UGDH Antikörper (C-Term)

Produktnummer ABIN786373

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch UGDH in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund und Meerschweinchen.

Kurzübersicht für UGDH Antikörper (C-Term) (ABIN786373)

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Pferd, Kaninchen, Hund, Meerschweinchen

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser UGDH Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-UGDH Antikörper

Bindungsspezifität: C-Term

Sequenz: VLDGLHNELQ TIGFQIETIG KKVSSKRIPY APSGEIPKFS LQDPPNKKPK

Homologie: Cow: 92%, Dog: 100%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against UGDH. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 494 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu UGDH

Target: UGDH (UDP-Glucose 6-Dehydrogenase (UGDH))

Andere Bezeichnung: UGDH

Hintergrund: The protein encoded by this gene converts UDP-glucose to UDP-glucuronate and thereby participates in the biosynthesis of glycosaminoglycans such as hyaluronan, chondroitin sulfate, and heparan sulfate. These glycosylated compounds are common components of the extracellular matrix and likely play roles in signal transduction, cell migration, and cancer growth and metastasis. The expression of this gene is up-regulated by transforming growth factor beta and down-regulated by hypoxia.
Alias Symbols: GDH, UDP-GlcDH, UDPGDH, UGD
Protein Interaction Partner: UGDH, CIAO1, SUMO2, UBC, XPO5, MAT2B, RPUSD2, GORASP2, BOP1, RNASEH2A, ATG7, PDIA6, SNX1, PRKACA, ME1, MAT2A, GTF2A1, GARS, CTTN, BAG3, UGT1A1, RAD51, UBE2V1, TKT, ELAVL1, SIRT1, SIRT3, TERF2, AK5,
Protein Size: 494

Molekulargewicht: 54 kDa

Gen-ID: 7358

NCBI Accession: NM_003359, NP_003350

UniProt: O60701

Pathways: Glycosaminoglycan Metabolic Process