NAC1 Antikörper
Kurzübersicht für NAC1 Antikörper (ABIN865493)
Target
Alle NAC1 (NACC1) Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
Klon
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Aufreinigung
- Ascitic fluid
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Immunogen
- Purified recombinant fragment of human NACC1 expressed in E. Coli.
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Isotyp
- IgG1
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anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (C-Term) antibody
NACC1 Reaktivität: Human, Affe WB, IHC, IHC (p) Wirt: Kaninchen Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (AA 324-358) antibodyNACC1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal RB51582 unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) antibodyNACC1 Reaktivität: Human ELISA, IHC Wirt: Maus Monoclonal 6H2 unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (C-Term) antibodyNACC1 Reaktivität: Human, Ratte, Maus, Hund, Rind (Kuh), Meerschweinchen, Pferd, Schwein WB, IHC Wirt: Kaninchen Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) antibodyNACC1 Reaktivität: Human, Maus WB Wirt: Kaninchen Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (AA 355-390), (C-Term) antibodyNACC1 Reaktivität: Maus WB Wirt: Kaninchen Polyclonal RB51581 unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (Internal Region) antibodyVerified NACC1 Reaktivität: Human WB, ELISA Wirt: Ziege Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (Internal Region) antibodyNACC1 Reaktivität: Human, Ratte, Maus WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) antibodyNACC1 Reaktivität: Human WB, ELISA Wirt: Kaninchen Polyclonal unconjugated
anti-Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1) (AA 170-340) antibodyNACC1 Reaktivität: Human WB, IHC Wirt: Kaninchen Polyclonal unconjugated
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Applikationshinweise
- WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, ELISA: Propose dilution 1/10000.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 100g/100l
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Lagerung
- 4 °C
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- NAC1 (NACC1) (Nucleus Accumbens Associated 1, BEN and BTB (POZ) Domain Containing (NACC1))
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Andere Bezeichnung
- NAC1
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Hintergrund
- NAC1 or nuclear accumbens-1 is a nuclear factor that belongs to the POZ/BTB (Pox virus and zinc finger/bric-a-brac tramtrack broad complex) domain family. Also known as BTBD14B, it was originally identified in a unique neuronal forebrain structure responsible for reward motivation and addictive behaviors . NAC1 recruits HDAC3 and HDAC4 to transcriptionally repress gene expression in neuronal cells (3) and specifically co-represses other POZ/BTB proteins in the central nervous system . NAC1 is upregulated in several tumor types, including breast, renal cell, and hepatocellular carcinoma, as well as high grade ovarian serous carcinoma, where it has long been suspected as a chemoresistance gene . The chemoresistance mechanism reportedly occurs through NAC1 negative regulation of the GADD45 pathway . NAC1 has also been described as part of the extended transcriptional network in pluripotent cells that involves Oct-4, Sox2, Nanog, Sall1, KLF4 and Sall4 . Tissue specificity: Synonyms: NAC1, BEND8, NAC-1, BTBD14B, FLJ37383, NACC1
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Molekulargewicht
- 58kDa
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Gen-ID
- 112939
Target
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