with Sezary syndrome.

  5. Identification of a gammaC splice isoform revealed expression of soluble gammaC proteins (sgammaC). sgammaC directly interacted with surface IL-2Rbeta (zeige IL2RB Proteine) to suppress IL-2 (zeige IL2 Proteine) signaling and to promote pro-inflammatory Th17 cell differentiation. [review]

  6. Study show the detection of IL2RG mutations in 2 families with X-SCID (zeige PRKDC Proteine) and identified 2 novel mutations, confirming the X-SCID (zeige PRKDC Proteine) pedigrees.

  7. Interleukin 2 receptor subunit gamma mutation is associated with X-linked severe combined immunodeficiency (zeige PRKDC Proteine).

  8. Results demonstrate that IL2Rgamma has an onogenic role in JAK3 (zeige JAK3 Proteine)-mutation-positive leukemias.

  9. findings suggest that over-expression of the IL2RG gene may be implicated in altered immune response in schizophrenia and contribute to the pathomechanisms of this disorder

  10. this is the first report on a de novo mutation in the IL2RG gene in a patient born after IVF (zeige SCN5A Proteine)

Mouse (Murine) Interleukin 2 Receptor, gamma (IL2RG) Interaktionspartner

  1. We have confirmed the activation of human peripheral blood lymphocytes after being xenografted in immunodeficient Rag2 (zeige RAG2 Proteine)-/-IL2Rgnull mice.

  2. Results demonstrate that IL2Rgamma has an onogenic role in JAK3 (zeige JAK3 Proteine)-mutation-positive leukemias.

  3. findings demonstrate that NOD SCID (zeige PRKDC Proteine) IL2R (zeige IL2RA Proteine) common gamma chain -/- mice are capable of engraftment of canine PBLs yet develop graft versus host disease similar to Hu-PBL-SCID (zeige PRKDC Proteine) mice

  4. Interleukin-2 (zeige IL2 Proteine) signalling is modulated by a labile disulfide bond in the CD132 chain of its receptor.

  5. gammac expression was required to signal the differentiation of MHC class I-specific thymocytes into CD8 (zeige CD8A Proteine)+ cytotoxic lineage T cells and into invariant natural killer T cells.

  6. analysis of multiorgan metastasis of human HER-2 (zeige ERBB2 Proteine)+ breast cancer in Rag2 (zeige RAG2 Proteine)-/-;Il2rg-/- mice and treatment with PI3K inhibitor

  7. Results indicated that the extracellular and transmembrane domains of gammaC and IL-13Ralpha1 controlled the magnitude of the intracellular signaling response to IL-4 (zeige IL4 Proteine) and IL-13 (zeige IL13 Proteine).

  8. physiologic impact of CB hematopoietic progenitor cell hypofucosylation was investigated in vivo in NOD-SCID interleukin (IL)-2Rgamma(null) (NSG) mice

  9. CD34 (zeige CD34 Proteine)+ CD133+ hematopoietic stem cells cultured with growth factors including Angptl5 efficiently engraft adult NOD-SCID (zeige PRKDC Proteine) Il2rgamma-/- (NSG) mice

  10. IL-2 (zeige IL2 Proteine) receptor complex has an essential protective role in immunity to blood-stage malaria. Protection is achieved by gammac cytokine family members signalling through the IL-2Rgammac.

IL2RG Protein Überblick

Protein Überblick

The protein encoded by this gene is an important signaling component of many interleukin receptors, including those of interleukin -2, -4, -7 and -21, and is thus referred to as the common gamma chain. Mutations in this gene cause X-linked severe combined immunodeficiency (XSCID), as well as X-linked combined immunodeficiency (XCID), a less severe immunodeficiency disorder.

Alternative names and synonyms associated with IL2RG

  • interleukin 2 receptor, gamma (IL2RG)
  • interleukin 2 receptor, gamma (il2rg)
  • interleukin 2 receptor, gamma (Il2rg)
  • interleukin 2 receptor, gamma chain (Il2rg)
  • Ab2-183 Protein
  • CD132 Protein
  • CIDX Protein
  • gamma(c) Protein
  • gc Protein
  • IL-2RG Protein
  • IMD4 Protein
  • P64 Protein
  • SCIDX Protein
  • SCIDX1 Protein
  • [g]c Protein

Bezeichner auf Proteinebene für IL2RG

cytokine receptor common subunit gamma , interleukin 2 receptor gamma , interleukin 2 receptor, gamma (severe combined immunodeficiency) , membrane receptor Il2rg , interleukin 2 receptor, gamma , CD132 antigen , IL-2 receptor subunit gamma , IL-2R subunit gamma , common cytokine receptor gamma chain , gammaC , IL-2R gamma chain , IL-2RG , cytokine receptor common gamma chain , gamma-C , interleukin-2 receptor gamma chain , interleukin-2 receptor subunit gamma , p64 , interleukin 2 receptor gamma chain , common gamma chain , gamma C receptor

397156 Sus scrofa
641338 Macaca mulatta
100036958 Xenopus laevis
100585758 Nomascus leucogenys
140924 Rattus norvegicus
3561 Homo sapiens
281862 Bos taurus
403851 Canis lupus familiaris
16186 Mus musculus
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