HSP90AA2 Antikörper (pThr5, pThr7) (HRP)

Produktnummer ABIN742487

Der Kaninchen Polyklonal anti-HSP90AA2 Antikörper wird verwendet zum Nachweis von HSP90AA2 in Proben von Human und Maus. Er wurde validiert für WB, ELISA, IHC (p) und IHC (fro).

Kurzübersicht für HSP90AA2 Antikörper (pThr5, pThr7) (HRP) (ABIN742487)

Target: HSP90AA2 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2))

Reaktivität: Human, Maus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser HSP90AA2 Antikörper ist konjugiert mit HRP

Applikation: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-HSP90AA2 Antikörper (HRP)

Bindungsspezifität: pThr5, pThr7

Spezifität: These phosphorylation sites are homologous across the listed species.

Kreuzreaktivität: Human, Maus

Homologie: Rat,Pig,Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HSP90 around the phosphorylation site of Thr5/7

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handhabung: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu HSP90AA2

Target: HSP90AA2 (Heat Shock Protein 90kDa alpha (Cytosolic), Class A Member 2 (HSP90AA2))

Andere Bezeichnung: HSP90 alpha +

Hintergrund:

Synonyms: EL52, HSPN, LAP2, HSP86, HSPC1, HSPCA, Hsp89, Hsp90, LAP-2, HSP89A, HSP90A, HSP90N, HSPCAL1, HSPCAL4, Heat shock protein HSP 90-alpha, Heat shock 86 kDa, HSP 86, Lipopolysaccharide-associated protein 2, LPS-associated protein 2, Renal carcinoma antigen NY-REN-38, HSP90AA1

Background: Molecular chaperone that promotes the maturation, structural maintenance and proper regulation of specific target proteins involved for instance in cell cycle control and signal transduction. Undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. Interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function. Binds bacterial lipopolysaccharide (LPS) et mediates LPS-induced inflammatory response, including TNF secretion by monocytes.

Gen-ID: 3320

UniProt: P07900