GABPA Antikörper (AA 120-190)

Produktnummer ABIN969163

Dieser Maus Monoklonal Antikörper detektiert spezifisch GABPA in WB, ELISA und ICC. Es zeigt Reaktivität gegenüber Proben von Human und Maus. Es wurde in 2+ Publikationen zitiert.

Kurzübersicht für GABPA Antikörper (AA 120-190) (ABIN969163)

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Reaktivität: Human, Maus

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser GABPA Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunocytochemistry (ICC)

Klon: 8C1B10

Produktdetails anti-GABPA Antikörper

Bindungsspezifität: AA 120-190

Verwendungszweck: GABPA Antibody

Aufreinigung: Ascitic fluid

Immunogen: Purified recombinant fragment of human GABPA (aa120-190) expressed in E. Coli.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise:

ELISA: 1/10000

ICC: 1/200 - 1/1000

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Buffer: Ascitic fluid containing 0.03 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze/thaw cycles.

Referenzen für anti-GABPA Antikörper (ABIN969163)

Sawada, Simizu, Suzuki, Sawa, Goto, Hasegawa, Imai, Watanabe, Handa: "Synergistic transcriptional activation by hGABP and select members of the activation transcription factor/cAMP response element-binding protein family." in: The Journal of biological chemistry, Vol. 274, Issue 50, pp. 35475-82, (2000) (PubMed).

Vogel, Kristie: "The novel coactivator C1 (HCF) coordinates multiprotein enhancer formation and mediates transcription activation by GABP." in: The EMBO journal, Vol. 19, Issue 4, pp. 683-90, (2000) (PubMed).

Details zu GABPA

Target: GABPA (GA Binding Protein Transcription Factor, alpha Subunit 60kDa (GABPA))

Andere Bezeichnung: GABPA

Hintergrund: GABPA: GA binding protein transcription factor, alpha subunit 60 kDa. It is one of three GA-binding protein transcription factor subunits which functions as a DNA-binding subunit. Since this subunit shares identity with a subunit encoding the nuclear respiratory factor 2 gene, it is likely involved in activation of cytochrome oxidase expression and nuclear control of mitochondrial function. This subunit also shares identity with a subunit constituting the transcription factor E4TF1, responsible for expression of the adenovirus E4 gene. Because of its chromosomal localization and ability to form heterodimers with other polypeptides, it may play a role in the Down Syndrome phenotype.

Molekulargewicht: 51 kDa

Gen-ID: 2551

UniProt: Q06546

Pathways: Myometrial Relaxation and Contraction