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Acetylcholinesterase Antikörper (N-Term)

AChE Reaktivität: Human IHC Wirt: Kaninchen Polyclonal unconjugated
Produktnummer ABIN965502
  • Target Alle Acetylcholinesterase (AChE) Antikörper anzeigen
    Acetylcholinesterase (AChE)
    Bindungsspezifität
    • 15
    • 6
    • 5
    • 5
    • 5
    • 4
    • 4
    • 3
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    N-Term
    Reaktivität
    • 51
    • 34
    • 33
    • 18
    • 9
    • 7
    • 3
    • 3
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Human
    Wirt
    • 91
    • 8
    • 8
    • 1
    Kaninchen
    Klonalität
    • 101
    • 7
    Polyklonal
    Konjugat
    • 55
    • 22
    • 8
    • 6
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    Dieser Acetylcholinesterase Antikörper ist unkonjugiert
    Applikation
    • 87
    • 49
    • 22
    • 17
    • 13
    • 13
    • 11
    • 8
    • 8
    • 5
    • 5
    • 4
    • 4
    • 4
    • 2
    • 2
    • 1
    Immunohistochemistry (IHC)
    Aufreinigung
    Purified by antigen-specific affinity chromatography.
    Immunogen
    Polyclonal antibody produced in rabbits immunizing with a synthetic peptide corresponding to N-terminal residues of human ACHE (N-terminal extended acetylcholinesterase)
    Top Product
    Discover our top product AChE Primärantikörper
  • Applikationshinweise
    ELISA, Western blotting: 1µg/ml for 2hrs.
    Beschränkungen
    Nur für Forschungszwecke einsetzbar
  • Format
    Liquid
    Buffer
    This antibody is stored in PBS, 50% glycerol
    Konservierungsmittel
    Sodium azide
    Vorsichtsmaßnahmen
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Lagerung
    -20 °C
  • Meshorer, Toiber, Zurel, Sahly, Dori, Cagnano, Schreiber, Grisaru, Tronche, Soreq: "Combinatorial complexity of 5' alternative acetylcholinesterase transcripts and protein products." in: The Journal of biological chemistry, Vol. 279, Issue 28, pp. 29740-51, (2004) (PubMed).

    Velan, Grosfeld, Kronman, Leitner, Gozes, Lazar, Flashner, Marcus, Cohen, Shafferman: "The effect of elimination of intersubunit disulfide bonds on the activity, assembly, and secretion of recombinant human acetylcholinesterase. Expression of acetylcholinesterase Cys-580----Ala mutant." in: The Journal of biological chemistry, Vol. 266, Issue 35, pp. 23977-84, (1992) (PubMed).

    Shafferman, Kronman, Flashner, Leitner, Grosfeld, Ordentlich, Gozes, Cohen, Ariel, Barak: "Mutagenesis of human acetylcholinesterase. Identification of residues involved in catalytic activity and in polypeptide folding." in: The Journal of biological chemistry, Vol. 267, Issue 25, pp. 17640-8, (1992) (PubMed).

    Soreq, Ben-Aziz, Prody, Seidman, Gnatt, Neville, Lieman-Hurwitz, Lev-Lehman, Ginzberg, Lipidot-Lifson: "Molecular cloning and construction of the coding region for human acetylcholinesterase reveals a G + C-rich attenuating structure." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 87, Issue 24, pp. 9688-92, (1991) (PubMed).

  • Target
    Acetylcholinesterase (AChE)
    Andere Bezeichnung
    ACHE (AChE Produkte)
    Synonyme
    ACEE antikoerper, ARACHE antikoerper, N-ACHE antikoerper, YT antikoerper, Ache antikoerper, GB14873 antikoerper, zgc:92550 antikoerper, ACE antikoerper, Dsim\\GD20515 antikoerper, GD20515 antikoerper, dsim_GLEANR_4292 antikoerper, ache antikoerper, mE1a antikoerper, mE1b antikoerper, mE1c antikoerper, mE1c-long antikoerper, mE1d antikoerper, mE1d' antikoerper, mE1e antikoerper, arache antikoerper, n-ache antikoerper, acetylcholinesterase (Cartwright blood group) antikoerper, acetylcholinesterase 2 antikoerper, acetylcholinesterase antikoerper, Acetylcholine esterase antikoerper, acetylcholinesterase (Cartwright blood group) L homeolog antikoerper, collagen type I alpha 2 chain antikoerper, ACHE antikoerper, AChE-2 antikoerper, Ache antikoerper, ache antikoerper, Dsim\Ace antikoerper, ache.L antikoerper, COL1A2 antikoerper, ACE-1 antikoerper
    Hintergrund
    ACHE(acetylcholinesterase) rapidly hydrolyzes choline released into the synapse. ACHE interacts with PRIMA1. The interaction with PRIMA1 is required to anchor it to the basal lamina of cells and organize into tetramers. ACHE is responsible for the Yt blood group system. The molecular basis of the Yt(a)=Yt1/ Yt(b)=Yt2 blood group antigens is a single variation in position 353, His-353 corresponds to Yt(a) and the rare variant with Asn-353 to Yt(b).
    Pathways
    Skeletal Muscle Fiber Development
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