SLC39A7 Antikörper (N-Term)
Kurzübersicht für SLC39A7 Antikörper (N-Term) (ABIN783807)
Target
Alle SLC39A7 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- N-Term
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Spezifität
- This antibody detects SLC39A7 at N-term.
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Kreuzreaktivität (Details)
- Species reactivity (tested):Human, mouse, rat
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Aufreinigung
- Affinity chromatography purified via peptide column
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Immunogen
- 17 amino acid peptide near the amino terminus of human ZIP7
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Applikationshinweise
- Optimal working dilution should be determined by the investigator.
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Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Buffer
- PBS containing 0.02 % sodium azide
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Konservierungsmittel
- Sodium azide
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Vorsichtsmaßnahmen
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Handhabung
- Avoid repeated freezing and thawing.
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Lagerung
- 4 °C/-20 °C
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Informationen zur Lagerung
- Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
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- SLC39A7 (Solute Carrier Family 39 (Zinc Transporter), Member 7 (SLC39A7))
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Andere Bezeichnung
- SLC39A7
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Hintergrund
- The zinc transporter ZIP7, also known as SLC39A7, is a member of a family of divalent ion transporters. Zinc is an essential ion for cells and plays significant roles in the growth, development, and differentiation. ZIP7 was initially identified while characterizing genes in the major histocompatibility complex on chromosome 17. ZIP7 mRNA is abundantly and widely expressed and the protein localizes to the Golgi apparatus. It functions to transport intracellular zinc from the Golgi apparatus to the cytoplasm of the cell. ZIP7 expression is expressed by zinc. ZIP7 has been suggested to act a hub for tyrosine kinase activation and may thus be a potential therapeutic target for diseases such as cancer where prevention of tyrosine kinase activation would be advantageous.Synonyms: HKE4, Histidine-rich membrane protein Ke4, RING5, Really interesting new gene 5 protein, Solute carrier family 39 member 7, Zinc transporter SLC39A7
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Gen-ID
- 7922
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NCBI Accession
- NP_001070984
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UniProt
- Q92504
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Pathways
- Transition Metal Ion Homeostasis
Target
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