SEMA6A Antikörper (PE)

Produktnummer ABIN749358

Der PE-konjugierte Kaninchen Polyklonal anti-SEMA6A Antikörper (ABIN749358) detektiert spezifisch SEMA6A in IF (p). Dieser Antikörper reagiert spezifisch mit Proben aus Human, Maus, Ratte, Rind (Kuh), Hund und Schwein.

Kurzübersicht für SEMA6A Antikörper (PE) (ABIN749358)

Target: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Reaktivität: Human, Maus, Ratte, Rind (Kuh), Hund, Schwein

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser SEMA6A Antikörper ist konjugiert mit PE

Applikation: Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-SEMA6A Antikörper (PE)

Spezifität: Excitation / Emission Wavelengths: 565nm/578nm

Kreuzreaktivität: Ratte (Rattus), Hund, Schwein, Rind (Kuh)

Aufreinigung: purified by Protein A

Immunogen: KLH conjugated synthetic peptide derived from human Sema6A

Isotyp: IgG

Anwendungsinformationen

Kommentare:

Excitation / Emission wavelength: 496nm / 578nm

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 µg/µL

Buffer: Aqueous buffered solution containing 100 µg/mL BSA, 50 % glycerol and 0.09 % sodium azide.

Konservierungsmittel: Sodium azide

Vorsichtsmaßnahmen: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Lagerung: 4 °C

Informationen zur Lagerung: Store at 4 °C for 12 months

Haltbarkeit: 12 months

Details zu SEMA6A

Target: SEMA6A (Sema Domain, Transmembrane Domain (TM), and Cytoplasmic Domain, (Semaphorin) 6A (SEMA6A))

Andere Bezeichnung: Sema6A

Hintergrund: SEMA6A belongs to a subfamily characterized by an extracellular semaphorin domain, a transmembrane domain, and a long cytoplasmic tail. Members of this class can repel sympathetic and dorsal root ganglion axons in vitro, consistent with a traditional role as guidance signals. However, the length of the cytoplasmic tail, which includes an EVL-binding site in SEMA6A and an Src-binding site in SEMA6B, suggests that these semaphorins may also function as receptors. SEMA6A is expressed in developing neural tissue and is required for proper development of the thalamocortical projection. SEMA6A directly links the Ena/VASP and the semaphorin protein families since the SEMA6A protein is capable of selective binding to the protein EVL (Ena/VASP-like protein.

Molekulargewicht: 113kDa

Gen-ID: 57556