LOX Antikörper (AA 22-168)

Produktnummer ABIN2725060

Der Maus Monoklonal anti-LOX Antikörper wird verwendet zum Nachweis von LOX in Proben von Human. Er wurde validiert für WB, IHC, FACS und IF.

Kurzübersicht für LOX Antikörper (AA 22-168) (ABIN2725060)

Target: LOX (Lysyl Oxidase (LOX))

Reaktivität: Human

Wirt: Maus

Klonalität: Monoklonal

Konjugat: Dieser LOX Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS), Immunofluorescence (IF)

Klon: 9G2

Produktdetails anti-LOX Antikörper

Bindungsspezifität: AA 22-168

Produktmerkmale: Homo sapiens lysyl oxidase (LOX), transcript variant 1

Aufreinigung: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Human recombinant protein fragment corresponding to amino acids 22-168 of human LOX (NP_002308) produced in HEK293T cell.

Isotyp: IgG1

Anwendungsinformationen

Applikationshinweise: WB 1:500, IHC 1:150, IF 1:100, FLOW 1:100,

Kommentare:

The concentration of the product may vary between diferrent lots.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 0.5-1.0 mg/mL

Buffer: PBS ( pH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: -20 °C

Details zu LOX

Target: LOX (Lysyl Oxidase (LOX))

Andere Bezeichnung: LOX

Hintergrund: The protein encoded by this gene is an extracellular copper enzyme that initiates the crosslinking of collagens and elastin. The enzyme catalyzes oxidative deamination of the epsilon-amino group in certain lysine and hydroxylysine residues of collagens and lysine residues of elastin. In addition to crosslinking extracellular matrix proteins, the encoded protein may have a role in tumor suppression. Defects in this gene are a cause of autosomal recessive cutis laxa type I (CL type I). Two transcript variants encoding different isoforms have been found for this gene.

Molekulargewicht: 46.8 kDa

Gen-ID: 4015

NCBI Accession: NM_002317

HGNC: 4015

Pathways: SARS-CoV-2 Protein Interaktom