PHLDA2 Antikörper (AA 31-80)

Produktnummer ABIN872459

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-PHLDA2 Antikörper wird verwendet zum Nachweis von PHLDA2 in Proben von Human und Ratte. Er wurde validiert für WB, ELISA, IF (cc), IF (p), IHC (p) und IHC (fro).

Kurzübersicht für PHLDA2 Antikörper (AA 31-80) (ABIN872459)

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Reaktivität: Human, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLDA2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-PHLDA2 Antikörper

Bindungsspezifität: AA 31-80

Kreuzreaktivität: Human, Ratte

Homologie: Mouse,Cow,Pig,Horse,Chicken

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human TSSC3

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-PHLDA2 Antikörper (ABIN872459)

Jin, Qiao, Luan, Li: "Lentivirus-mediated PHLDA2 overexpression inhibits trophoblast proliferation, migration and invasion, and induces apoptosis." in: International journal of molecular medicine, Vol. 37, Issue 4, pp. 949-57, (2016) (PubMed).

Jin, Qiao, Luan, Shang et al.: "The expression of the imprinted gene pleckstrin homology-like domain family A member 2 in placental tissues of preeclampsia and its effects on the proliferation, migration and invasion of trophoblast ..." in: Clinical and experimental pharmacology & physiology, Vol. 42, Issue 11, pp. 1142-51, (2015) (PubMed).

Details zu PHLDA2

Target: PHLDA2 (Pleckstrin Homology-Like Domain, Family A, Member 2 (PHLDA2))

Andere Bezeichnung: TSSC3

Hintergrund:

Synonyms: IPL, BRW1C, BWR1C, HLDA2, TSSC3, Pleckstrin homology-like domain family A member 2, Beckwith-Wiedemann syndrome chromosomal region 1 candidate gene C protein, Imprinted in placenta and liver protein, Tumor-suppressing STF cDNA 3 protein, Tumor-suppressing subchromosomal transferable fragment candidate gene 3 protein, p17-Beckwith-Wiedemann region 1 C, p17-BWR1C, PHLDA2

Background: Plays a role in regulating placenta growth. May act via its PH domain that competes with other PH domain-containing proteins, thereby preventing their binding to membrane lipids (By similarity).

Gen-ID: 7262

UniProt: Q53GA4

Pathways: Regulation of Carbohydrate Metabolic Process