PLEKHM3 Antikörper (AA 651-761) (Cy7)

Produktnummer ABIN911427

Der Cy7-konjugierte Kaninchen Polyklonal anti-PLEKHM3 Antikörper (ABIN911427) detektiert spezifisch PLEKHM3 in WB, IF (cc) und IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für PLEKHM3 Antikörper (AA 651-761) (Cy7) (ABIN911427)

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PLEKHM3 Antikörper ist konjugiert mit Cy7

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-PLEKHM3 Antikörper (Cy7)

Bindungsspezifität: AA 651-761

Homologie: Human,Mouse,Rat,Dog,Horse,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PLEKHM3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu PLEKHM3

Target: PLEKHM3 (Pleckstrin Homology Domain Containing, Family M, Member 3 (PLEKHM3))

Andere Bezeichnung: PLEKHM3

Hintergrund:

Synonyms: DAPR, PH domain containing family M member 3, PH domain-containing family M member 3, PKHM3_HUMAN, Pleckstrin homology domain containing family M member 3, Pleckstrin homology domain-containing family M member 3, PLEKHM1L, Plekhm3.

Background: PLEKHM3 (pleckstrin homology domain containing, family M, member 3), also known as DAPR or PLEKHM1L (pleckstrin homology domain containing, family M, member 1-like), is a 761 amino acid phosphoprotein that contains two pleckstrin homology (PH) domains and one phorbol-ester/DAG-type zinc finger. Conserved in chimpanzee, dog, cow, mouse, rat, chicken and zebrafish, PLEKHM3 exists as three alternatively spliced isoforms that participate in metal ion binding. The gene that encodes PLEKHM3 maps to human chromosome 2q33.3. As the second largest human chromosome, chromosome 2 makes up approximately 8 % of the human genome and contains 237 million bases encoding over 1,400 genes. Chromosome 2 contains a probable vestigial second centromere, as well as vestigial telomeres, which gives credence to the hypothesis that human chromosome 2 formed as a result of an ancient fusion of two ancestral chromosomes, which are still present in modern day apes.