PDX1 Antikörper (N-Term)

Produktnummer ABIN927350

Der Kaninchen Polyklonal anti-PDX1 Antikörper wird verwendet zum Nachweis von PDX1 in Proben von Human und Maus. Er wurde validiert für WB.

Kurzübersicht für PDX1 Antikörper (N-Term) (ABIN927350)

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PDX1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PDX1 Antikörper

Bindungsspezifität: N-Term

Kreuzreaktivität: Maus

Aufreinigung: Purified

Immunogen: PDX1 antibody was raised in rabbit using the N terminal of Pdx1 as the immunogen

Anwendungsinformationen

Applikationshinweise: Optimal conditions should be determined by the investigator.

Kommentare:

PDX1 Blocking Peptide, (ABIN5615297), is also available for use as a blocking control in assays to test for specificity of this PDX1 antibody

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Lyophilized

Konzentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handhabung: Avoid repeated freeze/thaw cycles.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Details zu PDX1

Target: PDX1 (Pancreatic and Duodenal Homeobox 1 (PDX1))

Andere Bezeichnung: PDX1

Hintergrund: Pdx1 activates insulin and somatostatin gene transcription. It is a key regulator of islet peptide hormone expression but also responsible for the development of the pancreas, most probably by determining maturation and differentiation of common pancreatic precursor cells in the developing gut. It binds the DNA sequence 5'-CC[CT]TAATGGG-3'. Synonyms: Polyclonal Pdx1 antibody, Anti-Pdx1 antibody, pancreatic and duodenal homeobox 1 antibody, IDX-1 antibody, IPF-1 antibody, Ipf1 antibody, Mody4 antibody, STF-1 antibody, pdx-1 antibody.

Pathways: Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Hormone Transport, Carbohydrate Homeostasis, Chromatin Binding, Maintenance of Protein Location