anti-Vinculin (VCL) Antikörper

Bezeichnung:
anti-Vinculin Antikörper (VCL)
Auf www.antikoerper-online.de finden Sie aktuell 198 Vinculin (VCL) Antikörper von 29 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Vinculin Kits (39) und Vinculin Proteine (16) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 264 Vinculin Produkte verfügbar.
Synonyme:
9430097D22, AA571387, AI462105, AW545629, CG3299, CMD1W, CMH15, CT11081, DDBDRAFT_0186762, DDBDRAFT_0232320, DDB_0186762, DDB_0232320, Dmel\\CG3299, Dmvincp, EG:103B4.1, hm:zehn2160, im:6902790, LOC100228062, MV, MVCL, VCL, vcl-A, Vin, Vin2EF, vinc

Meistgesuchte Reaktivitäten zu anti-Vinculin (VCL) Antikörper

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anti-Human Vinculin Antikörper:

anti-Mouse (Murine) Vinculin Antikörper:

anti-Rat (Rattus) Vinculin Antikörper:

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Am meisten referenzierte anti-Vinculin Antikörper

  1. Human Polyclonal Vinculin Primary Antibody für IF (cc), IF (p) - ABIN719261 : Li, Sun, Yang, Hu, Jiang: Tanshinone II a protects against lipopolysaccharides-induced endothelial cell injury via Rho/Rho kinase pathway. in Chinese journal of integrative medicine 2014 (PubMed)
    Zeige alle 6 Referenzen für 719261

  2. Amphibian Monoclonal Vinculin Primary Antibody für ICC, IHC (fro) - ABIN269480 : Chianale, Cutrupi, Rainero, Baldanzi, Porporato, Traini, Filigheddu, Gnocchi, Santoro, Parolini, van Blitterswijk, Sinigaglia, Graziani: Diacylglycerol kinase-alpha mediates hepatocyte growth factor-induced epithelial cell scatter by regulating Rac activation and membrane ruffling. in Molecular biology of the cell 2007 (PubMed)
    Zeige alle 4 Referenzen für 269480

  3. Human Polyclonal Vinculin Primary Antibody für EIA, WB - ABIN359586 : Izard, Evans, Borgon, Rush, Bricogne, Bois: Vinculin activation by talin through helical bundle conversion. in Nature 2004 (PubMed)
    Zeige alle 3 Referenzen für 359586

  4. Human Polyclonal Vinculin Primary Antibody für EIA, WB - ABIN359587 : Moiseyeva, Weller, Zhidkova, Corben, Patel, Jasinska, Koteliansky, Critchley: Organization of the human gene encoding the cytoskeletal protein vinculin and the sequence of the vinculin promoter. in The Journal of biological chemistry 1993 (PubMed)
    Zeige alle 3 Referenzen für 359587

  5. Bat Polyclonal Vinculin Primary Antibody für WB - ABIN611567 : Hou, Schindler, Henzel, Ho, Brasseur, McKnight: An interleukin-4-induced transcription factor: IL-4 Stat. in Science (New York, N.Y.) 1994 (PubMed)
    Zeige alle 3 Referenzen für 611567

  6. Chicken Monoclonal Vinculin Primary Antibody für IHC (fro), IF - ABIN1109491 : Weller, Ogryzko, Corben, Zhidkova, Patel, Price, Spurr, Koteliansky, Critchley: Complete sequence of human vinculin and assignment of the gene to chromosome 10. in Proceedings of the National Academy of Sciences of the United States of America 1990 (PubMed)
    Zeige alle 2 Referenzen für 1109491

  7. Chicken Monoclonal Vinculin Primary Antibody für FACS, IHC (fro) - ABIN118973 : Asijee, Sturk, Bruin, Wilkinson, Ten Cate: Vinculin is a permanent component of the membrane skeleton and is incorporated into the (re)organising cytoskeleton upon platelet activation. in European journal of biochemistry / FEBS 1990 (PubMed)
    Zeige alle 2 Referenzen für 118973

Weitere Antikörper gegen Vinculin Interaktionspartner

Zebrafish Vinculin (VCL) Interaktionspartner

  1. Study show that zebrafish contain two homologous vinculin isoforms, of which the sequence of key functional domains is conserved with several higher vertebrate. Loss of both zygotic vcla and maternal contribution of vcla did not result in notable defects, while the additional loss of zygotic vclb is lethal only after embryonic stages. These data indicate that embryonic development in zebrafish can occur without vinculin.

