M-Cadherin Antikörper

Antigen: M-Cadherin

Klonalität: Polyklonal

Wirt: Kaninchen

Reaktivität: Human, Maus, Ratte (Rattus)

Applikation: Western Blot (WB), ELISA, Immunpräzipitation (IP), Immunhistochemie (Paraffinschnitte) (IHC (p)), Immunhistochemie (formalinfixierte Schnitte) (IHC (f)), Durchflusszytometrie (FACS), Immunfluoreszenz (IF)

Produktnummer: ABIN719831

Produktbeschreibung

Immunogen: Polyclonal antibodies are produced by immunizing animals with synthetic peptide derived from human M-Cadherin

Format: Lyophilized

Wiederherstellung: Reconstitute with 100ul sterille distilled water. After reconstitution, stock concentration=1ug/1ul, preservatives included (BSA=10ug/ul, Sodium azide=0.1%)

Isotyp: IgG  (Passende Sekundärantikörper)

Beschreibung: Synonym: Cadherin 14, Cadherin 15, Cadherin 3, Cadherin14, Cadherin15, Cadherin3, CCAD, CDH 14,CDH 15, CDH 3, CDH14, CDH15,CDH3, CDHuman, MCAD, Muscle cadherin, Myotubule cadherin.

Molekulargewicht: 89kDa

Kommentare:

Cadherins are a family of transmembrane glycoproteins that play a key role in Calcium dependent cell-cell adhesion. Several members of the cadherin family have been identified so far

including E- (epithelial)

P- (placental)

N- (neuronal) and M- (muscle) cadherin. Cadherins consist of an extracellular domain containing 5 cadherin domains

a transmembrane region

and a conserved cytoplasmic domain. Transcripts from this particular cadherin are expressed in myoblasts and upregulated in myotubule-forming cells. M-Cadherin is thought to be essential for the control of morphogenetic processes

specifically myogenesis

and may provide a trigger for terminal muscle cell differentiation.

Anwendungen

Applikationshinweise: WB (1:100-500), ELISA (1:500-1000), IP (1:20-100), IHC-P (1:100-500), IHC-F (1:100-500), Flow-Cyt (1:20-100), IF (1:50-200)

Konzentration: 1mg/1ml

Reinigung: affinity purified by Protein A

Buffer: Preservative: 15mM Sodium Azide, Constituents: 1% BSA, 0.01M PBS, pH 7.4

Lagerung: Ship at room temperature. Store at -20°C

Beschränkungen: Nur für Forschungszwecke einsetzbar