anti-SMAD7 (SMAD7) Antikörper

Bezeichnung:
anti-SMAD, Mothers Against DPP Homolog 7 Antikörper (SMAD7)
Auf www.antikoerper-online.de finden Sie aktuell 90 SMAD, Mothers Against DPP Homolog 7 (SMAD7) Antikörper von 23 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen SMAD7 Kits (45) und SMAD7 Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 146 SMAD7 Produkte verfügbar.
Synonyme:
CRCS3, madh7, MADH8, Smad7a, Smad10, xsmad7

Meistgesuchte Reaktivitäten zu anti-SMAD7 (SMAD7) Antikörper

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anti-Human SMAD7 Antikörper:

anti-Mouse (Murine) SMAD7 Antikörper:

anti-Rat (Rattus) SMAD7 Antikörper:

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Am meisten referenzierte anti-SMAD7 Antikörper

  1. Human Polyclonal SMAD7 Primary Antibody für IHC, IHC (p) - ABIN4354717 : Roman-Blas, Stokes, Jimenez: Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. in Osteoarthritis and cartilage 2007 (PubMed)
    Zeige alle 9 Referenzen für 4354717

  2. Human Polyclonal SMAD7 Primary Antibody für WB - ABIN4354712 : Kleiter, Pedré, Mueller, Poeschl, Couillard-Despres, Spruss, Bogdahn, Giegerich, Steinbrecher: Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis. in Journal of neuroimmunology 2007 (PubMed)
    Zeige alle 4 Referenzen für 4354712

  3. Human Polyclonal SMAD7 Primary Antibody für IHC (p), WB - ABIN3044025 : Tao, Hu, Li, Liu, Wu, Li, Fu, Wei, Luo: Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor ?/Smad pathways. in Transplantation proceedings 2011 (PubMed)
    Zeige alle 3 Referenzen für 3044025

  4. Human Monoclonal SMAD7 Primary Antibody für IHC (p), ELISA - ABIN517666 : Chen, Yang, Huang, Hsue, Lin et al.: Aberrant expression in multiple components of the transforming growth factor-?1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell ... in Oral oncology 2011 (PubMed)
    Zeige alle 2 Referenzen für 517666

  5. Cow (Bovine) Polyclonal SMAD7 Primary Antibody für WB - ABIN2779417 : Komuro, Imamura, Saitoh, Yoshida, Yamori, Miyazono, Miyazawa: Negative regulation of transforming growth factor-beta (TGF-beta) signaling by WW domain-containing protein 1 (WWP1). in Oncogene 2004 (PubMed)

Weitere Antikörper gegen SMAD7 Interaktionspartner

Human SMAD, Mothers Against DPP Homolog 7 (SMAD7) Interaktionspartner

  1. ASPP2 (zeige TP53BP2 Antikörper) suppresses invasion, peritoneal dissemination and TGF-beta1 (zeige TGFB1 Antikörper)-induced EMT (zeige ITK Antikörper) by inhibiting Smad7 degradation mediated by ITCH in gastric cancer cells.

  2. Transforming Growth Factor beta inhibitor peptide P144 (zeige TCERG1 Antikörper) downregulates SKI (zeige SKI Antikörper) and an upregulates SMAD7 at both transcriptional and translational levels in glioblastoma cell lines.

  3. The inverse correlation between Smad7 and AhR (zeige AHR Antikörper) expression helps to propagate inflammatory signals in the gut (zeige GUSB Antikörper) in Crohn's disease.

  4. RNF11 (zeige RNF11 Antikörper) sequestration of the E3 ligase SMURF2 (zeige SMURF2 Antikörper) on membranes antagonizes SMAD7 down-regulation of transforming growth factor beta signaling

  5. NR2F2 (zeige NR2F1 Antikörper) could promote TGF-beta (zeige TGFB1 Antikörper)-induced epithelial-mesenchymal transition of colorectal carcinoma cells and inhibit Smad7 expression via transactivation of miR (zeige MLXIP Antikörper)-21.

  6. this study shows that in refractory celiac disease, high Smad7 associates with defective TGF-beta1 (zeige TGFB1 Antikörper) signaling and sustains inflammatory cytokine production

  7. miR (zeige MLXIP Antikörper)-590-5p promotes osteoblast differentiation by indirectly protecting and stabilizing the Runx2 (zeige RUNX2 Antikörper) protein by targeting Smad7 gene expression.

  8. the findings show that TIEG1 (zeige KLF10 Antikörper) is highly expressed in human keloids and that it directly binds and represses Smad7 promoter-mediated activation of TGF-beta (zeige TGFB1 Antikörper)/Smad2 (zeige SMAD2 Antikörper) signaling

  9. A significant association was found between the low expression of inhibitory protein SMAD-7 and both zeta-chain-associated protein kinase (zeige CDK7 Antikörper) 70-negative cells (p = 0.04) and lower apoptotic index (p = 0.004). No differences were observed in SMAD-2 (zeige SMAD2 Antikörper)/3 expression. In conclusion, our results demonstrate a significant correlation between greater SMAD-1 (zeige GARS Antikörper)/8 and lower SMAD-4 (zeige SMAD4 Antikörper) expression in chronic lymphocytic leukemia cells

  10. miRNA-181a appears to play a potential role in pancreatic beta-cells dysfunction via SMAD7.