Fruit Fly (Drosophila melanogaster) Vinculin (VCL) Interaktionspartner

  1. These findings demonstrate the crucial importance of the tight control of the activity of vinculin.

Human Vinculin (VCL) Interaktionspartner

  1. We identified mutations in VCL associated with Short segment Hirschsprung disease. Correction of this mutation in induced pluripotent stem cells using CRISPR/Cas9 editing, as well as the RET (zeige RET Antikörper) G731del mutation that causes Hirschsprung disease with total colonic aganglionosis, restored enteric neural crest cell function.

  2. This review discusses the current understanding of the roles of vinculin in cell-cell and cell-matrix adhesions. Emphasis is placed on the how vinculin is recruited, activated and regulated. [review]

  3. Study predicted the structure of the MAPK1 (zeige MAPK3 Antikörper)-vinculin binding interface using a combination of flexible docking and molecular dynamics simulations, and confirmed that the MAPK1 (zeige MAPK3 Antikörper)-vinculin interaction is mechanically regulated, and implicated a change in the vinculin D3-D4 cleft size upon vinculin activation as the basis for the conformational selectivity of MAPK1 (zeige MAPK3 Antikörper) binding toward open vinculin.

  4. These results suggest that vinculin promotes the nuclear localization of transcription factor TAZ (zeige TAZ Antikörper) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  5. The VCL-encoding protein was involved in cardiomyopathy that associated with hypertension, therefore our results suggest the rs4746172 of VCL may be a novel target for clinical interventions to reduce CVD risk by regulating blood pressure in male Chinese

  6. Three novel genes were identified as recurrently mutated; MYCN (zeige MYCN Antikörper), MYO5B and VCL, and mutations in these genes were exclusively found in malignant sympathetic paraganglioma tumors.

  7. roles and mechanisms of phospholipids in regulating the structure and function of vinculin and of its muscle-specific (zeige EIF3K Antikörper) metavinculin splice variant.

  8. Upon actin engagement, the N-terminal "strap" and helix 1 are displaced from the vinculin tail helical bundle to mediate actin bundling.

  9. This study defined a plastic relationship between vinculin-mediated tension and adhesion complex area that controls fundamental cell-matrix adhesion properties.

  10. Analysis showed that ITGB4 (zeige ITGB4 Antikörper) and VCL were upregulated in exosomes derived from taxane-resistant prostate cancer cells suggesting them as useful markers for progression of prostate cancer associated with taxane-resistance.

Mouse (Murine) Vinculin (VCL) Interaktionspartner

  1. results suggest that the vinculin-actin interaction participates in FA-mediated mechanotransduction

  2. These results suggest that vinculin promotes the nuclear localization of transcription factor TAZ (zeige TAZ Antikörper) to inhibit the adipocyte differentiation on rigid extracellular matrix.

  3. The results indicate that lipid rafts play an important role in extracellular matrix stiffness regulation of cell migration via expression vinculin and its interaction with vinexin alpha (zeige Sorbs3 Antikörper).

  4. Binding of vinculin to the R1-R3 region of the talin rod is important for focal adhesion stability.

  5. These data demonstrate that Src-mediated phosphorylation is necessary for vinculin activation, and that phosphorylation controls cytoskeletal mechanics by regulating force transmission between the actin cytoskeleton and focal adhesion proteins.

  6. results suggest that vinculin promotes directionally persistent cell migration and tension-dependent ECM (zeige MMRN1 Antikörper) remodeling in complex 3D environments by increasing cell-ECM (zeige MMRN1 Antikörper) adhesion and traction force generation.

