Factor VIII Antikörper (C-Term)

Produktnummer ABIN929428

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch Factor VIII in WB. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für Factor VIII Antikörper (C-Term) (ABIN929428)

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Factor VIII Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-Factor VIII Antikörper

Bindungsspezifität: C-Term

Aufreinigung: Purified

Immunogen: F8 antibody was raised in rabbit using the C terminal of F8 as the immunogen

Anwendungsinformationen

Applikationshinweise: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Kommentare:

F8 Blocking Peptide, (ABIN938955), is also available for use as a blocking control in assays to test for specificity of this F8 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu Factor VIII

Target: Factor VIII (F8) (Coagulation Factor VIII (F8))

Andere Bezeichnung: F8

Hintergrund: This gene encodes coagulation factor VIII, which participates in the intrinsic pathway of blood coagulation, factor VIII is a cofactor for factor IXa which, in the presence of Ca+2 and phospholipids, converts factor X to the activated form Xa. This gene produces two alternatively spliced transcripts. Transcript variant 1 encodes a large glycoprotein, isoform a, which circulates in plasma and associates with von Willebrand factor in a noncovalent complex. This protein undergoes multiple cleavage events. Transcript variant 2 encodes a putative small protein, isoform b, which consists primarily of the phospholipid binding domain of factor VIIIc. This binding domain is essential for coagulant activity. Defects in this gene results in hemophilia A, a common recessive X-linked coagulation disorder. Synonyms: Polyclonal F8 antibody, Anti-F8 antibody, coagulation factor VIII, procoagulant component antibody, AHF antibody, DXS1253E antibody, F8B antibody, F8C antibody, FVIII antibody, HEMA antibody.