ADAM Metallopeptidase Domain 19 (Adam19) Antikörper

Antigen: ADAM Metallopeptidase Domain 19 (Adam19)

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), ELISA, Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)), Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN758801

Produktbeschreibung

Weitere Bezeichnung: ADAM19

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human ADAM19

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Synonym: Meltrin beta, Metalloprotease and disintegrin dentritic antigen marker, A disintegrin and metalloproteinase domain 19 (meltrin beta), A disintegrin and metalloproteinase domain 19, ADAM 19, ADAM-19, ADAM metallopeptidase domain 19, Disintegrin and metalloproteinase domain containing protein 19, FKSG 34, FKSG34, MADDAM, MLTN B, MLTNB.

Molekulargewicht: 82kDa

Kommentare:

ADAM19

is a member of the ADAM (a disintegrin and metalloprotease-like domain) family. It has been cloned from mouse and human. ADAM19 was first described in muscle cells as a protein with homology to the fertilins (ADAMs 1 and 2). Initial observations indicated a role for ADAM19 in myoblast fusion

similar to sperm-egg fusion aided by ADAMs 1 and 2. Later works describe ADAM19 in the bone

muscle

lung

heart

brain

kidney

and a wide range of tissues. The Cytoplasmic domain of ADAM19

like ADAMs 9

12 and 15

contains SH3 ligand domains

which are thought to interact with PKC-d

suggesting specific regulation routes for ADAM19. Also reported is a sequence of ADAM19 lacking the transmembrane and cytoplasmic domains

suggesting that a soluble form is produced.

Anwendungen

Applikationshinweise: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: affinity purified by Protein A

Buffer: 0.01M PBS, pH 7.4 with 10 mg/ml BSA and 0.1% Sodium azide

Lagerung: Ship at room temperature. Store at -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar