anti-BCL2L1 (BCL2L1) Antikörper

Bezeichnung:
anti-BCL2-Like 1 Antikörper (BCL2L1)
Auf www.antikoerper-online.de finden Sie aktuell 516 BCL2-Like 1 (BCL2L1) Antikörper von 37 unterschiedlichen Herstellern. Zusätzlich bieten wir Ihnen BCL2L1 Kits (22) und BCL2L1 Proteine (17) und viele weitere Produktgruppen zu diesem Protein an. Insgesamt sind aktuell 579 BCL2L1 Produkte verfügbar.
Synonyme:
Bcl(X)L, bcl-X, bcl-x(l), bcl-xl, BCL-XL/S, Bcl-Xs, Bcl2l, BCL2L1, Bclx, BCLXL, BCLXS, PPP1R52, xR11
Alle Antikörper anzeigen Gen GeneID UniProt
BCL2L1 60480  
BCL2L1 598 Q07817
BCL2L1 24888 P53563

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Weitere Synonyme anzeigen

Meistgesuchte Reaktivitäten zu anti-BCL2L1 (BCL2L1) Antikörper

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anti-Mouse (Murine) BCL2L1 Antikörper:

anti-Human BCL2L1 Antikörper:

anti-Rat (Rattus) BCL2L1 Antikörper:

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Am meisten referenzierte anti-BCL2L1 Antikörper

  1. Human Monoclonal BCL2L1 Primary Antibody für WB - ABIN967300 : Hsu, Wolter, Youle: Cytosol-to-membrane redistribution of Bax and Bcl-X(L) during apoptosis. in Proceedings of the National Academy of Sciences of the United States of America 1997 (PubMed)
    Zeige alle 4 Referenzen für 967300

  2. Human Polyclonal BCL2L1 Primary Antibody für IHC, ELISA - ABIN1531788 : Cheng, Levine, Boise, Thompson, Hardwick: Bax-independent inhibition of apoptosis by Bcl-XL. in Nature 1996 (PubMed)
    Zeige alle 3 Referenzen für 1531788

  3. Human Monoclonal BCL2L1 Primary Antibody für FACS, IF - ABIN180627 : Hsu, Youle: Nonionic detergents induce dimerization among members of the Bcl-2 family. in The Journal of biological chemistry 1997 (PubMed)
    Zeige alle 3 Referenzen für 180627

  4. Human Polyclonal BCL2L1 Primary Antibody für IP, WB - ABIN223050 : Cordiali-Fei, Ardigo, Mastroianni, Giuliani, D Agosto, Bordignon, Trento, Vento, Berardesca: Serum cytokines and biohumoral immunological characterization of psoriatic patients in long term etanercept treatment. in International journal of immunopathology and pharmacology 2008 (PubMed)
    Zeige alle 3 Referenzen für 223050

  5. Human Polyclonal BCL2L1 Primary Antibody für IHC, ELISA - ABIN1532818 : Sattler, Liang, Nettesheim, Meadows, Harlan, Eberstadt, Yoon, Shuker, Chang, Minn, Thompson, Fesik: Structure of Bcl-xL-Bak peptide complex: recognition between regulators of apoptosis. in Science (New York, N.Y.) 1997 (PubMed)
    Zeige alle 3 Referenzen für 1532818

  6. Human Polyclonal BCL2L1 Primary Antibody für IHC, ELISA - ABIN1533140 : Boise, González-García, Postema, Ding, Lindsten, Turka, Mao, Nuñez, Thompson: bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death. in Cell 1993 (PubMed)
    Zeige alle 2 Referenzen für 1533140

  7. Human Polyclonal BCL2L1 Primary Antibody für IHC, ELISA - ABIN1532107 : Deloukas, Matthews, Ashurst, Burton, Gilbert, Jones, Stavrides, Almeida, Babbage, Bagguley, Bailey, Barlow, Bates, Beard, Beare, Beasley, Bird, Blakey, Bridgeman, Brown, Buck, Burrill, Butler, Carder et al.: The DNA sequence and comparative analysis of human chromosome 20. ... in Nature 2002 (PubMed)
    Zeige alle 2 Referenzen für 1532107

  8. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody für WB - ABIN2779336 : ONeill, Manion, Maguire, Hockenbery: BCL-XL dimerization by three-dimensional domain swapping. in Journal of molecular biology 2006 (PubMed)

  9. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody für WB - ABIN2774598 : Bachelor, Bowden: Ultraviolet A-induced modulation of Bcl-XL by p38 MAPK in human keratinocytes: post-transcriptional regulation through the 3'-untranslated region. in The Journal of biological chemistry 2004 (PubMed)

  10. Cow (Bovine) Polyclonal BCL2L1 Primary Antibody für WB - ABIN2792119 : Xu, Xu, Palmer, Reed: BI-1 regulates endoplasmic reticulum Ca2+ homeostasis downstream of Bcl-2 family proteins. in The Journal of biological chemistry 2008 (PubMed)

Weitere Antikörper gegen BCL2L1 Interaktionspartner

Mouse (Murine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. Bcl-xL deficiency induced apoptosis in a select population of differentiated neurons and led to severe neurobehavioral abnormalities.

