EIF2B5 Antikörper (N-Term)

Produktnummer ABIN786396

Zitiert in 1 Publikation. Der Kaninchen Polyklonal anti-EIF2B5 Antikörper (ABIN786396) detektiert spezifisch EIF2B5 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Rind (Kuh), Pferd und Hund.

Kurzübersicht für EIF2B5 Antikörper (N-Term) (ABIN786396)

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Reaktivität: Human, Ratte, Rind (Kuh), Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser EIF2B5 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-EIF2B5 Antikörper

Bindungsspezifität: N-Term

Sequenz: GVVVSRANKR SGAGPGGSGG GGARGAEEEP PPPLQAVLVA DSFDRRFFPI

Homologie: Cow: 85%, Dog: 92%, Horse: 85%, Human: 100%, Rat: 85%

Produktmerkmale: This is a rabbit polyclonal antibody against EIF2B5. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 721 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-EIF2B5 Antikörper (ABIN786396)

Wortham, Stewart, Harris, Coldwell, Proud: "Stoichiometry of the eIF2B complex is maintained by mutual stabilization of subunits." in: The Biochemical journal, Vol. 473, Issue 5, pp. 571-80, (2016) (PubMed).

Details zu EIF2B5

Target: EIF2B5 (Eukaryotic Translation Initiation Factor 2B, Subunit 5 Epsilon, 82kDa (EIF2B5))

Andere Bezeichnung: EIF2B5

Hintergrund: This gene encodes one of five subunits of eukaryotic translation initiation factor 2B (EIF2B), a GTP exchange factor for eukaryotic initiation factor 2 and an essential regulator for protein synthesis. Mutations in this gene and the genes encoding other EIF2B subunits have been associated with leukoencephalopathy with vanishing white matter.
Alias Symbols: CACH, CLE, EIF-2B, EIF2Bepsilon, LVWM
Protein Interaction Partner: UBC, EGFR, EIF2B2, EIF2B3, EIF2B4, APP, CHMP2A, GSK3A, GSK3B, EIF2S2, CSNK1A1, CSNK2A2, CSNK2A1, EIF2B1,
Protein Size: 721

Molekulargewicht: 79 kDa

Gen-ID: 8893

NCBI Accession: NM_003907, NP_003898

UniProt: Q13144