Mouse (Murine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) Interaktionspartner

  1. study reports an alternately-spliced form of Smad7, Smad7Delta, that is induced by TGF-beta (zeige TGFB1 Antikörper) and CLIC4 (zeige CLIC4 Antikörper), is a dominant inhibitor of Smad7 and enhances TGF-beta (zeige TGFB1 Antikörper) signaling

  2. Pancreatic depletion of SMAD7 resulted in age-dependent increases in beta cell dysfunction with accelerated glucose intolerance, followed by overt diabetes.

  3. The inverse correlation between Smad7 and AhR (zeige AHR Antikörper) expression helps to propagate inflammatory signals in the gut (zeige GUSB Antikörper) in Crohn's disease.

  4. results indicate that miR (zeige MLXIP Antikörper)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) and Wnt (zeige WNT2 Antikörper) signaling pathway by directly targeting Smad7 and Tcf7l2 (zeige TCF7L2 Antikörper)

  5. microRNA-497 modulates breast cancer cell proliferation, invasion, and survival by targeting SMAD7.

  6. results indicate that miR (zeige MLXIP Antikörper)-195a-5p inhibits MTEC1 proliferation, at least in part, via down-regulation of Smad7

  7. Data indicate that, in irritable bowel disease, high Smad7 contributes to sustain detrimental immune responses and knockdown of this molecule can help attenuate the ongoing mucosal inflammation in patients with such disorders

  8. Hic-5 (zeige TGFB1I1 Antikörper) deficiency attenuates the activation of hepatic stellate cells and liver fibrosis though reducing the TGF-beta (zeige TGFB1 Antikörper)/Smad2 (zeige SMAD2 Antikörper) signaling by upregulation of Smad7

  9. Data show that microRNA miR (zeige MLXIP Antikörper)-21 was significantly upregulated by bone morphogenetic protein 9 (BMP9 (zeige GDF2 Antikörper)) during the osteogenesis the multilineage cells (MMCs) by suppressing Smad7 protein.

  10. Genetic disruption of Smad7 impairs skeletal muscle growth and regeneration

Xenopus laevis SMAD, Mothers Against DPP Homolog 7 (SMAD7) Interaktionspartner

  1. Tril (zeige TRIL Antikörper) is a novel component of a Bmp-Gata2 (zeige GATA2 Antikörper) positive-feedback loop that plays an essential role in hematopoietic specification, by targeting Smad7 for degradation.

  2. cTid1 can bind to other members of the Smad (zeige SMAD1 Antikörper) family and that highest binding activity occurs with the negative regulatory Smad7, through the conserved MH2 (zeige SCN4A Antikörper) domain

  3. Smad7 has a role in Xenopus mesodermal and neural induction

Pig (Porcine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) Interaktionspartner

  1. SMAD7 plays a potentially important role in mammalian prenatal skeletal muscle development and is a candidate gene for promoting greater weaning weight in pig breeding.

  2. MiR (zeige MYLIP Antikörper)-92a inhibits porcine ovarian granulosa cell apoptosis by targeting Smad7 gene

Cow (Bovine) SMAD, Mothers Against DPP Homolog 7 (SMAD7) Interaktionspartner

  1. a detailed computational model for TGF-beta (zeige TGFB1 Antikörper) signalling that incorporates elements of previous models together with crosstalking between Smad1 (zeige SMAD1 Antikörper)/5/8 and Smad2 (zeige SMAD2 Antikörper)/3 channels through a negative feedback loop dependent on Smad7.

  2. Results suggest that myostatin (zeige MSTN Antikörper) auto-regulates its gene expression through a Smad7 dependent mechanism in myogenic cells.

SMAD7 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.

Alternative names and synonyms associated with SMAD7

  • SMAD family member 7 (SMAD7) Antikörper
  • SMAD family member 7 (Smad7) Antikörper
  • SMAD family member 7 (smad7) Antikörper
  • CRCS3 Antikörper
  • madh7 Antikörper
  • MADH8 Antikörper
  • Smad7a Antikörper
  • Smad10 Antikörper
  • xsmad7 Antikörper

Bezeichner auf Proteinebene für SMAD7

MAD (mothers against decapentaplegic, Drosophila) homolog 7 , MAD homolog 8 , Mothers against decapentaplegic, drosophila, homolog of, 7 , SMAD, mothers against DPP homolog 7 , hSMAD7 , mothers against DPP homolog 8 , mothers against decapentaplegic homolog 7 , MAD homolog 7 , SMAD 7 , madh8 , mothers against DPP homolog 7 , mothers against decapentaplegic homolog 8 , MAD, mothers against decapentaplegic homolog 7 , mothers against DPP 7 , mothers against decapentaplegic-like protein 7 , SMAD family member 7

GENE ID SPEZIES
4092 Homo sapiens
17131 Mus musculus
81516 Rattus norvegicus
490570 Canis lupus familiaris
394331 Xenopus laevis
455411 Pan troglodytes
100717293 Cavia porcellus
100521305 Sus scrofa
535916 Bos taurus
429683 Gallus gallus
443160 Ovis aries
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