H2AFY2 Antikörper (Middle Region)

Produktnummer ABIN785880

Der Kaninchen Polyklonal anti-H2AFY2 Antikörper (ABIN785880) detektiert spezifisch H2AFY2 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Meerschweinchen, Kaninchen, Pferd, Rind (Kuh) und Hund.

Kurzübersicht für H2AFY2 Antikörper (Middle Region) (ABIN785880)

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Reaktivität: Human, Maus, Ratte, Meerschweinchen, Kaninchen, Pferd, Rind (Kuh), Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser H2AFY2 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-H2AFY2 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PRIHPELLAK KRGTKGKSET ILSPPPEKRG RKATSGKKGG KKSKAAKPRT

Homologie: Cow: 93%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against H2AFY2. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human H2AFY2

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 372 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu H2AFY2

Target: H2AFY2 (H2A Histone Family, Member Y2 (H2AFY2))

Andere Bezeichnung: H2AFY2

Hintergrund: H2AFY2 is the variant histone H2A which replaces conventional H2A in a subset of nucleosomes where it represses transcription. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. H2AFY2 may be involved in stable X chromosome inactivation.
Alias Symbols: macroH2A2
Protein Interaction Partner: UBC, SUZ12, EED, WWP1, CBX5, DIDO1, SUMO1, HDGF, tat,
Protein Size: 372

Molekulargewicht: 40 kDa

Gen-ID: 55506

NCBI Accession: NM_018649, NP_061119

UniProt: Q9P0M6