NR1I2 Antikörper (AA 101-150) (Cy5.5)

Produktnummer ABIN738821

Der Kaninchen Polyklonal anti-NR1I2 Antikörper wird verwendet zum Nachweis von NR1I2 in Proben von Human, Maus und Ratte. Er wurde validiert für WB, IF (cc) und IF (p).

Kurzübersicht für NR1I2 Antikörper (AA 101-150) (Cy5.5) (ABIN738821)

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Reaktivität: Human, Maus, Ratte

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser NR1I2 Antikörper ist konjugiert mit Cy5.5

Applikation: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Produktdetails anti-NR1I2 Antikörper (Cy5.5)

Bindungsspezifität: AA 101-150

Kreuzreaktivität: Human, Maus, Ratte

Homologie: Rabbit

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PAR2

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Haltbarkeit: 12 months

Details zu NR1I2

Target: NR1I2 (Nuclear Receptor Subfamily 1, Group I, Member 2 (NR1I2))

Andere Bezeichnung: PAR-2

Hintergrund:

Synonyms: PAR2, GPR11, Proteinase-activated receptor 2, PAR-2, Coagulation factor II receptor-like 1, G-protein coupled receptor 11, Thrombin receptor-like 1, F2RL1

Background: Coagulation factor II (thrombin) receptor-like 1 (F2RL1) is a member of the large family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins. F2RL1 is also a member of the protease-activated receptor family. It is activated by trypsin, but not by thrombin. It is activated by proteolytic cleavage of its extracellular amino terminus. The new amino terminus functions as a tethered ligand and activates the receptor. The F2RL1 gene contains two exons and is widely expressed in human tissues. The predicted protein sequence is 83 % identical to the mouse receptor sequence. [provided by RefSeq, Jul 2008]

Gen-ID: 2150

UniProt: P55085

Pathways: Nuclear Receptor Transcription Pathway, Steroid Hormone Mediated Signaling Pathway