CACNA1E Antikörper (PE)

Produktnummer ABIN751358

Der Kaninchen Polyklonal anti-CACNA1E Antikörper wird verwendet zum Nachweis von CACNA1E in Proben von Human, Maus und Ratte. Er wurde validiert für FACS.

Kurzübersicht für CACNA1E Antikörper (PE) (ABIN751358)

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser CACNA1E Antikörper ist konjugiert mit PE

Applikation: Flow Cytometry (FACS)

Produktdetails anti-CACNA1E Antikörper (PE)

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Cav23

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: FCM(1:20-100)

Kommentare:

Exitation/Emission: 480,565nm/578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at 4°C

Haltbarkeit: 12 months

Details zu CACNA1E

Target: CACNA1E (Calcium Channel, Voltage-Dependent, R Type, alpha 1E Subunit (CACNA1E))

Andere Bezeichnung: Cach6/Cav2.3

Hintergrund:

Calcium channels mediate the influx of calcium ions into the cell following membrane polarisation. R-type calcium channels such as Cav2.3 belong to the "high voltage-activated" group and are blocked by nickel. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. Each of these proteins exists as multiple isoforms, either encoded by different genes or arising from alternative splicing of transcripts. Cav2.3 is an alpha-1 subunit and has 24 transmembrane segments, which form the pore through which ions pass into the cell. Calcium channels containing the Cav2.3 subunit may be involved in the modulation of firing patterns of neurons, which is important for information processing.

Subcellular location: Extracellular

Synonyms: BII, Brain calcium channel II, CAC 1E, CAC1E, CACH 6, CACH6, CACNA1E, Cacnl1 a6, CACNL1A6, Calcium channel, L type, alpha 1 polypeptide, isoform 6, calcium channel, R type, Cav 2.3, Cchra 1, Cchra1, Voltage dependent R type calcium channel subunit alpha 1E, Voltage gated calcium channel subunit alpha Cav2.3.

Gen-ID: 777

Pathways: Carbohydrate Homeostasis