anti-Polymerase (DNA Directed) kappa (POLK) Antikörper

anti-Polymerase (DNA Directed) kappa Antikörper (POLK)
Auf finden Sie aktuell 91 Polymerase (DNA Directed) kappa (POLK) Antikörper von 14 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Polymerase (DNA Directed) kappa Proteine (5) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 105 Polymerase (DNA Directed) kappa Produkte verfügbar.
Dinb1, DINP, DKFZp459J211, LAK-1, POLK, POLQ, Pols, si:ch211-254o18.3, TRF4, TRF4-1

Meistgesuchte Reaktivitäten zu anti-Polymerase (DNA Directed) kappa (POLK) Antikörper

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anti-Mouse (Murine) Antikörper:

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Am meisten referenzierte anti-Polymerase (DNA Directed) kappa Antikörper

  1. Human Polyclonal POLK Primary Antibody für WB - ABIN1881669 : Lone, Townson, Uljon, Johnson, Brahma, Nair, Prakash, Prakash, Aggarwal: Human DNA polymerase kappa encircles DNA: implications for mismatch extension and lesion bypass. in Molecular cell 2007 (PubMed)
    Zeige alle 5 Referenzen für 1881669

  2. Cow (Bovine) Polyclonal POLK Primary Antibody für WB - ABIN2783505 : Hile, Eckert: DNA polymerase kappa produces interrupted mutations and displays polar pausing within mononucleotide microsatellite sequences. in Nucleic acids research 2008 (PubMed)

  3. Human Monoclonal POLK Primary Antibody für IF, IHC (p) - ABIN565606 : Sekimoto, Oda, Kurashima, Hanaoka, Yamashita: Both high-fidelity replicative and low-fidelity Y-family polymerases are involved in DNA rereplication. in Molecular and cellular biology 2015 (PubMed)

Weitere Antikörper gegen Polymerase (DNA Directed) kappa Interaktionspartner

Mouse (Murine) Polymerase (DNA Directed) kappa (POLK) Interaktionspartner

  1. the extreme N-terminal part of Polkappa (zeige POLL Antikörper) is required for the processivity and fidelity of Polkappa (zeige POLL Antikörper) during translesion synthesis of 10S(+)-trans-anti-benzo[a]pyrene diol epoxide-N(2)-deoxyguanine adducts lesions.

  2. Polk plays a predominant role in suppressing point mutations by carrying out error-free translesion DNA synthesis and contributes to the prevention of DNA strand breaks.

  3. The structural gap physically accommodates the bulky aromatic adduct and the N-clasp (zeige CLASRP Antikörper) is essential for the structural integrity and flexibility of Polkappa (zeige POLL Antikörper) during translesion synthesis.

  4. Polkappa (zeige POLL Antikörper) accumulates at laser-induced sites of DNA damage.

  5. Structural basis of Rev1-mediated assembly of a quaternary vertebrate translesion polymerase complex consisting of Rev1, heterodimeric polymerase (Pol) zeta, and Pol kappa (zeige POLL Antikörper)

  6. Data suggest that DNA polymerase kappa Polkapp (zeige POLL Antikörper)a functions in DNA interstrand crosslinks (ICLs) repair in (zeige APBB1 Antikörper) embryonic fibroblast cells (MEF), especially during the G0/G1 phases.

  7. solution structure of the polymerase kappa-Rev1 complex

  8. results are consistent with the notion that Pol kappa (zeige POLL Antikörper) is required for accurate translesion DNA synthesis past naturally occurring polycyclic guanine adducts, possibly generated by cholesterol and/or its metabolites.

  9. Polkappa (zeige POLL Antikörper) plays an important role in suppressing mutations at DNA lesions generated by benzo[a]pyrene, but not UV or x-ray irradiation.

  10. Rev7 competes directly with Pol kappa for binding to the Rev1 C-terminus.

Human Polymerase (DNA Directed) kappa (POLK) Interaktionspartner

  1. The structure of polK (zeige PAPD7 Antikörper) captured at the lesion-extension stage is reported: the enzyme is extending the primer strand after the base pair containing the BP-dG adduct in the template strand at the -1 position. PolK (zeige PAPD7 Antikörper) accommodates the BP adduct in the nascent DNA's minor groove and keeps the adducted DNA helix in a B-form.

  2. A report on the structure of human polkappa (zeige POLL Antikörper) in complex with a major benzo[a]pyrene adduct reveal a unique mechanism for accurate replication by translesion synthesis past the major bulky adduct.

  3. These studies revealed that POLK (zeige PAPD7 Antikörper) is a crucial host factor required for covalently closed circular DNA formation during a de novo HBV infection

  4. POLK (zeige PAPD7 Antikörper) protein polymorphisms may influence the risk of developing breast cancer among Chinese women.

  5. Somatic Mutations in Catalytic Core of POLK (zeige PAPD7 Antikörper) Reported in Prostate Cancer Alter Translesion DNA Synthesis

  6. POLK (zeige PAPD7 Antikörper) not only protects cells from genotoxic DNA lesions via DNA polymerase (zeige POLB Antikörper) activities, but also contributes to genome integrity by acting as a non-catalytic protein against oxidative damage caused by hydrogen peroxide and menadione.

