Use your antibodies-online credentials, if available.
Keine Produkte auf Ihrer Vergleichsliste.
Ihr Warenkorb ist leer.
Alle Spezies anzeigen
Weitere Synonyme anzeigen
Wählen Sie die Spezies und Applikation aus
anti-Human SMAD7 Antikörper:
anti-Mouse (Murine) SMAD7 Antikörper:
anti-Rat (Rattus) SMAD7 Antikörper:
Sie gelangen zu unserer vorgefilterten Suche.
Human Polyclonal SMAD7 Primary Antibody für IHC, IHC (p) - ABIN4354717
Roman-Blas, Stokes, Jimenez: Modulation of TGF-beta signaling by proinflammatory cytokines in articular chondrocytes. in Osteoarthritis and cartilage 2007
Show all 9 Pubmed References
Human Polyclonal SMAD7 Primary Antibody für WB - ABIN4354712
Kleiter, Pedré, Mueller, Poeschl, Couillard-Despres, Spruss, Bogdahn, Giegerich, Steinbrecher: Inhibition of Smad7, a negative regulator of TGF-beta signaling, suppresses autoimmune encephalomyelitis. in Journal of neuroimmunology 2007
Show all 4 Pubmed References
Human Polyclonal SMAD7 Primary Antibody für IHC (p), WB - ABIN3044025
Tao, Hu, Li, Liu, Wu, Li, Fu, Wei, Luo: Tranilast prevents the progression of chronic cyclosporine nephrotoxicity through regulation of transforming growth factor ?/Smad pathways. in Transplantation proceedings 2011
Show all 3 Pubmed References
Human Monoclonal SMAD7 Primary Antibody für IHC (p), ELISA - ABIN517666
Chen, Yang, Huang, Hsue, Lin et al.: Aberrant expression in multiple components of the transforming growth factor-?1-induced Smad signaling pathway during 7,12-dimethylbenz[a]anthracene-induced hamster buccal-pouch squamous-cell ... in Oral oncology 2011
Show all 2 Pubmed References
Cow (Bovine) Polyclonal SMAD7 Primary Antibody für WB - ABIN2779418
Briones-Orta, Sosa-Garrocho, Moreno-Alvarez, Fonseca-Sánchez, Macías-Silva: SnoN co-repressor binds and represses smad7 gene promoter. in Biochemical and biophysical research communications 2006
Furthermore, MERS coronavirus induced apoptosis through upregulation of Smad7 and fibroblast growth factor 2 (FGF2 (zeige FGF2 Antikörper)) expression in both kidney and lung cells.
findings demonstrate TGF-beta (zeige TGFB1 Antikörper) enhances expression of USP26 (zeige USP26 Antikörper) and reinforces SMAD7 stability by limiting the ubiquitin-mediated turnover of SMAD7; clinically, loss of USP26 (zeige USP26 Antikörper) correlates with high TGF-beta (zeige TGFB1 Antikörper) activity and confers poor prognosis in glioblastoma; data identify USP26 (zeige USP26 Antikörper) as a novel negative regulator of the TGF-beta (zeige TGFB1 Antikörper) pathway and suggest that loss of USP26 (zeige USP26 Antikörper) expression may be an important factor in glioblastoma pathogenesis
In conclusion, our study demonstrated that COL1A2 (zeige COL1A2 Antikörper)-AS1 (zeige PTGDR Antikörper)/miR (zeige MLXIP Antikörper)-21/Smad (zeige SMAD1 Antikörper) pathway plays an important role in inhibiting hypertrophic scar formation, and suggested this novel pathway may be a new target for hypertrophic scar treatment.
Our data revealed the SMAD7 loci is associated with hepatocellular carcinoma susceptibility and its clinicopathologic development.
Smad7 expression in necrotizing enterocolitis macrophages interrupts TGF-beta (zeige TGFB1 Antikörper) signaling and promotes NF-kappaB (zeige NFKB1 Antikörper)-mediated inflammatory signaling in these cells through increased expression of IKK-beta (zeige IKBKB Antikörper)
SMAD7 gene and specifically the allele C could be protective for colorectal cancer (CRC (zeige CALR Antikörper)). An independent protective association was also observed between high adherence Mediterranean diet pattern and CRC (zeige CALR Antikörper) risk.
Smad7 inhibition diminishes interaction of PKR (zeige PKLR Antikörper) with protein kinase inhibitor p58 (p58 (zeige DNAJC3 Antikörper)(IPK)).
Smad7 regulates TGF-beta1 (zeige TGFB1 Antikörper) signaling via a negative feedback loop and mediates the interaction between TGF-beta1 (zeige TGFB1 Antikörper) and other signaling pathways; suggesting that Smad7 over expression may have therapeutic potential in ALL.
