SLC25A19 Antikörper (Middle Region)
Kurzübersicht für SLC25A19 Antikörper (Middle Region) (ABIN785247)
Target
Alle SLC25A19 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- VHRGSVYDAR EFSVHFVCGG LAACMATLTV HPVDVLRTRF AAQGEPKVYN
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Homologie
- Cow: 93%, Dog: 93%, Guinea Pig: 93%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 100%, Rat: 100%, Sheep: 93%, Yeast: 77%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SLC25A19. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SLC25A19
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 320 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLC25A19 (Solute Carrier Family 25 (Mitochondrial Thiamine Pyrophosphate Carrier), Member 19 (SLC25A19))
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Andere Bezeichnung
- SLC25A19
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Hintergrund
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This gene encodes a mitochondrial protein that is a member of the solute carrier family. Although this protein was initially thought to be the mitochondrial deoxynucleotide carrier involved in the uptake of deoxynucleotides into the matrix of the mitochondria, further studies have demonstrated that this protein instead functions as the mitochondrial thiamine pyrophosphate carrier, which transports thiamine pyrophosphates into mitochondria. Mutations in this gene cause microcephaly, Amish type, a metabolic disease that results in severe congenital microcephaly, severe 2-ketoglutaric aciduria, and death within the first year. Multiple alternatively spliced variants, encoding the same protein, have been identified for this gene.
Alias Symbols: DNC, MCPHA, MUP1, TPC, THMD3, THMD4
Protein Interaction Partner: UBC,
Protein Size: 320 -
Molekulargewicht
- 35 kDa
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Gen-ID
- 60386
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NCBI Accession
- NM_021734, NP_068380
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UniProt
- Q9HC21
Target
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