  2. loss of PUMA (zeige BBC3 Antikörper) had no impact on the loss of platelets caused by loss of BCL-XL. It therefore remains to be established whether other BH3-only (zeige BBC3 Antikörper) proteins play a critical role in induction of apoptosis in platelets or whether their death is controlled solely by the interactions between BCL-XL with BAK (zeige BAK1 Antikörper) and BAX (zeige BAX Antikörper).

  3. MLF1 (zeige MLF1 Antikörper) is negatively regulated by 14-3-3 (zeige YWHAQ Antikörper) via binding to, and blocking, MLF1 (zeige MLF1 Antikörper)'s Bcl-2 (zeige BCL2 Antikörper) homology domain 3 and thereby preventing Bcl-XL from associating with MLF1 (zeige MLF1 Antikörper).

  4. Genetic and pharmacological inhibition of BCL-W (zeige BCL2L2 Antikörper) and BCL-XL causes directed elimination of senescent cells.

  5. Valproic acid sensitized TRAIL-resistant papillary thyroid carcinoma cells to apoptotic cell death through involvement of Nrf2 (zeige NFE2L2 Antikörper) and Bcl-xL.

  6. The influence of chronic ethanol consumption on the expression of the Bdnf (zeige BDNF Antikörper), Bax (zeige BAX Antikörper), Bcl-xL, and CASP3 (zeige CASP3 Antikörper) genes was studied in the brain structures of B6-1473C (C/C) and B6-1473G (G/G) mice that had been obtained on the base of the C57BL/6 strain.

  7. despite its role in Bax (zeige BAX Antikörper) inhibition, Bcl-xL also primes mitochondria to permeabilization and cytochrome c (zeige CYCS Antikörper) release.

  8. These findings indicate that eosinophil survival is largely regulated by betac chain-induced NF-kappaB (zeige NFKB1 Antikörper) activation and subsequent induction of Bcl-x

  9. these data indicate that beta-cell apoptosis is, in part, attributable to the modulation of 5'SS selection in the Bcl-x pre-mRNA by bioactive lipids modulated by iPLA2beta (zeige PLA2G6 Antikörper).

  10. only loss of both Bclx alleles markedly forestalled tumorigenesis, loss of a single Bim (zeige BCL2L11 Antikörper) allele overcame this blockade.

Human BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. Bcl-xL inhibits GAS-induced autophagy directly by suppressing autophagosome-lysosome fusion and indirectly by suppressing GAS internalization via interaction with Beclin 1 (zeige BECN1 Antikörper)-UVRAG (zeige UVRAG Antikörper).

  2. The combination of 2-deoxyglucose (2-DG) and ABT-199 initiated cell death through the reduction of myeloid cell leukemia sequence 1 protein (Mcl-1 (zeige MCL1 Antikörper)) expression and c-Jun N-terminal kinase 1 (JNK1 (zeige MAPK8 Antikörper)) activation and subsequent Bcl-xL protein degradation.

  3. Bcl-xL is an exosomal caspase-3 (zeige CASP3 Antikörper) substrate and that this processing is required for the uptake of exosomes by recipient cells.

  4. dynamic Bcl-xL(S49) and (S62) phosphorylation/dephosphorylation cycles are important in the maintenance of chromosome integrity during mitosis in normal cells

  5. in addition to MCL-1 (zeige MCL1 Antikörper), BCL-XL is heterogeneously expressed in HMCLs and patient samples. The expression profile of BCL-XL relative to BCL-2 (zeige BCL2 Antikörper) and MCL-1 (zeige MCL1 Antikörper) may be an important predictor of response to venetoclax sensitivity as a monotherapy and in combination with bortezomib.

  6. Mono treatment with lexatumumab was not sufficient to induce apoptosis in pancreatic cancer cells, whereas focal adhesion kinase inhibitor PF573228 significantly sensitized lexatumumab-induced apoptosis. Western blotting analysis revealed that lexatumumab and PF573228 combination treatment increased death receptor 5 (zeige TNFRSF10B Antikörper) but decreased Bcl-xL expression.

  7. Reduced lifetimes of the donor were partially restored by coexpression of HIF-1alpha (zeige HIF1A Antikörper) or Bcl-xL, binding proteins of IPAS (zeige HIF3A Antikörper) in the nucleus and mitochondria, respectively.

  8. mechanistic studies, inhibition of SRC (zeige SRC Antikörper) and PKCdelta (zeige PKCd Antikörper) completely ablated the ability of MDA-7/IL-24 (zeige IL24 Antikörper) to reduce the Bcl-x(L)/(s) mRNA ratio and cell viability. These findings show that Bcl-x(s) expression is an important mediator of MDA-7/IL-24 (zeige IL24 Antikörper)-induced cytotoxicity requiring the SRC (zeige SRC Antikörper)/PKCdelta (zeige PKCd Antikörper) signaling axis in NSCLC cells.

  9. Resistance induced in newly formed cancer stem cells is mediated by the anti-apoptotic molecule BCL-XL and inhibition of BCL-XL with the BH3 mimetic ABT-737 sensitizes these cancer cells toward chemotherapy.

