FRS2 Proteine
(Fibroblast Growth Factor Receptor Substrate 2 (FRS2))
Adapter protein that links activated FGR and NGF receptors to downstream signaling pathways. Plays an important role in the activation of MAP kinases and in the phosphorylation of PIK3R1, the regulatory subunit of phosphatidylinositol 3- kinase, in response to ligand-mediated activation of FGFR1. Modulates signaling via SHC1 by competing for a common binding site on NTRK1.
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FRS2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
2 Referenzen
FRS2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
Greater than 95 % by SDS-PAGE gel analyses
WB, ELISA
1 image
FRS2
Spezies: Human
Wirt: Wheat germ
Recombinant
WB, ELISA, AA, AP
1 image
FRS2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
FRS2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
WB, SDS, ELISA
FRS2
Spezies: Human
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, Imm, PC
FRS2
Spezies: Human
Wirt: HEK-293 Cells
Recombinant
> 80 % as determined by SDS-PAGE and Coomassie blue staining
AbP, STD
1 image
FRS2
Spezies: Maus
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
FRS2
Spezies: Ratte
Wirt: Escherichia coli (E. coli)
Recombinant
> 95 %
WB, SDS, ELISA, IP
1 image
Aktuelle Publikationen für unsere FRS2 Proteine
: "STAT1 and STAT3 do not participate in FGF-mediated growth arrest in chondrocytes." in: Journal of cell science, Vol. 121, Issue Pt 3, pp. 272-81, (2008) (PubMed).: "Bisindolylmaleimide I suppresses fibroblast growth factor-mediated activation of Erk MAP kinase in chondrocytes by preventing Shp2 association with the Frs2 and Gab1 adaptor proteins." in: The Journal of biological chemistry, Vol. 282, Issue 5, pp. 2929-36, (2007) (PubMed).
Aliase für FRS2 Proteine
fibroblast growth factor receptor substrate 2 (FRS2) Proteinefibroblast growth factor receptor substrate 2b (frs2b) Proteine
fibroblast growth factor receptor substrate 2 (Frs2) Proteine
4732458E18 Proteine
C330018A15Rik Proteine
frs2 Proteine
FRS2A Proteine
FRS2alpha Proteine
Frs2alpha Proteine
SNT Proteine
SNT-1 Proteine
SNT1 Proteine
wu:fd21h10 Proteine
zgc:91973 Proteine
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