SLCO1B1 Antikörper (Middle Region)
Kurzübersicht für SLCO1B1 Antikörper (Middle Region) (ABIN785242)
Target
Alle SLCO1B1 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- Middle Region
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Sequenz
- IILIYAMKKK YQEKDINASE NGSVMDEANL ESLNKNKHFV PSAGADSETH
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Homologie
- Cow: 86%, Human: 100%, Pig: 79%
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Produktmerkmale
- This is a rabbit polyclonal antibody against SLCO1B1. It was validated on Western Blot.
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Aufreinigung
- Affinity Purified
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Immunogen
- The immunogen is a synthetic peptide directed towards the middle region of human SLCO1B1
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Applikationshinweise
- Optimal working dilutions should be determined experimentally by the investigator.
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Kommentare
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Antigen size: 691 AA
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- Lot specific
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Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freeze-thaw cycles.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- SLCO1B1 (Solute Carrier Organic Anion Transporter Family, Member 1B1 (SLCO1B1))
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Andere Bezeichnung
- SLCO1B1
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Hintergrund
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This gene encodes a liver-specific member of the organic anion transporter family. The encoded protein is a transmembrane receptor that mediates the sodium-independent uptake of numerous endogenous compounds including bilirubin, 17-beta-glucuronosyl estradiol and leukotriene C4. This protein is also involved in the removal of drug compounds such as statins, bromosulfophthalein and rifampin from the blood into the hepatocytes. Polymorphisms in the gene encoding this protein are associated with impaired transporter function.
Alias Symbols: LST-1, MGC133282, OATP-C, OATP1B1, OATP2, SLC21A6, LST1, HBLRR, OATPC
Protein Size: 691 -
Molekulargewicht
- 76 kDa
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Gen-ID
- 10599
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NCBI Accession
- NM_006446, NP_006437
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UniProt
- Q9Y6L6
Target
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