  10. we discovered that deletions involving the PARK2 (zeige PARK2 Antikörper) gene are significantly anti-correlated with focal amplifications of the gene encoding BCL-XL.

Pig (Porcine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. interleukin-6 (zeige IL6 Antikörper), endothelin ET-1 (zeige EDN1 Antikörper), and apoptotic Bak (zeige BAK1 Antikörper) and Bcl-XL genes have roles in small bowel transplantation, in a swine model of ischemia and reperfusion injury

  2. Bcl-xL was significantly decreased in haploid parthenotes compared with the diploid parthenotes. These results suggest that the haploid state affects apoptosis-related gene expression which results in increased apoptosis

  3. CONCLUSION(S): (1) Apoptosis is involved in follicular atresia; (2) Bcl-2 (zeige BCL2 Antikörper) is induced by warm ischemia; and (3) cryopreservation insult does not alter the apoptotic signals with short tissue preparation time.

  4. Bcl-Xl deamidation and methylation has a role in protein isoaspartate methyltransferase prevention of apoptosis induced by oxidative stress in endothelial cells

  5. Data show that cysteine significantly reduced the expression of pro-inflammatory cytokines, including TNF-alpha (zeige TNF Antikörper), IL-6 (zeige IL6 Antikörper), IL-12p40, IL-1beta (zeige IL1B Antikörper), and resulted in increased expression of the apoptosis initiator caspase-8 (zeige CASP8 Antikörper) and bcl2L1.

Cow (Bovine) BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. amplification and characterization of partial regions of exons 2 and 3 of the bovine BCL2L1 gene

  2. Data show that Bcl-x(L) expression is increased in the pulmonary artery undergoing chronic pulmonary vascular remodeling.

Rabbit BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. This study leads to conclude that BCLXL peak expression at the zygotic genome activation phase may be a requirement for embryo development

  2. In this study evidence is provided that exogenous PGF2alpha differentially modulates luteal expression of BCL2L1 transcripts and protein depending on luteal stage.

Xenopus laevis BCL2-Like 1 (BCL2L1) Interaktionspartner

  1. repression of radiation-induced apoptosis by overexpression of Bcl-xL during embryonic development depends upon the timing of its expression and post-translational events that enable the protein to become effective

BCL2L1 Antigen-Profil

Beschreibung des Gens

The protein encoded by this gene belongs to the BCL-2 protein family. BCL-2 family members form hetero- or homodimers and act as anti- or pro-apoptotic regulators that are involved in a wide variety of cellular activities. The proteins encoded by this gene are located at the outer mitochondrial membrane, and have been shown to regulate outer mitochondrial membrane channel (VDAC) opening. VDAC regulates mitochondrial membrane potential, and thus controls the production of reactive oxygen species and release of cytochrome C by mitochondria, both of which are the potent inducers of cell apoptosis. Two alternatively spliced transcript variants, which encode distinct isoforms, have been reported. The longer isoform acts as an apoptotic inhibitor and the shorter form acts as an apoptotic activator.

Alternative names and synonyms associated with BCL2L1

  • BCL2-like 1 (bcl2l1) Antikörper
  • BCL2-like 1 (BCL2L1) Antikörper
  • BCL2-like 1 (LOC100224900) Antikörper
  • transgene insertion 2, Craig B Thompson (Tg(BCL2L1)2Cbt) Antikörper
  • BCL2-like 1 (Bcl2l1) Antikörper
  • Bcl2-like 1 (Bcl2l1) Antikörper
  • Bcl(X)L Antikörper
  • bcl-X Antikörper
  • bcl-x(l) Antikörper
  • bcl-xl Antikörper
  • BCL-XL/S Antikörper
  • Bcl-Xs Antikörper
  • Bcl2l Antikörper
  • BCL2L1 Antikörper
  • Bclx Antikörper
  • BCLXL Antikörper
  • BCLXS Antikörper
  • PPP1R52 Antikörper
  • xR11 Antikörper

Bezeichner auf Proteinebene für anti-BCL2-Like 1 (BCL2L1) Antikörper

BCL2-like 1 , apoptosis regulator Bcl-X , bcl-2-like protein 1 , protein phosphatase 1, regulatory subunit 52 , B-cell leukemia/lymphoma x , anti-apoptosis regulatory protein , bcl2-L-1 , B cell lymphoma 2 like , B cell lymphoma like X , anti-apoptotic Bcl-xL , BCL2-like protein 1 , Bcl-X , BCLX protein , apoptosis regulator R11

GENE ID SPEZIES
447991 Xenopus (Silurana) tropicalis
458156 Pan troglodytes
100224900 Taeniopygia guttata
60480 Mus musculus
598 Homo sapiens
12048 Mus musculus
24888 Rattus norvegicus
397536 Sus scrofa
403618 Canis lupus familiaris
282152 Bos taurus
100008875 Oryctolagus cuniculus
493701 Felis catus
443061 Ovis aries
373954 Gallus gallus
398251 Xenopus laevis
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