PEAR1 Antikörper (C-Term)

Produktnummer ABIN783779

Der Kaninchen Polyklonal anti-PEAR1 Antikörper wird verwendet zum Nachweis von PEAR1 in Proben von Human, Maus und Ratte. Er wurde validiert für WB und EIA.

Kurzübersicht für PEAR1 Antikörper (C-Term) (ABIN783779)

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser PEAR1 Antikörper ist unkonjugiert

Applikation: Western Blotting (WB), Enzyme Immunoassay (EIA)

Produktdetails anti-PEAR1 Antikörper

Bindungsspezifität: C-Term

Spezifität: This antibody detects PEAR1 at C-term.

Kreuzreaktivität (Details): Species reactivity (tested):Human, mouse, rat

Aufreinigung: Affinity chromatography purified via peptide column

Immunogen: 16 amino acid peptide near the carboxy terminus of human PEAR1

Anwendungsinformationen

Applikationshinweise: Optimal working dilution should be determined by the investigator.

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Buffer: PBS containing 0.02 % sodium azide

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handhabung: Avoid repeated freezing and thawing.

Lagerung: 4 °C/-20 °C

Informationen zur Lagerung: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Details zu PEAR1

Target: PEAR1 (Platelet Endothelial Aggregation Receptor 1 (PEAR1))

Andere Bezeichnung: PEAR1

Hintergrund: Platelet endothelial aggregation receptor 1 (PEAR1) is a platelet receptor that signals upon the formation of platelet-platelet contacts independent of platelet activation and secondary to platelet aggregation. Upon platelet aggregation stimulated by physiological agonists, PEAR1 becomes tyrosine- and serine-phosphorylated, the tyrosine phosphorylation can be inhibited by eptifibatide, an aIIbb3 antagonist that also inhibits platelet aggregation. Recent studies have indicated that genetic variations in PEAR1, may be associated with enhanced agonist-induced platelet aggregation.Synonyms: MEGF12, Multiple EGF-like domains protein 12, Multiple epidermal growth factor-like domains protein 12, Platelet endothelial aggregation receptor 1

Gen-ID: 375033

NCBI Accession: NP_001073940

UniProt: Q5VY43