DEFA4 Antikörper (AA 41-97) (Biotin)

Produktnummer ABIN680880

Der Biotin-konjugierte Kaninchen Polyklonal anti-DEFA4 Antikörper (ABIN680880) detektiert spezifisch DEFA4 in ELISA, IHC (p) und IHC (fro). Dieser Antikörper reagiert spezifisch mit Proben aus Human.

Kurzübersicht für DEFA4 Antikörper (AA 41-97) (Biotin) (ABIN680880)

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Reaktivität: Human

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser DEFA4 Antikörper ist konjugiert mit Biotin

Applikation: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-DEFA4 Antikörper (Biotin)

Bindungsspezifität: AA 41-97

Homologie: Human

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Defensin alpha 4

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: IHC-P 1:200-400
IHC-F 1:100-500

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: -20 °C

Informationen zur Lagerung: Store at -20°C for 12 months.

Haltbarkeit: 12 months

Details zu DEFA4

Target: DEFA4 (Defensin, alpha 4, Corticostatin (DEFA4))

Andere Bezeichnung: Defensin alpha 4

Hintergrund:

Synonyms: Neutrophil defensin 4, Defensin, alpha 4, HNP-4, HP-4, defensin, alpha 4, corticostatin, neutrophil defensin 4 precursor, neutrophil defensin 4 preproprotein.

Background: Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes are clustered on chromosome 8. This gene differs from other genes of this family by an extra 83-base segment that is apparently the result of a recent duplication within the coding region. The protein encoded by this gene, defensin, alpha 4, is found in the neutrophils, it exhibits corticostatic activity and inhibits corticotropin stimulated corticosterone production. [provided by RefSeq].

Gen-ID: 1669