  7. The structural dynamics of DinB1 changes upon substrate binding, noncognate DNA damage prevents the formation of the active conformation of DINB1.

  8. polymorphism of POLK (zeige PAPD7 Antikörper), an important gene in TLS (zeige FUS Antikörper), participates in platinum-chemotherapy tolerance and side-effect

  9. Mutations in PIP1 (zeige PAK1IP1 Antikörper) domain inhibits the stimulation of DNA synthesis by Polkappa (zeige POLL Antikörper) in the presence of proliferating cell nuclear antigen (zeige PCNA Antikörper), replication factor C, and replication protein A (zeige GPR153 Antikörper); and mutations in PIP2 have no effect on PCNA (zeige PCNA Antikörper)-dependent DNA synthesis.

  10. The truncation R219X was devoid of polymerase activity, and the E419G and Y432S variants showed much lower polymerase activity than wild-type POLK (zeige PAPD7 Antikörper).

Xenopus laevis Polymerase (DNA Directed) kappa (POLK) Interaktionspartner

  1. DNA polymerase kappa-dependent DNA synthesis at stalled replication forks is important for CHK1 (zeige CHEK1 Antikörper) activation.

  2. Data show that DNA polymerase kappa (Pol kappa (zeige POLL Antikörper)) is essential for replication-independent ICL repair (RIR (zeige APBB1 Antikörper)) of a site-specific DNA interstrand crosslinks (ICLs) lesion.

  3. pol kappa (zeige POLL Antikörper) (translesion synthesis TLS4) may assist pol eta (TLS3 or Rad30 (zeige POLH Antikörper)) in error-free extension during cyclobutane pyrimidine dimer bypass during DNA replication in oocyte extracts.

Polymerase (DNA Directed) kappa (POLK) Antigen-Profil

Beschreibung des Gens

External and internal DNA-damaging agents continually threaten the integrity of genetic material in cells. Although a variety of repair mechanisms exist to remove the resulting lesions, some lesions escape repair and block the replication machinery. Members of the Y family of DNA polymerases, such as POLK, permit the continuity of the replication fork by allowing replication through such DNA lesions. Each Y family polymerase has a unique DNA-damage bypass and fidelity profile. POLK is specialized for the extension step of lesion bypass (summary by Lone et al., 2007

Alternative names and synonyms associated with Polymerase (DNA Directed) kappa (POLK)

  • polymerase (DNA directed) kappa (POLK) Antikörper
  • polymerase (DNA directed) kappa (polk) Antikörper
  • DNA polymerase kappa (Tb11.01.0080) Antikörper
  • DNA polymerase kappa (Tb11.01.0010) Antikörper
  • DNA polymerase kappa (Tb11.01.0020) Antikörper
  • DNA polymerase kappa (Tb11.01.0030) Antikörper
  • DNA polymerase kappa (Tb11.01.0040) Antikörper
  • DNA polymerase kappa (Tb11.01.0050) Antikörper
  • DNA polymerase kappa (Tb11.12.0001) Antikörper
  • DNA polymerase kappa (Tb11.12.0002) Antikörper
  • DNA polymerase kappa (Tb11.12.0003) Antikörper
  • PAP associated domain containing 7 (Papd7) Antikörper
  • polymerase (DNA directed) kappa (Polk) Antikörper
  • polymerase (DNA directed), kappa (Polk) Antikörper
  • Dinb1 Antikörper
  • DINP Antikörper
  • DKFZp459J211 Antikörper
  • LAK-1 Antikörper
  • POLK Antikörper
  • POLQ Antikörper
  • Pols Antikörper
  • si:ch211-254o18.3 Antikörper
  • TRF4 Antikörper
  • TRF4-1 Antikörper

Bezeichner auf Proteinebene für POLK

DNA polymerase kappa , DNA-directed DNA polymerase kappa , polymerase (DNA directed) kappa , DNA polymerase kappa-like , DNA polymerase sigma , PAP-associated domain-containing protein 7 , polymerase (DNA directed) sigma , DINB protein , DINP , DNA damage-inducible protein b , DinB homolog 1

374003 Gallus gallus
448219 Xenopus (Silurana) tropicalis
705713 Macaca mulatta
3665078 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665080 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665081 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665082 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665083 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665084 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665087 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665088 Trypanosoma brucei brucei strain 927/4 GUTat10.1
3665089 Trypanosoma brucei brucei strain 927/4 GUTat10.1
100014509 Monodelphis domestica
100065534 Equus caballus
100077423 Ornithorhynchus anatinus
100173466 Pongo abelii
100352218 Oryctolagus cuniculus
100403269 Callithrix jacchus
100464732 Ailuropoda melanoleuca
562749 Danio rerio
210106 Mus musculus
51426 Homo sapiens
479180 Canis lupus familiaris
541218 Bos taurus
171525 Rattus norvegicus
461803 Pan troglodytes
100443121 Pongo abelii
446387 Xenopus laevis
100518650 Sus scrofa
27015 Mus musculus
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