ATP6V1F Antikörper

Produktnummer ABIN2716463

Dieser Maus Monoklonal Antikörper detektiert spezifisch ATP6V1F in WB, IHC, FACS und IF. Es zeigt Reaktivität gegenüber Proben von Human.

Kurzübersicht für ATP6V1F Antikörper (ABIN2716463)

Target: ATP6V1F (ATPase, H+ Transporting, Lysosomal 14kDa, V1 Subunit F (ATP6V1F))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser ATP6V1F Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 1B8

Produktdetails anti-ATP6V1F Antikörper

Produktmerkmale: Homo sapiens ATPase, H+ transporting, lysosomal 14 kDa, V1 subunit F (ATP6V1F), transcript variant 1

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human ATP6V1F (NP_004222) produced in E.coli.

Isotyp: IgG2a

Anwendungsinformationen

Applikationshinweise: WB 1:2000, IHC 1:150, IF 1:100, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu ATP6V1F

Target: ATP6V1F (ATPase, H+ Transporting, Lysosomal 14kDa, V1 Subunit F (ATP6V1F))

Andere Bezeichnung: ATP6V1F

Hintergrund: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is the V1 domain F subunit protein.

Molekulargewicht: 13.2 kDa

Gen-ID: 9296

NCBI Accession: NM_004231

HGNC: 9296

Pathways: Transition Metal Ion Homeostasis, Proton Transport