PHLDA1 Antikörper (Middle Region)

Produktnummer ABIN785710

Dieser Kaninchen Polyklonal Antikörper detektiert spezifisch PHLDA1 in WB. Es zeigt Reaktivität gegenüber Proben von Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen und Hund.Es wurde in 1 Publikation zitiert.

Kurzübersicht für PHLDA1 Antikörper (Middle Region) (ABIN785710)

Target: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Meerschweinchen, Pferd, Kaninchen, Hund

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PHLDA1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB)

Produktdetails anti-PHLDA1 Antikörper

Bindungsspezifität: Middle Region

Sequenz: PAVASLEPPV KLKELHFSNM KTVDCVERKG KYMYFTVVMA EGKEIDFRCP

Homologie: Cow: 100%, Dog: 93%, Guinea Pig: 100%, Horse: 100%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%

Produktmerkmale: This is a rabbit polyclonal antibody against PHLDA1. It was validated on Western Blot using a cell lysate as a positive control.

Aufreinigung: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human PHLDA1

Anwendungsinformationen

Applikationshinweise: Optimal working dilutions should be determined experimentally by the investigator.

Kommentare:

Antigen size: 401 AA

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freeze-thaw cycles.

Lagerung: -20 °C

Informationen zur Lagerung: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Referenzen für anti-PHLDA1 Antikörper (ABIN785710)

Tsuda, Davis, Argani, Shukla, McGill, Nagai, Saito, Laé, Fisher, Ladanyi: "TFE3 fusions activate MET signaling by transcriptional up-regulation, defining another class of tumors as candidates for therapeutic MET inhibition." in: Cancer research, Vol. 67, Issue 3, pp. 919-29, (2007) (PubMed).

Details zu PHLDA1

Target: PHLDA1 (Pleckstrin Homology-Like Domain, Family A, Member 1 (PHLDA1))

Andere Bezeichnung: PHLDA1

Hintergrund: PHLDA1 is an evolutionarily conserved proline-histidine rich nuclear protein. It may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.This gene encodes an evolutionarily conserved proline-histidine rich nuclear protein. The encoded protein may play an important role in the anti-apoptotic effects of insulin-like growth factor-1.
Alias Symbols: DT1P1B11, MGC131738, PHRIP, TDAG51
Protein Interaction Partner: UBC, SUMO1, MDFI, EGFR, APP, DNAJB1, HSPB1, HSPA4, ELAVL1, KRTAP4-12, RPL14, PLSCR1, HSPA4L, EIF3D, PABPC4,
Protein Size: 401

Molekulargewicht: 45 kDa

Gen-ID: 22822

NCBI Accession: NM_007350, NP_031376

UniProt: Q8WV24