SLC39A12 Antikörper (N-Term)

Produktnummer ABIN783813

Der Kaninchen Polyklonal anti-SLC39A12 Antikörper (ABIN783813) detektiert spezifisch SLC39A12 in WB und EIA. Dieser Antikörper reagiert spezifisch mit Proben aus Human und Maus.

Kurzübersicht für SLC39A12 Antikörper (N-Term) (ABIN783813)

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SLC39A12 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-SLC39A12 Antikörper

Bindungsspezifität: N-Term

Spezifität: This antibody detects Zinc transporter ZIP12 / SLC39A12 at N-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 15 amino acid peptide near the amino terminus of human ZIP12

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu SLC39A12

Target: SLC39A12 (Solute Carrier Family 39 (Zinc Transporter), Member 12 (SLC39A12))

Andere Bezeichnung: Zinc Transporter ZIP12 / SLC39A12

Hintergrund: The zinc transporter ZIP12, also known as SLC39A12, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. The zinc transporter family is divided into four subfamilies (I, II, LIV-1 and gufA). ZIP12 is a multipass membrane protein that belongs to the ZIP transporter subfamily LIV-1. Increased levels of ZIP12 have been observed during acute inflammation in the airway and asthma, suggesting that it may be promote increased zinc uptake, as this can reduce inflammation. The zinc content in brains in individuals with schizophrenia is lower than in individuals with other cerebral diseases, and mutations in ZIP12 have been observed in a small group of schizophrenic patients, suggesting that ZIP12 may play a role in this disease.Synonyms: LIV-1 subfamily of ZIP zinc transporter 8, LZT-Hs8, Solute carrier family 39 member 12, ZIP-12, ZIP12, Zrt-and Irt-like protein 12

Gen-ID: 221074

NCBI Accession: NP_001138667

UniProt: Q504Y0