HMGN1 Antikörper (pSer21, pSer25) (Cy3)

Produktnummer ABIN801276

Der Cy3-konjugierte Kaninchen Polyklonal anti-HMGN1 Antikörper (ABIN801276) detektiert spezifisch HMGN1 in WB, IF (p) und IF (cc). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für HMGN1 Antikörper (pSer21, pSer25) (Cy3) (ABIN801276)

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HMGN1 Antikörper ist konjugiert mit Cy3

Applikation: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Produktdetails anti-HMGN1 Antikörper (Cy3)

Bindungsspezifität: pSer21, pSer25

Homologie: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HMGN1 around the phosphorylation site of Ser20+Ser24

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HMGN1

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Andere Bezeichnung: HMGN1+

Hintergrund:

Synonyms: HMG14 phospho S21 + S25, High mobility group nonhistone chromosomal protein 14, High mobility group nucleosome binding 1, High mobility group nucleosome binding domain containing protein 1, High mobility group protein 14, High-mobility group nucleosome binding domain 1, HMG14, HMGN 1, HMGN1, MGC104230, MGC117425, Nonhistone chromosomal protein HMG-14, Nonhistone chromosomal protein HMG14, FLJ27265, FLJ31471.

Background: Chromosomal protein HMG14 binds to the inner side of the nucleosomal DNA, thus altering the interaction between the DNA and the histone octamer and is involved in the process that maintains transcribable genes in an appropriate chromatin conformation. HMG14 has been implicated as a contributing factor in the etiology of Down syndrome.

Gen-ID: 3150

Pathways: Chromatin Binding