anti-Caspase 12 (CASP12) Antikörper

anti-Caspase 12 (Gene/pseudogene) Antikörper (CASP12)
Auf finden Sie aktuell 26 Caspase 12 (Gene/pseudogene) (CASP12) Antikörper von 11 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen Caspase 12 Kits (9) und und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 37 Caspase 12 Produkte verfügbar.
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CASP12 120329

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Am meisten referenzierte anti-Caspase 12 Antikörper

  1. Human Polyclonal Caspase 12 Primary Antibody für WB - ABIN306744 : Nakagawa, Zhu, Morishima, Li, Xu, Yankner, Yuan: Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-beta. in Nature 2000 (PubMed)
    Zeige alle 3 Referenzen für 306744

  2. Human Polyclonal Caspase 12 Primary Antibody für WB - ABIN306745 : Mehmet: Caspases find a new place to hide. in Nature 2000 (PubMed)
    Zeige alle 3 Referenzen für 306745

  3. Human Polyclonal Caspase 12 Primary Antibody für IHC (p), WB - ABIN3042658 : Ding, Zou, Li, Tian, Abdelalim, Du, She, Wang, Tan, Wang, Chen, Lv, Chang: Study of histopathological and molecular changes of rat kidney under simulated weightlessness and resistance training protective effect. in PLoS ONE 2011 (PubMed)
    Zeige alle 2 Referenzen für 3042658

Weitere Antikörper gegen Caspase 12 Interaktionspartner

Human Caspase 12 (Gene/pseudogene) (CASP12) Interaktionspartner

  1. Endoplasmic reticulum stress related factor ATF6 (zeige ATF6 Antikörper) and caspase-12 trigger apoptosis in neonatal hypoxic-ischemic encephalopathy.

  2. Expression of caspase-12 was linked to decreased systemic and adipose tissue inflammation in a cohort of African American obese children.

  3. We found that RNA interference-induced Caspase-12 silencing increased NOD1 (zeige NOD1 Antikörper), hBD1 (zeige DEFB1 Antikörper) and hBD2 (zeige DEFB4 Antikörper) expression

  4. EtOH-induced activation of caspase-12 could be one of the underlying mechanisms of hepatocyte apoptosis.

  5. Distribution of CASP12 alleles (#rs497116) in African-Americans (AA) with rheumatoid arthritis (RA). There was no difference in the overall distribution of genotypes within AA with RA, but homozygous patients had lower baseline joint-narrowing scores.

  6. CASPASE-12 does not influence the susceptibility to Candida sepsis, nor has any effect on the serum cytokine concentrations in Candida sepsis patients during the course of infection.

  7. examines the role that CASP12 plays in down-regulating inflammation, we hypothesize that pathogens which exploit the inflammatory response are restrained by an active CASP12 gene product

  8. caspase 12 has acquired deleterious mutations

  9. Pathways involving this enzyme are involved in a neurodegenerative disease in vivo, and thus offer novel potential targets for the treatment of prion (zeige PRNP Antikörper) disorders.

  10. Na/Ca exchanger (zeige SLC8A1 Antikörper) overexpression activates caspase-12

Caspase 12 (CASP12) Antigen-Profil

Beschreibung des Gens

Caspases are cysteine proteases that cleave C-terminal aspartic acid residues on their substrate molecules. This gene is most highly related to members of the ICE subfamily of caspases that process inflammatory cytokines. In rodents, the homolog of this gene mediates apoptosis in response to endoplasmic reticulum stress. However, in humans this gene contains a polymorphism for the presence or absence of a premature stop codon. The majority of human individuals have the premature stop codon and produce a truncated non-functional protein. The read-through codon occurs primarily in individuals of African descent and carriers have endotoxin hypo-responsiveness and an increased susceptibility to severe sepsis. Several alternatively spliced transcript variants have been noted for this gene.

Alternative names and synonyms associated with Caspase 12 (CASP12)

  • caspase 12 (gene/pseudogene) (CASP12) Antikörper
  • CASP-12 Antikörper
  • CASP12P1 Antikörper

Bezeichner auf Proteinebene für CASP12

caspase 12 pseudogene 1 , inactive caspase-12

120329 Homo sapiens
100506742 Homo sapiens
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