Missense variant in smad7 gene is associated with colorectal cancer.
ASPP2 (zeige TP53BP2 Antikörper) suppresses invasion, peritoneal dissemination and TGF-beta1 (zeige TGFB1 Antikörper)-induced EMT (zeige ITK Antikörper) by inhibiting Smad7 degradation mediated by ITCH in gastric cancer cells.
a heterozygous deletion of SMAD7 results in an increased proliferation of Muller cell progenitors in the central retina at postnatal day 4, the time window when Muller cells differentiate in the mouse retina; this in turn results in a thickened retina and inner nuclear layer and a higher number of differentiated Muller cells in the more developed retina
changes were associated with increased expression of the antifibrotic protein Smad7 and higher levels of sphingosine in Sphk2 (zeige SPHK2 Antikörper)(-/-) unilateral ureteral obstruction kidneys
Smad7 plays a protective role in acute kidney injury by preventing tubular epithelial cells from the G1 cell cycle arrest.
study reports an alternately-spliced form of Smad7, Smad7Delta, that is induced by TGF-beta (zeige TGFB1 Antikörper) and CLIC4 (zeige CLIC4 Antikörper), is a dominant inhibitor of Smad7 and enhances TGF-beta (zeige TGFB1 Antikörper) signaling
Pancreatic depletion of SMAD7 resulted in age-dependent increases in beta cell dysfunction with accelerated glucose intolerance, followed by overt diabetes.
The inverse correlation between Smad7 and AhR (zeige AHR Antikörper) expression helps to propagate inflammatory signals in the gut (zeige GUSB Antikörper) in Crohn's disease.
results indicate that miR (zeige MLXIP Antikörper)-181a-5p promotes 3T3-L1 preadipocyte differentiation and adipogenesis through regulating TGFbeta (zeige TGFB1 Antikörper)/Smad (zeige SMAD1 Antikörper) and Wnt (zeige WNT2 Antikörper) signaling pathway by directly targeting Smad7 and Tcf7l2 (zeige TCF7L2 Antikörper)
microRNA-497 modulates breast cancer cell proliferation, invasion, and survival by targeting SMAD7.
results indicate that miR (zeige MLXIP Antikörper)-195a-5p inhibits MTEC1 proliferation, at least in part, via down-regulation of Smad7
Data indicate that, in irritable bowel disease, high Smad7 contributes to sustain detrimental immune responses and knockdown of this molecule can help attenuate the ongoing mucosal inflammation in patients with such disorders
Tril (zeige TRIL Antikörper) is a novel component of a Bmp-Gata2 (zeige GATA2 Antikörper) positive-feedback loop that plays an essential role in hematopoietic specification, by targeting Smad7 for degradation.
cTid1 can bind to other members of the Smad (zeige SMAD1 Antikörper) family and that highest binding activity occurs with the negative regulatory Smad7, through the conserved MH2 (zeige SCN4A Antikörper) domain
Smad7 has a role in Xenopus mesodermal and neural induction
SMAD7 plays a potentially important role in mammalian prenatal skeletal muscle development and is a candidate gene for promoting greater weaning weight in pig breeding.
MiR (zeige MYLIP Antikörper)-92a inhibits porcine ovarian granulosa cell apoptosis by targeting Smad7 gene
a detailed computational model for TGF-beta (zeige TGFB1 Antikörper) signalling that incorporates elements of previous models together with crosstalking between Smad1 (zeige SMAD1 Antikörper)/5/8 and Smad2 (zeige SMAD2 Antikörper)/3 channels through a negative feedback loop dependent on Smad7.
Results suggest that myostatin (zeige MSTN Antikörper) auto-regulates its gene expression through a Smad7 dependent mechanism in myogenic cells.
The protein encoded by this gene is a nuclear protein that binds the E3 ubiquitin ligase SMURF2. Upon binding, this complex translocates to the cytoplasm, where it interacts with TGF-beta receptor type-1 (TGFBR1), leading to the degradation of both the encoded protein and TGFBR1. Expression of this gene is induced by TGFBR1. Variations in this gene are a cause of susceptibility to colorectal cancer type 3 (CRCS3). Several transcript variants encoding different isoforms have been found for this gene.
MAD (mothers against decapentaplegic, Drosophila) homolog 7
, MAD homolog 8
, Mothers against decapentaplegic, drosophila, homolog of, 7
, SMAD, mothers against DPP homolog 7
, mothers against DPP homolog 8
, mothers against decapentaplegic homolog 7
, MAD homolog 7
, SMAD 7
, mothers against DPP homolog 7
, mothers against decapentaplegic homolog 8
, MAD, mothers against decapentaplegic homolog 7
, mothers against DPP 7
, mothers against decapentaplegic-like protein 7
, SMAD family member 7