FBXW8 Antikörper (Middle Region)

Produktnummer ABIN785757

Der Kaninchen Polyklonal anti-FBXW8 Antikörper (ABIN785757) detektiert spezifisch FBXW8 in WB. Dieser Antikörper reagiert spezifisch mit Proben aus Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd und Hund.

Kurzübersicht für FBXW8 Antikörper (Middle Region) (ABIN785757)

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Reaktivität: Human, Ratte, Maus, Rind (Kuh), Kaninchen, Meerschweinchen, Pferd, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser FBXW8 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-FBXW8 Antikörper

Bindungsspezifität: Middle Region

Sequenz: RNADLDSFTT HRRHRGLIRA YEFAVDQLAF QSPLPVCRSS CDAMATHYYD

Homologie: Cow: 86%, Dog: 92%, Guinea Pig: 93%, Horse: 86%, Human: 100%, Mouse: 93%, Rabbit: 86%, Rat: 93%

Produktmerkmale: This is a rabbit polyclonal antibody against FBXW8. It was validated on Western Blot.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FBXW8

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 598 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Details zu FBXW8

Target: FBXW8 (F-Box and WD Repeat Domain Containing 8 (FBXW8))

Andere Bezeichnung: FBXW8

Hintergrund: FBXW8 is a member of the F-box protein family, members of which are characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into three classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXW8 contains a WD-40 domain, in addition to an F-box motif, so it belongs to the Fbw class.
Alias Symbols: FBW6, FBW8, FBX29, FBXO29, MGC33534, FBXW6
Protein Interaction Partner: MAP4K1, CUL1, TBC1D3, CUL7, UBE2D3, SKP1, IRS1, REST, CCND1, CUL4A, DDB1, UBC, CCDC8, GORASP1, OBSL1, CCT6B, CCT2, CCT7, TRIP13, PDCD5, CUL2, VBP1, CCT3, PFDN5, NFKBIA, CCT6A, BCL3, BTRC, SKP2, HSP90AA1, HSPA4, FBXO4, FBXW8, FBXW2, MYC, RBX1, UBI4, EP300,
Protein Size: 598

Molekulargewicht: 67 kDa

Gen-ID: 26259

NCBI Accession: NM_153348, NP_699179

UniProt: Q8N3Y1