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ANKS1B Antikörper (AA 107-268)

ANKS1B Reaktivität: Human, Maus, Ratte, Huhn WB, IP, IHC (p), IF Wirt: Maus Monoclonal 5-EB1 unconjugated
Produktnummer ABIN968021
  • Target Alle ANKS1B Antikörper anzeigen
    ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))
    Bindungsspezifität
    • 7
    • 6
    • 6
    • 6
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 107-268
    Reaktivität
    • 41
    • 24
    • 20
    • 3
    • 3
    • 3
    • 3
    • 2
    • 1
    • 1
    • 1
    • 1
    Human, Maus, Ratte, Huhn
    Wirt
    • 40
    • 1
    Maus
    Klonalität
    • 40
    • 1
    Monoklonal
    Konjugat
    • 17
    • 3
    • 3
    • 3
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser ANKS1B Antikörper ist unkonjugiert
    Applikation
    • 39
    • 16
    • 15
    • 14
    • 5
    • 5
    • 2
    • 1
    Western Blotting (WB), Immunoprecipitation (IP), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (IF)
    Kreuzreaktivität
    Huhn, Maus, Ratte (Rattus)
    Produktmerkmale
    1. Since applications vary, each investigator should titrate the reagent to obtain optimal results.
    2. Please refer to us for technical protocols.
    3. Caution: Sodium azide yields highly toxic hydrazoic acid under acidic conditions. Dilute azide compounds in running water before discarding to avoid accumulation of potentially explosive deposits in plumbing.
    4. Source of all serum proteins is from USDA inspected abattoirs located in the United States.
    Aufreinigung
    The monoclonal antibody was purified from tissue culture supernatant or ascites by affinity chromatography.
    Immunogen
    Human EB1 aa. 107-268
    Klon
    5-EB1
    Isotyp
    IgG1
    Top Product
    Discover our top product ANKS1B Primärantikörper
  • Kommentare

    Related Products: ABIN968536, ABIN967389

    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Konzentration
    250 μg/mL
    Buffer
    Aqueous buffered solution containing BSA, glycerol, and ≤0.09 % sodium azide.
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
    Informationen zur Lagerung
    Store undiluted at -20°C.
  • Etienne-Manneville, Hall: "Cdc42 regulates GSK-3beta and adenomatous polyposis coli to control cell polarity." in: Nature, Vol. 421, Issue 6924, pp. 753-6, (2003) (PubMed).

    Askham, Vaughan, Goodson, Morrison: "Evidence that an interaction between EB1 and p150(Glued) is required for the formation and maintenance of a radial microtubule array anchored at the centrosome." in: Molecular biology of the cell, Vol. 13, Issue 10, pp. 3627-45, (2002) (PubMed).

    Komarova, Akhmanova, Kojima, Galjart, Borisy: "Cytoplasmic linker proteins promote microtubule rescue in vivo." in: The Journal of cell biology, Vol. 159, Issue 4, pp. 589-99, (2002) (PubMed).

    Mamane, Grandvaux, Hernandez, Sharma, Innocente, Lee, Azimi, Lin, Hiscott: "Repression of IRF-4 target genes in human T cell leukemia virus-1 infection." in: Oncogene, Vol. 21, Issue 44, pp. 6751-65, (2002) (PubMed).

    Su, Huang, Fair, Powell, Heston: "Alternatively spliced variants of prostate-specific membrane antigen RNA: ratio of expression as a potential measurement of progression." in: Cancer research, Vol. 55, Issue 7, pp. 1441-3, (1995) (PubMed).

  • Target
    ANKS1B (Ankyrin Repeat and Sterile alpha Motif Domain Containing 1B (ANKS1B))
    Andere Bezeichnung
    EB1 (ANKS1B Produkte)
    Synonyme
    AIDA antikoerper, AIDA-1 antikoerper, ANKS2 antikoerper, EB-1 antikoerper, EB1 antikoerper, cajalin-2 antikoerper, AIDA-1b antikoerper, C030032C09Rik antikoerper, E530015N03Rik antikoerper, ENSMUSG00000078431 antikoerper, Gm10937 antikoerper, Gm1555 antikoerper, RGD1565556 antikoerper, si:ch211-146a9.3 antikoerper, si:dkey-11k24.3 antikoerper, Anks1b antikoerper, ankyrin repeat and sterile alpha motif domain containing 1B antikoerper, ankyrin repeat and sterile alpha motif domain-containing protein 1B antikoerper, ANKS1B antikoerper, Anks1b antikoerper, anks1b antikoerper, LOC100717398 antikoerper
    Hintergrund
    Familial adenomatous polyposis is an autosomal inherited disease characterized by mutations in the APC (adenomatous polyposis coli) gene. Individuals with this disease are predisposed to colorectal polyps and cancer. It has been proposed that disruption of the APC gene plays a role in the disease. APC is a large coiled-coil protein that interacts, via its carboxy terminus, with catenins and with the protein, EB1. This 30 kDa protein was discovered as a result of its strong binding to the C-terminal domain of APC. Like the APC-binding proteins beta-Catenin and pp120Cas, EB1 may play an essential role in modulating APC activity and tumorigenesis. This antibody is routinely tested by western blot analysis.
    Molekulargewicht
    30 kDa
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