Estrogen Receptor alpha Antikörper (C-Term)
Kurzübersicht für Estrogen Receptor alpha Antikörper (C-Term) (ABIN870443)
Target
Alle Estrogen Receptor alpha (ESR1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Bindungsspezifität
- AA 580-594, C-Term
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Verwendungszweck
- Anti-ER (Estrogen Receptor)
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Spezifität
- ER (Estrogen Receptor)
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Immunogen
- Peptide derived from C-terminal sequence of human estrogen receptor alpha. Antibody recognizes the epitope between Gln580 - Thr594.
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Isotyp
- IgG
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Applikationshinweise
- 1:100 - 200
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Buffer
- 20 mM Tris-HCI, pH 8.0, Stabilizer: 20 mg/mL BSA, Preservative: 0.05 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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Informationen zur Lagerung
- +2 °C to +8 °C
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- Estrogen Receptor alpha (ESR1) (Estrogen Receptor 1 (ESR1))
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Andere Bezeichnung
- Estrogen Receptor
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Hintergrund
- Estrogen Receptor- α antibody stains nuclei of breast epithelial cells and some carcinomas, as well as endometrial epithelia and myometrium. By binding to the DNA, estrogen receptor-α regulates positively or negatively the gene expression. ER plays an important role in regulation of mammary gland growth and differentiation. Its overexpression can be found in more than 70 % of breast cancer.
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UniProt
- P03372
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Pathways
- Nuclear Receptor Transcription Pathway, EGFR Signaling Pathway, Retinoic Acid Receptor Signaling Pathway, Intracellular Steroid Hormone Receptor Signaling Pathway, Steroid Hormone Mediated Signaling Pathway, Ribonucleoprotein Complex Subunit Organization, Ribosome Assembly
Target
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