  7. Force-dependent conformational switch of alpha-catenin (zeige CTNNA1 Antikörper) controls vinculin binding.

  8. Mutant vinculin expressing cells are altered in cell migration, which is accompanied by changes in cell adhesion.

  9. show that Src (zeige SRC Antikörper) phosphorylation of Y1065 within the C-terminal hairpin regulates Vt-mediated actin bundling and provide a detailed characterization of vinculin Y1065 mutations

  10. The E29R mutation might prime the vinculin head for F-actin binding, which results in higher cell stiffness, contractile force, and strengthening of focal adhesions.

Pig (Porcine) Vinculin (VCL) Interaktionspartner

  1. Results suggest that myosin VI (zeige MYO6 Antikörper) and vinculin form a molecular apparatus that generates cohesive cell-cell contacts in cultured mammalian epithelia.

Vinculin (VCL) Antigen-Profil

Beschreibung des Gens

Vinculin is a cytoskeletal protein associated with cell-cell and cell-matrix junctions, where it is thought to function as one of several interacting proteins involved in anchoring F-actin to the membrane. Defects in VCL are the cause of cardiomyopathy dilated type 1W. Dilated cardiomyopathy is a disorder characterized by ventricular dilation and impaired systolic function, resulting in congestive heart failure and arrhythmia. Multiple alternatively spliced transcript variants have been found for this gene, but the biological validity of some variants has not been determined.

Alternative names and synonyms associated with Vinculin (VCL)

  • vinculin (VCL) Antikörper
  • vinculin (vcl) Antikörper
  • vinculin A (vinA) Antikörper
  • Vinculin (Vinc) Antikörper
  • vinculin (CpipJ_CPIJ013873) Antikörper
  • vinculin (LOC100228062) Antikörper
  • vinculin (LOC100356093) Antikörper
  • vinculin (Vcl) Antikörper
  • vinculin (Bm1_37935) Antikörper
  • 9430097D22 Antikörper
  • AA571387 Antikörper
  • AI462105 Antikörper
  • AW545629 Antikörper
  • CG3299 Antikörper
  • CMD1W Antikörper
  • CMH15 Antikörper
  • CT11081 Antikörper
  • DDBDRAFT_0186762 Antikörper
  • DDBDRAFT_0232320 Antikörper
  • DDB_0186762 Antikörper
  • DDB_0232320 Antikörper
  • Dmel\\CG3299 Antikörper
  • Dmvincp Antikörper
  • EG:103B4.1 Antikörper
  • hm:zehn2160 Antikörper
  • im:6902790 Antikörper
  • LOC100228062 Antikörper
  • MV Antikörper
  • MVCL Antikörper
  • VCL Antikörper
  • vcl-A Antikörper
  • Vin Antikörper
  • Vin2EF Antikörper
  • vinc Antikörper

Bezeichner auf Proteinebene für anti-Vinculin (VCL) Antikörper

vinculin , CG3299-PA , Vinc-PA , vinculin at 2EF , vinculin-like , metavinculin , vinculin/metavinculin

GENE ID SPEZIES
100064165 Equus caballus
450531 Pan troglodytes
552980 Danio rerio
8625369 Dictyostelium discoideum AX4
31201 Drosophila melanogaster
6047004 Culex quinquefasciatus
100036705 Xenopus (Silurana) tropicalis
100228062 Taeniopygia guttata
100410985 Callithrix jacchus
100476722 Ailuropoda melanoleuca
714312 Macaca mulatta
721921 Macaca mulatta
100075715 Ornithorhynchus anatinus
100583187 Nomascus leucogenys
7414 Homo sapiens
396422 Gallus gallus
100356093 Oryctolagus cuniculus
22330 Mus musculus
305679 Rattus norvegicus
783645 Bos taurus
373770 Xenopus laevis
100302597 Meleagris gallopavo
479252 Canis lupus familiaris
100357160 Oryctolagus cuniculus
396974 Sus scrofa
100722183 Cavia porcellus
101121312 Ovis aries
6102471 Brugia malayi
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