Hemagglutinin Antikörper (AA 200-300)

Produktnummer ABIN679238

Es sind 2+ Publikationen für dieses Produkt verfügbar. Der Kaninchen Polyklonal anti-Hemagglutinin Antikörper wird verwendet zum Nachweis von Hemagglutinin in Proben von Influenza A Virus H5N1 und Virus. Er wurde validiert für ELISA, WB, IF (p), IF (cc), IHC (p) und IHC (fro).

Kurzübersicht für Hemagglutinin Antikörper (AA 200-300) (ABIN679238)

Target: Hemagglutinin (HA)

Reaktivität: Influenza A Virus H5N1, Virus

Wirt: Kaninchen

Klonalität: Polyklonal

Konjugat: Dieser Hemagglutinin Antikörper ist unkonjugiert

Applikation: ELISA, Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Produktdetails anti-Hemagglutinin Antikörper

Bindungsspezifität: AA 200-300

Virus Strain: A/chicken/West Bengal/100879/2008

Kreuzreaktivität: Virus

Kreuzreaktivität (Details): Influenza A virus H5N1

Aufreinigung: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from Hemagglutinin/Influenza A virus (H5N1)

Isotyp: IgG

Anwendungsinformationen

Applikationshinweise: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Beschränkungen: Nur für Forschungszwecke einsetzbar

Handhabung

Format: Liquid

Konzentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Konservierungsmittel: ProClin

Vorsichtsmaßnahmen: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Lagerung: 4 °C,-20 °C

Informationen zur Lagerung: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Haltbarkeit: 12 months

Referenzen für anti-Hemagglutinin Antikörper (ABIN679238)

Lv, Li, Liu, Li, Liu, Shen, Wang, Xue, Cao: "Production and immunogenicity of chimeric virus-like particles containing the spike glycoprotein of infectious bronchitis virus." in: Journal of veterinary science, Vol. 15, Issue 2, pp. 209-16, (2015) (PubMed).

Lee, Na, Yang, Choi, Seo, Hong, Yun, Kim, Sohn, Kim, Sung, Kim, Jang, Hwang: "Oral immunization of haemaggulutinin H5 expressed in plant endoplasmic reticulum with adjuvant saponin protects mice against highly pathogenic avian influenza A virus infection." in: Plant biotechnology journal, (2014) (PubMed).

Details zu Hemagglutinin

Target: Hemagglutinin (HA)

Andere Bezeichnung: H5N1 Hemagglutinin

Substanzklasse: Influenza Protein

Hintergrund:

Synonyms: [Influenza A virus A/chicken/West Bengal/100879/2008H5N1], Influenza A virus Hemagglutinin[H5N1.

Background: Influenza A virus is a major public health threat. Novel influenza virus strains caused by genetic drift and viral recombination emerge periodically to which humans have little or no immunity, resulting in devastating pandemics. Influenza A can exist in a variety of animals, however it is in birds that all subtypes can be found. These subtypes are classified based on the combination of the virus coat glycoproteins hemagglutinin (HA) and neuraminidase (NA) subtypes. During 1997, an H5N1 avian influenza virus was determined to be the cause of death in 6 of 18 infected patients in Hong Kong. There was some evidence of human to human spread of this virus, but it is thought that the transmission efficiency was fairly low. HA interacts with cell surface proteins containing oligosaccharides with terminal sialyl residues. Virus isolated from a human infected with the H5N1 strain in 1997 could bind to oligosaccharides from human as well as avian sources, indicating its species jumping ability. Influenza A Virus Hemagglutinin recognize the influenza hemagglutinin epitope, which has been used extensively as a general epitope tag in expression vectors. The extreme specificity of this antibody allows for unambiguous identification and quantitative analysis of the tagged protein.