DIO2 Antikörper (AA 101-200) (Cy5)
Kurzübersicht für DIO2 Antikörper (AA 101-200) (Cy5) (ABIN702464)
Target
Alle DIO2 Antikörper anzeigenReaktivität
Wirt
Klonalität
Konjugat
Applikation
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Bindungsspezifität
- AA 101-200
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Kreuzreaktivität
- Maus, Ratte
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Homologie
- Human,Dog,Cow,Sheep,Pig,Horse,Rabbit
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Aufreinigung
- Purified by Protein A.
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Immunogen
- KLH conjugated synthetic peptide derived from human DIO2
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Isotyp
- IgG
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Applikationshinweise
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 -
Beschränkungen
- Nur für Forschungszwecke einsetzbar
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Format
- Liquid
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Konzentration
- 1 μg/μL
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Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
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Konservierungsmittel
- ProClin
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Vorsichtsmaßnahmen
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
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Lagerung
- -20 °C
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Informationen zur Lagerung
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
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Haltbarkeit
- 12 months
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- DIO2 (Deiodinase, Iodothyronine, Type II (DIO2))
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Andere Bezeichnung
- DIO2
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Hintergrund
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Synonyms: 5DII, D2, Deiodinase, iodothyronine, type II, DIOII, ITDI2, SelY, Thyroxine deiodinase, type II, TXDI2, Type 2 DI, Type II 5' deiodinase, Type II iodothyronine deiodinase.
Background: DIO2 belongs to the iodothyronine deiodinase family and is responsible for the deiodination of T4 (3,5,3',5'-tetraiodothyronine) into T3 (3,5,3'-triiodothyronine). It is essential for providing the brain with appropriate levels of T3 during the critical period of development. DIO2 is expressed in heart, skeletal muscle, placenta, fetal brain and several regions of the adult brain. There are two named isoforms.
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Gen-ID
- 1734
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Pathways
- Hormone Transport, Hormone Activity
Target
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