anti-Exonuclease 1 (EXO1) Antikörper

Bezeichnung:
anti-Exonuclease 1 Antikörper (EXO1)
Auf www.antikoerper-online.de finden Sie aktuell 104 Exonuclease 1 (EXO1) Antikörper von 22 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Exonuclease 1 Proteine (6) und Exonuclease 1 Kits (2) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 120 Exonuclease 1 Produkte verfügbar.
Synonyme:
5730442G03Rik, ATWEX, ATWRNEXO, EXO1, exoi, EXONUCLEASE, F15D2.37, F15D2_37, F18A5.260, F18A5_260, fc16e04, HEX1, hExoI, Msa, Werner syndrome-like exonuclease, WEX, wu:fc16e04, zgc:55521

Meistgesuchte Reaktivitäten zu anti-Exonuclease 1 (EXO1) Antikörper

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anti-Human Exonuclease 1 Antikörper:

anti-Mouse (Murine) Exonuclease 1 Antikörper:

anti-Rat (Rattus) Exonuclease 1 Antikörper:

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Am meisten referenzierte anti-Exonuclease 1 Antikörper

  1. Human Polyclonal Exonuclease 1 Primary Antibody für IF, WB - ABIN389397 : Tishkoff, Amin, Viars, Arden, Kolodner: Identification of a human gene encoding a homologue of Saccharomyces cerevisiae EXO1, an exonuclease implicated in mismatch repair and recombination. in Cancer research 1998 (PubMed)
    Zeige alle 4 Referenzen für 389397

  2. Human Polyclonal Exonuclease 1 Primary Antibody für EIA, WB - ABIN358056 : Lee Bi, Nguyen, Barsky, Fernandes, Wilson: Molecular interactions of human Exo1 with DNA. in Nucleic acids research 2002 (PubMed)
    Zeige alle 4 Referenzen für 358056

  3. Human Polyclonal Exonuclease 1 Primary Antibody für ChIP, ICC - ABIN4309747 : Peterson, Li, Chait, Gottesman, Baer, Gautier: Cdk1 uncouples CtIP-dependent resection and Rad51 filament formation during M-phase double-strand break repair. in The Journal of cell biology 2011 (PubMed)
    Zeige alle 3 Referenzen für 4309747

  4. Human Polyclonal Exonuclease 1 Primary Antibody für ELISA, WB - ABIN408657 : Kim, Roh, Yoon, Kim, Park: MLH3 and EXO1 alterations in familial colorectal cancer patients not fulfilling Amsterdam criteria. in Cancer genetics and cytogenetics 2007 (PubMed)

Weitere Antikörper gegen Exonuclease 1 Interaktionspartner

Arabidopsis thaliana Exonuclease 1 (EXO1) Interaktionspartner

  1. has exonuclease properties that are similar to the human WRN protein

Human Exonuclease 1 (EXO1) Interaktionspartner

  1. The finding that a threading mechanism like that used by hFEN1 is also used by hEXO1 unifies the mode of operation for members of the 5'-nuclease superfamily that act on discontinuous substrates. As with hFEN1, intrinsic disorder of the arch region of the protein may explain how flaps can be threaded without a need for a coupled energy source.

  2. These findings indicate that the coupling of EXO1 activation with its eventual degradation is a timing mechanism that limits the extent of DNA end resection for accurate DNA repair.

  3. Mutations in the human EXO1 gene correlate with increased susceptibility to some cancers. This review summarizes recent studies on the enzymatic functions and biological roles of EXO1, its possible protective role against cancer and aging, and regulation of EXO1 by posttranslational modification. [review]

  4. These results suggest that Metnase (zeige SETMAR Antikörper) enhances Exo1-mediated exonuclease activity on the lagging strand DNA by facilitating Exo1 loading onto a single strand gap at the stalled replication fork.

  5. we present evidence that the inherited EXO1 polymorphism rs9350 may have a substantial influence on prostate cancer risk in Chinese people. We believe that the rs9350 could be a useful biomarker for assessing predisposition for and early diagnosis of prostate cancer.

  6. study concludes that Exo1 gene polymorphism Lys589Glu may be associated with an increased risk of colorectal cancer in the Polish population

  7. Mutations within the EXO1 gene are not associated with premature ovarian failure in Han Chinese women.

  8. EXO1 is more active on DNA at temperatures below 37 degrees C and this manifests as an increase in nuclease (zeige DCLRE1C Antikörper) activity.EXO1 preferentially cleaves one nucleotide inwards in a double stranded region of forked and nicked DNA flap (zeige ALOX5AP Antikörper) substrates.

  9. CRL4(Wdr70) regulates H2B monoubiquitination and facilitates Exo1-dependent DNA repair resection.

  10. MSH2 (zeige MSH2 Antikörper), MSH6 (zeige MSH6 Antikörper), and EXO1 genes were overexpressed in gastroesophageal cancers.

Mouse (Murine) Exonuclease 1 (EXO1) Interaktionspartner

  1. The results establish a key role for EXO1 in modulating the severity of hypomorphic MRE11 (zeige MRE11A Antikörper) complex mutations.

  2. Exo1-mediated HR is dispensable for stem cell function in quiescent HSC (zeige FUT1 Antikörper), whereas it is essential to HSC (zeige FUT1 Antikörper) response to DNA damage processing after cell cycle entry, and its loss is not compensated by intact NHEJ

  3. In contrast to Exo1(null/null) mice, Exo1(E109K/E109K) knockin mice retain mismatch repair activity and display normal class switch recombination and meiosis.

  4. RNAi-mediated EXO1 knockdown in mouse fibroblasts directly results in an alkylation-tolerant phenotype.

  5. Exo1 contributes to the metabolism of DNA ends during DNA double-strand breaks repair in B lymphocytes.

  6. Study documents the combinatorial action of Apollo (zeige DCLRE1B Antikörper), POT1b, CST (zeige CORT Antikörper), and the 5' exonuclease Exo1 in postreplicative telomere end processing in mouse cells, clarifying the mechanism by which the telomeric 3' overhang is generated and modulated.

  7. EXO1 can convert DNA nicks and point mutations into double-stranded DNA breaks for both core nonhomologous end-joining factors and alternative end-joining pathways of class-switch recombination.

  8. Apc (zeige APC Antikörper)(1638N) Exo1 Fen1 (zeige FEN1 Antikörper) mice survive longer (18 months)

  9. EXO1 contributes to DNA damage signal induction in mammalian cells, and deletion of Exo1 can prolong survival in the context of telomere dysfunction.

  10. Switch Junction Position Is Altered in Exo1-/- Mi

Exonuclease 1 (EXO1) Antigen-Profil

Beschreibung des Gens

This gene encodes a protein with 5' to 3' exonuclease activity as well as an RNase H activity. It is similar to the Saccharomyces cerevisiae protein Exo1 which interacts with Msh2 and which is involved in mismatch repair and recombination. Alternative splicing of this gene results in three transcript variants encoding two different isoforms.

Alternative names and synonyms associated with Exonuclease 1 (EXO1)

  • Werner Syndrome-like exonuclease (WRNEXO) Antikörper
  • hypothetical protein (Exonuclease) Antikörper
  • exonuclease I Exo1 (SJAG_01832) Antikörper
  • RNA exonuclease (PAS_chr1-1_0377) Antikörper
  • exonuclease 1 (EXO1) Antikörper
  • exonuclease 1 (exo1) Antikörper
  • exonuclease 1 (Exo1) Antikörper
  • exonuclease 1 (AT1G29630) Antikörper
  • 5730442G03Rik Antikörper
  • ATWEX Antikörper
  • ATWRNEXO Antikörper
  • EXO1 Antikörper
  • exoi Antikörper
  • EXONUCLEASE Antikörper
  • F15D2.37 Antikörper
  • F15D2_37 Antikörper
  • F18A5.260 Antikörper
  • F18A5_260 Antikörper
  • fc16e04 Antikörper
  • HEX1 Antikörper
  • hExoI Antikörper
  • Msa Antikörper
  • Werner syndrome-like exonuclease Antikörper
  • WEX Antikörper
  • wu:fc16e04 Antikörper
  • zgc:55521 Antikörper

Bezeichner auf Proteinebene für anti-Exonuclease 1 (EXO1) Antikörper

hypothetical protein , exonuclease I Exo1 , RNA exonuclease , exonuclease 1 , hExo1 , rad2 nuclease family member, homolog of S. cerevisiae exonuclease 1 , exonuclease I , mExo1 , exonuclease ExoI

GENE ID SPEZIES
827021 Arabidopsis thaliana
174842 Caenorhabditis elegans
7051049 Schizosaccharomyces japonicus yFS275
8196639 Komagataella pastoris GS115
457856 Pan troglodytes
706902 Macaca mulatta
100453255 Pongo abelii
100564366 Anolis carolinensis
9156 Homo sapiens
26909 Mus musculus
305000 Rattus norvegicus
406778 Danio rerio
839840 Arabidopsis thaliana
399140 Xenopus laevis
Ausgewählte Anbieter für anti-Exonuclease 1 (EXO1) Antikörper
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